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Transcatheter embolization of the kidney with butyl-2-cyanoacrylate: Experimental and clinical results

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Abstract

The technique and efficacy of therapeutic catheter embolization of the kidney with butyl-2-cyanoacrylate (Histoacryl) were studied in 80 rabbits (including control groups) and in 10 dogs. A mixture of butyl-2-cyanoacrylate, 50% glucose, and tantalum powder was used for the embolization. Complete and permanent vascular occlusion was found in nearly all cases. The main complication observed was a reflux of embolizing material into the lumbar arteries, which occurred in seven rabbits. Clinically, therapeutic embolization was performed in six patients with hypernephroma. The indication for embolization in these patients, as well as in two others with iatrogenic lesions, was pronounced hematuria. Cessation of bleeding was achieved in all cases. For embolization the coaxial catheter technique is recommended; in special cases with extensive arteriovenous shunts, adjunctive balloon occlusion would be advisable.

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References

  1. Bischoff, W., Goerttler, U.: Aktuelle Aspekte der renalen Gefäßembolisation. Dtsch. med. Wschr. 102:901–906, 1977

    Article  PubMed  CAS  Google Scholar 

  2. Bookstein, J.J., Chlosta, E.M., Foley, D., Walter, J.F.: Transcatheter hemostasis of gastrointestinal bleeding using modified autogenous clot. Radiology 113:277–285, 1974

    PubMed  CAS  Google Scholar 

  3. Bracken, R.B., Johnson, D.E., Goldstein, H.M., Wallace, S., Ayala, A.G.: Percutaneous transfemoral renal artery occlusion in patients with renal carcinoma. Urology 6:6–10, 1975

    Article  PubMed  CAS  Google Scholar 

  4. Buzelin, J.-M., Bourdon, J., Mitard, D., Buzelin, F., Auvigne, J.: L'embolisation de l'artère rénale. Etude expérimentale. Application au traitement des cancers du rein. J. Urol. Nephrol. 80:541–553, 1974

    CAS  Google Scholar 

  5. Djindjian, R., Cophignon, J., Théron, J., Merland, J.J., Houdart, R.: Embolization by superselective arteriography from the femoral route in neuroradiology: Review of 60 cases. I. Technique, indications, complications. Neuroradiology 6:20–26, 1973

    Article  PubMed  CAS  Google Scholar 

  6. Dotter, C.T., Goldman, M.L., Rösch, J.: Instant selective arterial occlusion with isobutyl 2-cyanoacrylate. Radiology 114:227–230, 1975

    PubMed  CAS  Google Scholar 

  7. Eisenberg, H., Steer, M.L.: The nonoperative treatment of massive pyloroduodenal hemorrhage by retracted autologous clot embolization. Surgery 79:414–420, 1976

    PubMed  CAS  Google Scholar 

  8. Gang, D.L., Dole, K.B., Adelman, L.S.: Spinal cord infarction following therapeutic renal artery embolization. JAMA 237:2841–2842, 1977

    Article  PubMed  CAS  Google Scholar 

  9. Georgi, M., Marberger, M., Kaufmann, A.: Embolisation eines inoperablen Nierentumors durch intraarterielle Applikation von Thrombin bei Ballonverschluß der Nierenarterie. Dtsch. med. Wschr. 100:2428–2429, 1975

    Article  PubMed  CAS  Google Scholar 

  10. Giuliani, L., Carmignani, G., Belgrano, E., Puppo, P.: Embolisation des cancers du rein avec l'isobutyl-2-cyanoacrylate. Etude expérimentale. Premières applications cliniques. J. Radiol. Electrol. 58:419–425, 1977

    PubMed  CAS  Google Scholar 

  11. Goldin, A.R.: Control of duodenal hemorrhage with cyanoacrylate. Brit. J. Radiol. 49:583–588, 1976

    Article  PubMed  CAS  Google Scholar 

  12. Goldman, M.L., Land, W.C., Jr., Bradley, E.L. III, Anderson, J.: Transcatheter therapeutic embolization in the management of massive upper gastrointestinal bleeding. Radiology 120:513–521, 1976

    PubMed  CAS  Google Scholar 

  13. Goldstein, H.M., Wallace, S., Anderson, J.H., Bree, R.L., Gianturco, C.: Transcatheter occlusion of abdominal tumors. Radiology 120:539–545, 1976

    PubMed  CAS  Google Scholar 

  14. Grace, D.M., Pitt, D.F., Gold, R.E.: Vascular embolization and occlusion by angiographic techniques as an aid or alternative to operation. Surg. Gyn. Obstet. 143:469–482, 1976

    CAS  Google Scholar 

  15. Günther, R., Jonas, U., Jacobi, G.H.: Nierenläsion bei translumbaler Aortographie und Therapie durch selektive Katheterembolisierung. Fortschr. Röntgenstr. 126:426–429, 1977

    Google Scholar 

  16. Kaufmann, G., Bischoff, W., Wimmer, B., Roth, F.J.: Die Wertigkeit experimenteller Arterienverschlüsse unter besonderer Berücksichtigung ihrer Komplikationen. Fortschr Röntgenstr. 125:445–452, 1976

    Google Scholar 

  17. Kerber, C.: Experimental arteriovenous fistula: Creation and percutaneous obstruction with cyanoacrylate. Invest. Radiology 10:10–17, 1975

    Article  CAS  Google Scholar 

  18. Kotter, A., Müller, I.: Darstellung der Gewebekleber im histologischen Bild. In: Kunststoffe in der Chirurgie, Symposium, Innsbruck February 13–16, 1969. Urban & Schwarzenberg. Wien, pp. 169–171

  19. Lalli, A.F., Bookstein, J.J., Lapides, J.: Experimental renal infarctions in dogs. Invest. Urol. 8:516–520, 1971

    PubMed  CAS  Google Scholar 

  20. Luessenhop, A.J., Kachmann, R., Shelvin, W., Ferrero, A.A.: Clinical evaluation of artificial embolization in the management of large cerebral arteriovenous malformations. J. Neurosurg 23:400–417, 1965

    Google Scholar 

  21. Marberger, M., Georgi, M., Günther, R., Schäfer, R., Hohenfellner, R.: Die intraluminale Ballonokklusion der Nierenarterie. Klinische Anwendungsmöglichkeit und Erfahrungen. Urologe 16:146–153, 1977

    PubMed  CAS  Google Scholar 

  22. Matsumoto, T.: Tissue adhesives in surgery. London, Lewis & Co., Ltd., 1972

    Google Scholar 

  23. Pontes, J.E., Parekh, N., McGuckin, J.T., Banks, M.D., Pierce, J.M.: Percutaneous transfemoral embolization of arterio-infundibular-venous fistula. J. Urol. 116:98–100, 1976

    PubMed  CAS  Google Scholar 

  24. Prochaska, J.M., Flye, M.W., Johnsrude, I.S.: Left gastric artery embolization for control of gastric bleeding: A complication. Radiology 107:521–522, 1973

    PubMed  CAS  Google Scholar 

  25. Rösch, J., Goldman, M.L., Dotter, C.T.: Experimental obstruction of the gastric coronary vein. Invest. Radiol. 10:206–211, 1975

    Article  PubMed  Google Scholar 

  26. Steckenmesser, R., Bayindir, S., Rothauge, C.F., Nöske, K., Weidner, W.: Embolisation maligner Nierentumoren. Bericht über 22 Fälle Fortschr. Röntgenstr. 125:251–257, 1976

    CAS  Google Scholar 

  27. Tadavarthy, S.M., Knight, L., Ovitt, T.W., Snyder, C., Amplatz, K.: Therapeutic transcatheter arterial embolization. Radiology 111:13–16, 1974

    Google Scholar 

  28. Tegtmeyer, C.J., Smith, T.H., Shaw, A., Barwick, K.W., Kattwinkel, J.: Renal infarction A complication of gelfoam embolization of a hemangioendothelioma of the liver. Am. J. Roentgenol. 128:305–307, 1977

    CAS  Google Scholar 

  29. Thelen, M., Brühl, P., Gerlach, F., Biersack, H.J.: Katheterembolisation von metastasierten Nierenkarzinomen mit Butyl-2-cyanoacrylat. Fortschr. Röntgenstr. 124:232–235, 1976

    Article  CAS  Google Scholar 

  30. Woodside, J., Schwarz, H., Bergreen, P.: Peripheral embolization complicating bilateral renal infarction with gelfoam. Am. J. Roentgenol. 126:1033–1034, 1976

    CAS  Google Scholar 

  31. Zanetti, P.H., Sherman, F.E.: Experimental evaluation of tissue adhesive as an agent for the treatment of aneurysms and arteriovenous anomalies. J. Neurosurg. 36:72–79, 1972

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Departments of Radiology, Pathology and Urology, University of Mainz Medical School, Mainz, FRG

    R. Günther, U. Schubert, J. Bohl, M. Georgi & M. Marberger

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  1. R. Günther
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  2. U. Schubert
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  3. J. Bohl
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  4. M. Georgi
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  5. M. Marberger
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Günther, R., Schubert, U., Bohl, J. et al. Transcatheter embolization of the kidney with butyl-2-cyanoacrylate: Experimental and clinical results. Cardiovasc Radiol 1, 101–108 (1978). https://doi.org/10.1007/BF02552003

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