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Multiple lymphoid polyposis and familial polyposis of the colon: A Genetic relationship

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Diseases of the Colon & Rectum

Summary

A case of multiple lymphoid polyposis of the colon and terminal ileum occurring in a family of familial polyposis is presented. Only one other such case has been reported. Other cases where an association between the conditions was mentioned are reviewed.

There is a genetic factor in the etiology of the condition, and a definite link with familial, polyposis of the colon is found to exist. Differentiation of the conditions on clinical grounds could be very difficult.

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References

  1. Ackerman LV: Malignant protential of polyposis lesions of the large intestine. S Afr Cancer Bull 9: 5, 1965

    Google Scholar 

  2. Ackerman LV, Butcher HR Jr: Surgical Pathology. Ed 3, St. Louis, C. V. Mosby Company, 1964, 1244 pp

    Google Scholar 

  3. Briquet: Cruelhier's Atlas. Paris: J. B. Balliere, 1835–1842, vol 2, p 1

    Google Scholar 

  4. Cohnheim J: Ein fall von Pseudoleukemia. Arch Path (Path Anat) Klin Med 33: 451, 1865

    Google Scholar 

  5. Cornes JS: Multiple lymphomatous polyposis of the gastrointestinal tract. Cancer 14: 249, 1961

    Article  PubMed  CAS  Google Scholar 

  6. Cosens CG: Gastros-intestinal pseudoleukemia: A case report. Ann Surg 148: 129, 1958.

    Article  PubMed  CAS  Google Scholar 

  7. Dorazio RA, Whelan TJ Jr: Lymphoid hyperplasia of the terminal ileum associated with familial polyposis coli. Ann Surg 171: 300, 1971

    Article  Google Scholar 

  8. Dukes C, Bussey HJ: The number of lymphoid follicles of the human large intestine. J Pathol 29: 111, 1926

    Article  Google Scholar 

  9. Fiwing J: Neoplastic Diseases; a Treatise on Tumors, Ed 4 Philadelphia. W. B. Saunders Company, 1940, 1160 pp

    Google Scholar 

  10. Fieber SS, Schaefer HJ: Lymphoid hyperplasia of the terminal ileum—a clinical entity? Gastroenterology 50: 83, 1966.

    PubMed  CAS  Google Scholar 

  11. Granet E: Simple lymphoma of the sphincteric rectum in identical twins. JAMA 141: 990, 1949

    CAS  Google Scholar 

  12. Gruenberg J: Mackman S: Multiple lymphoid polyps in familial polyposis. Ann Surg 175: 552, 1972

    Article  PubMed  CAS  Google Scholar 

  13. Helwig EB, Hansen J: Lymphoid polyps (benign lymphoma) and malignant lymphoma of the rectum and anus. Surg Gynecol Obstet 92: 233, 1951

    PubMed  CAS  Google Scholar 

  14. Hermans PE, Huzenga KA, Hoffman HN, et al: Dysgammaglobulinemia associated with nodular lymphoid hyperplasia of the small intestine. Am J Med 40: 78, 1966

    Article  PubMed  CAS  Google Scholar 

  15. Hodgson JR, Hoffman HN, Huizenga KA: Roentgenologic features of lymphoid hyperplasia of the small intestine associated with dysgammaglobulinemia. Radiology 88: 883 1967

    PubMed  CAS  Google Scholar 

  16. Keeling WM, Beatty GL: Lymphoid polyps of the rectum: Report of three cases in siblings. Arch Surg 73,: 753, 1956

    Google Scholar 

  17. LoGerfo FW, Mueller RF: Lymphoid polyposis of the terminal ileum and colon: A source of clinical error. Am Surg 41: 179, 1975

    PubMed  CAS  Google Scholar 

  18. Louw JH: Polypoid lesions of the large bowel in children with particular reference to benign lymphoid polyposis. J Pediatr Surg 3: 195, 1968

    Article  PubMed  CAS  Google Scholar 

  19. Marino FC, Rof CJ: Exploration del ileon terminal. Rev. Clin Esp 3: 97, 1941

    Google Scholar 

  20. Neitzschman HR, Genet E, Nice CM Jr: Two cases of familial polyposis simulating lymphoid hyperplasia. Am J Roentgenol Radium Ther Nucl Med 119: 365, 1973

    PubMed  CAS  Google Scholar 

  21. Peterson GM: Intestinal changes in Giardial lamblia infestation. Am J Roentgenol Radium The Nucl Med 77: 670, 1957.

    CAS  Google Scholar 

  22. Shaw EB, Hennigar GR: Intestinal lymphoid polyposis. Am J Clin Path 61: 417, 1974

    PubMed  Google Scholar 

  23. Shull LN Jr, Fitts CT: Lymphoid polyposis associated with familial polyposis and Gardner's syndrome. Ann Surg 180: 319, 1974

    Article  PubMed  Google Scholar 

  24. Swartley RN, Stayman JW Jr: Lymphoid hyperplasia of the intestinal tract requiring surgical intervention. Ann Surg 155: 238, 1962

    PubMed  CAS  Google Scholar 

  25. Symmers D: Lymphoid diseases: Hodgkin's granuloma, giant pollicular lymphadenopathy, lymphoid leukemia, lymphosarcoma and gastrointestinal pseudoleukemia. Arch Pathol 45: 73, 1948

    CAS  Google Scholar 

  26. Thomford NR, Greenberg NJ: Lymphoid polyps of the ileum associated with Gardner's syndrome. Arch Surg 96: 289, 1968

    PubMed  CAS  Google Scholar 

  27. Thompson DH: Multiople lymphomatous polyposis of the gastrointestinal tract. Br J Surg 50: 813, 1963

    Article  PubMed  CAS  Google Scholar 

  28. Vanhoutte JJ: Polypoid lymphoid hyperplasia of the terminal ileum in patients with fmailial polyposis coli and Gardner's syndrome. Am J Roentgenol Radium Ther Nucl Med 110: 340, 1970

    PubMed  CAS  Google Scholar 

  29. Veale AM: Intestinal polyposis, Eugenics Laboratories Memoirs XL, Galton Lab, University College, London, Cambridge University Press, 1965

    Google Scholar 

  30. Vealek AM, McColl I, Bussey HJ, et al: Juvenile poly posis coli. J Med Genet 3: 5, 1966

    Article  Google Scholar 

  31. Wells J: The mucosal pattern of the terminal ileum in children: Preliminary report. Radiology 51: 305, 1948.

    PubMed  CAS  Google Scholar 

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Venkitachalam, P.S., Hirsch, E., Elguezabal, A. et al. Multiple lymphoid polyposis and familial polyposis of the colon: A Genetic relationship. Dis Colon Rectum 21, 336–341 (1978). https://doi.org/10.1007/BF02586662

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  • DOI: https://doi.org/10.1007/BF02586662

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