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Some new aspects of isoprenoid biosynthesis in plants—A review

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Lipids

Abstract

Plants are capable of synthesizing a myriad of isoprenoids and prenyl lipids. Much attention has been focused on 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR), the enzyme that synthesizes mevalonate and is generally considered responsible for the regulation of substrate flux to isoprenoids. In contrast to vertebrates, where there seems to exist only one HMGR gene, in plants a small family of isogenes appears differentially expressed in regard to location and time. Much less is known in plants about the preceding steps,viz. the conversion of acetyl-CoA to HMG-CoA. An enzyme system has been isolated from radish that can catalyze this transformation, and which shows some unusual propertiesin vitro. The intracellular localization of the early steps of isoprenoid biosynthesis in plant cells is still a matter of debate. The various observations and hypotheses derived from incorporation and inhibition studies are somewhat contradictory, and an attempt is being made to rationalize various findings that do not at first seem compatible. There are good arguments in favor of an exclusively cytoplasmic formation of isopentenyl pyrophosphate (IPP) via mevalonic acid, but other studies and observations suggest an independent formation in plastids. Other possibilities are being considered, such as the existence of independent (compartmentalized) biosynthetic pathways of IPP formationvia the socalled Rohmer pathway. Substrate channeling through the formation of end product-specific multienzyme complexes (metabolons) with no release of substrate intermediates will also be discussed.

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Abbreviations

AACT:

acetoacetyl-CoA thiolase

ALS:

acetolactate synthase

CAL:

chalcomoracin

DMAPP:

dimethylallyl pyrophosphate

HMG-CoA:

3-hydroxy-3-methylglutaryl-CoA

HMGL:

HMG-CoA lyase

IPP:

isopentenyl pyrophosphate

MVA:

mevalonic acid

MVAP:

mevalonate phosphate

MVAPP:

mevalonate pyrophosphate

PDC:

pyruvate decarboxylase

PP:

pyrophosphate

PQQ:

pyrroloquinoline quinone

SRP:

signal recognition particle

TPP:

thiamine diphosphate

References

  1. Conolly, J.D., and Hill, R.A. (1992)Dictionary of Terpenoids, Chapman and Hall, New York.

    Google Scholar 

  2. Wahlberg, I., and Enzell, C.R. (1987)Nat. Prod. Rep. 4, 237–276.

    Article  PubMed  CAS  Google Scholar 

  3. Wolf, D.E., Hoffman, C.H., Aldrich, P.E., Skeggs, H.R., Wright, L.D., and Folkers, K. (1956)J. Am. Chem. Soc. 78, 4499.

    Article  CAS  Google Scholar 

  4. Tavormina, P.A., and Gibbs, M.H. (1956)J. Am. Chem. Soc. 78, 6210.

    Article  CAS  Google Scholar 

  5. Tavormina, P.A., Gibbs, M.H., and Huff, J.W. (1956)J. Am. Chem. Soc. 78, 4498–4499.

    Article  CAS  Google Scholar 

  6. Goodwin, T.W. (ed.) (1970)Natural Substances Formed Biologically from Mevalonic Acid, Biochem. Soc. Symp. No. 29, Liverpool 1969, Academic Press, New York.

    Google Scholar 

  7. Banthorpe, D.V., Charlwood, B.V., and Francis, M.J.O. (1972)Chem. Rev. 72, 115–149.

    Article  PubMed  CAS  Google Scholar 

  8. Nes, W.R., and McKean, M.L. (1977)Biochemistry of Steroids and Other Isopentenoids, University Park Press, Baltimore.

    Google Scholar 

  9. Porter, J., and Spurgeon, S.L. (eds.) (1981)Biosynthesis of Isoprenoid Compounds, Vol. 1, John Wiley and Sons, New York.

    Google Scholar 

  10. Goad, L.J. (1983)Biochem. Soc. Transact. 11, 548–552.

    CAS  Google Scholar 

  11. Kleinig, H. (1989)Annu. Rev. Plant Physiol. Plant Mol. Biol. 40, 39–59.

    Article  CAS  Google Scholar 

  12. Nes, W.D., and Bach, T.J. (1985)Proc. Roy. Soc. Lond. B 225, 425–444.

    Article  CAS  Google Scholar 

  13. Bach, T.J. (1986)Lipids 21, 82–88.

    Article  PubMed  CAS  Google Scholar 

  14. Gray, J.C. (1987)Adv. Bot. Res. 14, 25–91.

    Article  CAS  Google Scholar 

  15. West, C. (1990) inPlant Physiology, Biochemistry and Molecular Biology (Dennis, D.T., and Turpin, D.H., eds.) pp. 353–369, Longman Scientific & Technical, Essex.

    Google Scholar 

  16. Bach, T.J., Motel, A., and Weber, T. (1990)Rec. Adv. Phytochemistry 24, 1–82.

    CAS  Google Scholar 

  17. Alberts, A.W., Chen, J., Kuron, G., Hunt, V., Huff, J., Hoffman, C., Rothrock, J., Lopez, M., Joshua, H., Harris, E., Patchett, A., Monaghan, R., Currie, S., Stapley, E., Albers-Schönberg, G., Hensens, O. Hirshfield, J., Hoogsteen, K., Liesch, J., and Springer, J. (1980)Proc. Natl. Acad. Sci. U.S.A. 77, 3957–3961.

    Article  PubMed  CAS  Google Scholar 

  18. Bach, T.J., and Lichtenthaler, H.K. (1982)Z. Naturforsch. C. 37, 46–50.

    PubMed  CAS  Google Scholar 

  19. Bach, T.J., and Lichtenthaler, H.K. (1983)Z. Naturforsch. C., 38, 212–219.

    PubMed  CAS  Google Scholar 

  20. Nakamura, C.E., and Abeles, R.H. (1985)Biochemistry 24, 1364–1376.

    Article  PubMed  CAS  Google Scholar 

  21. Louis-Flamberg, P., Peishoff, C.E., Bryan, D.L., Leber, J., Elliot, J.D., Metcalf, B.W., and Mayer, R.J. (1990)Biochemistry 29, 4115–4120.

    Article  PubMed  CAS  Google Scholar 

  22. Bach, T.J., and Lichtenthaler, H.K. (1983)Physiol. Plant. 59, 50–60.

    Article  CAS  Google Scholar 

  23. Bach, T.J., and Lichtenthaler, H.K. (1987) inEcology and Metabolism of Plant Lipids (Fuller, G., and Nes, W.D., eds.),Am. Chem. Soc. Symposium Series 325, pp. 109–139, American Chemical Society, Washington, DC.

    Google Scholar 

  24. Hata, S., Takagishi, H., Egawa, Y., and Ota, Y. (1986)Plant Growth Regul. 4, 335–346.

    CAS  Google Scholar 

  25. Hata, S., Takagishi, H., and Kouchi, H. (1987)Plant Cell Physiol. 28, 709–714.

    CAS  Google Scholar 

  26. Maillot-Vernier, P., Gondet, L., Schaller, H., Benveniste, P., and Belliard, G. (1991)Mol. Gen. Genet. 231, 33–40.

    Article  PubMed  CAS  Google Scholar 

  27. Gondet, L., Weber, T., Maillot-Vernier, P., Benveniste, P., and Bach, T.J. (1992)Biochem. Biophys. Res. Commun. 186, 888–893.

    Article  PubMed  CAS  Google Scholar 

  28. Gondet, L. (1993) Caractérisation biochimique et cytochimique d'un mutant de tabac (Nicotiana tabacum L.) surproducteur de stérols. Thèse doctorale, Université Louis Pasteur, Strasbourg, France.

    Google Scholar 

  29. Gondet, L., Bronner, R., and Benveniste, P. (1994)Plant. Physiol. 105, 509–518.

    PubMed  CAS  Google Scholar 

  30. Chappell, J., Proulx, J., Wolf, F., Cuellar, R.E., and Saunders, C. (1991)Plant Physiol. 96 (Suppl.), 127.

    Google Scholar 

  31. Hata, S., Shirata, K., and Takagishi, H., and Kouchi, H. (1987)Plant Cell Physiol. 28, 715–722.

    CAS  Google Scholar 

  32. Kyte, J., and Doolittle, R.F. (1982)J. Mol. Biol. 157, 105–132.

    Article  PubMed  CAS  Google Scholar 

  33. Narita, J.O., and Gruissem, W. (1989)Plant Cell 1, 181–190.

    Article  PubMed  CAS  Google Scholar 

  34. Caelles, C., Ferrer, A., Balcells, L., Hegardt, F.G., and Boronat, A. (1989)Plant Mol. Biol. 13, 627–638.

    Article  PubMed  CAS  Google Scholar 

  35. Learned, R.M., and Fink, G.R. (1989)Proc. Natl. Acad. Sci. USA 86, 2779–2783.

    Article  PubMed  CAS  Google Scholar 

  36. Monfar, M., Caelles, C., Balcells, L., Ferrer, A., Hegardt, F.G., and Boronat, A. (1990)Rec. Adv. Phytochemistry 24, 83–98.

    CAS  Google Scholar 

  37. Wettstein, A., Caelles, C., Boronat, A., Jenke, H.-S., and Bach, T.J. (1989)Biol. Chem. Hoppe-Seyler 370, 806–807.

    Google Scholar 

  38. Ferrer, A., Aparicio, C., Nogués, N., Wettstein, A., Bach, T.J. and Boronat, A. (1990)FEBS Lett. 266, 67–71.

    Article  PubMed  CAS  Google Scholar 

  39. Dittrich, B., Boronat, A., Ferrer, A., and Bach, T.J. (1991)Biol. Chem. Hoppe-Seyler 372, 528.

    Google Scholar 

  40. Chye, M.-L., Kush, A., Tan, C.-T., and Chua, N.-H. (1991)Plant Mol. Biol. 16, 567–577.

    Article  PubMed  CAS  Google Scholar 

  41. Chye, M.-L., Tan, C.-T., and Chua, N.-H. (1992)Plant Mol. Biol. 19, 473–484.

    Article  PubMed  CAS  Google Scholar 

  42. Bach, T.J., Boronat, A., Caelles, C., Ferrer, A., Weber, T., and Wettstein, A. (1991)Lipids 26, 637–648.

    Article  PubMed  CAS  Google Scholar 

  43. Sterner, B.A., Edwards, L.A., Edington, B.V., and Dixon, R.A. (1991)Physiol. Mol. Plant Pathol. 39, 135–145.

    Article  Google Scholar 

  44. Park, H., Denbow, C.J., and Cramer, C.L. (1992)Plant Mol. Biol. 20, 327–331 (1992).

    Article  PubMed  CAS  Google Scholar 

  45. Genschik, P., Criqui, M.-C., Parmentier, Y., Marbach, J.A., Durr, A., Fleck, J., and Jamet, E. (1992)Plant Mol. Biol. 20, 337–341.

    Article  PubMed  CAS  Google Scholar 

  46. Maldonado-Mendoza, I.E., Burnett, R.J., and Nessler, C.L. (1992)Plant Physiol. 100, 1613–1614.

    PubMed  CAS  Google Scholar 

  47. Oosterhaven, K., Hartmans, K.J., and Huitzing, H.J. (1993)J. Plant Physiol. 141, 463–469.

    CAS  Google Scholar 

  48. Burnett, R.J., Maldonado-Mendoza, I.E., McKnight, T.D., and Nessler, C.L. (1993)Plant Physiol. 103, 41–48.

    Article  PubMed  CAS  Google Scholar 

  49. Bach, T.J., Wettstein, A., Boronat, A., Ferrer, A., Enjuto, M., Gruissem, W., and Narita, J.O. (1991) inPhysiology and Biochemistry of Sterols (Patterson, G.W., and Nes, W.D., eds.), pp. 29–49, American Oil Chemists' Society, Champaign.

    Google Scholar 

  50. Enjuto, M., Balcells, L., Campos, N., Caelles, C., Arró, M., and Boronat, A. (1994)Proc. Natl. Acad. Sci. USA 91, 927–931.

    Article  PubMed  CAS  Google Scholar 

  51. Wong, R.J., McCormack, K., and Russell, D.W. (1982)Arch. Biochem. Biophys. 216, 631–638.

    Article  PubMed  CAS  Google Scholar 

  52. Wititsuwannakul, R. (1986)Experientia 42, 44–46.

    Article  CAS  Google Scholar 

  53. Bach, T.J. (1987)Plant Physiol. Biochem. 25, 163–178.

    CAS  Google Scholar 

  54. Stermer, B.A., and Bostock, R.M. (1987)Plant Physiol. 84, 404–408.

    PubMed  CAS  Google Scholar 

  55. Chappell, J., and Nable, R. (1989)Plant Physiol. 85, 469–473.

    Google Scholar 

  56. Chappell, J., von Lanken, C., Vögeli, U., and Bhatt, P. (1989)Plant Cell Reports 8, 48–52.

    Article  CAS  Google Scholar 

  57. Boll, M., and Kardinal, A. (1990)Z. Naturforsch. 45, 973–979.

    CAS  Google Scholar 

  58. Wititsuwannakul, R., Wititsuwannakul, D., and Dumchong, S. (1990)Phytochemistry 29, 1755–1758.

    Article  CAS  Google Scholar 

  59. Yang, Z., Park, H., Lacy, G.H., and Cramer, C.L. (1991)Plant Cell 3, 397–405.

    Article  PubMed  CAS  Google Scholar 

  60. Choi, D., Ward, B.L., and Bostock, R.M. (1992)Plant Cell 4, 1333–1344.

    Article  PubMed  CAS  Google Scholar 

  61. Ji, W., and Hatzios, K.K. (1992)Pesticide Biochem. Physiol. 42, 54–63.

    Article  CAS  Google Scholar 

  62. Ji, W., Hatzios, K.K., and Cramer, C.L. (1992)Physiol. Plant. 84, 185–192.

    Article  CAS  Google Scholar 

  63. Wilson, T.M., and Russell, D.W. (1992)Biochem. Biophys. Res. Commun. 184, 530–537.

    Article  PubMed  CAS  Google Scholar 

  64. Mackintosh, R.W., Davies, S.P., Clarke, P.R., Weekes, J., Gillepsie, J.G., Gibb, B.J., and Hardie, D.G. (1992)Eur. J. Biochem. 209, 923–931.

    Article  PubMed  CAS  Google Scholar 

  65. Moore, K.B., and Oishi, K.K. (1993)Plant Physiol. 101, 485–491.

    PubMed  CAS  Google Scholar 

  66. Choi, D., and Bostock, R.M. (1994)Plant Physiol. 104, 1237–1244.

    PubMed  CAS  Google Scholar 

  67. Gershenzon, J., and Croteau, R. (1990)Rec. Adv. Phytochem. 24, 99–160.

    CAS  Google Scholar 

  68. Stermer, B.A., Bianchini, G.M., and Korth, K.L. (1994)J. Lipid Res. 35, 1133–1140.

    PubMed  CAS  Google Scholar 

  69. Darney, B.G., Wang, Y.L., and Rodwell, V.W. (1992)J. Biol. Chem. 267, 15064–15070.

    Google Scholar 

  70. Oldender, E.H., and Simoni, R.D. (1992)J. Biol. Chem. 267, 4223–4235.

    Google Scholar 

  71. Roitelman, J., Olender, E.H., Barnum, S., Sunn, W.A., and Simoni, R.D. (1992)J. Cell Biol. 117, 959–974.

    Article  PubMed  CAS  Google Scholar 

  72. Vollack, K.-U., Dittrich, B., Ferrer, A., Boronat, A., and Bach, T.J. (1994)J. Plant Physiol. 143, 479–487.

    CAS  Google Scholar 

  73. Arebalo, R.E., and Mitchell, Jr., E.D. (1984)Phytochemistry 23, 13–18.

    Article  CAS  Google Scholar 

  74. Ramachandra Reddy, A., and Das, V.S.R. (1986)Phytochemistry 25, 2471–2474.

    Article  Google Scholar 

  75. Ramachandra Reddy, A., and Das, V.S.R. (1987)New Phytol. 106, 457–464.

    Google Scholar 

  76. Schulze-Siebert, D., and Schultz, G. (1987)Plant Physiol. Biochem. 25, 145–153.

    CAS  Google Scholar 

  77. Bäuerle, R., Lütke-Brinkhaus, F., Ortmann, B., Berger, S., and Kleinig, H. (1990) Planta181, 229–233.

    Article  Google Scholar 

  78. Heintze, A., Görlach, J., Leuschner, C., Hoppe, P., Hagelstein, P., Schulze-Siebert, D., and Schultz, G. (1990)Plant Physiol. 93, 1121–1127.

    PubMed  CAS  Google Scholar 

  79. Soll, J., and Waegemann, K. (1993) Abstract No. 5.4.3-2,XV International Botanical Congress, Yokohama, Japan, August 28–September 3, 1993, Abstract Volume p. 132.

  80. Boronat, A., Balcells, L., Campos, N., Enjuto, M., Lumbreras, V., Marín, C., Arró, M., Becerra, B., and Ferrer, A. (1994) Abstract L2,2nd Symposium of the European Network on Plant Terpenoids, Strasbourg/Bischenberg, January 23–27, 1994.

  81. Jenkins, S., Callan, K., Loraine, A., Schmidt, D., and Gruissem, W. (1994) Abstract L3,2nd Symposium of the European Network on Plant Terpenoids, Strasbourg/Bischenberg, January 23–27, 1994.

  82. Weber, T., and Bach, T.J. (1994)Biochim. Biophys. Acta 1211, 85–96.

    PubMed  CAS  Google Scholar 

  83. Bach, T.J., Raudot, V., Vollack, K.-U., Weber, T., and Zeiler, S. (1994)Plant Physiol. Biochem. 32, 775–783.

    CAS  Google Scholar 

  84. Vollack, K.-U. (1994) Isolierung und Charakterisierung einer cDNA für die Acetoacetyl-CoA-Thiolase [EC 2.3.1.9] ausRaphanus sativus L. durch Komplementierung einerSaccharomyces cerevisiae-Mutane. Dissertation, Fakultät für Biound Geowissenschaften, Universität Karlsruhe, Germany.

    Google Scholar 

  85. van der Heijden, R., de Boer-Hlupá, V., Verpoorte, R., and Duine, J.A. (1994)Plant Cell Tissue Organ Cult. 38, 345–349.

    Article  Google Scholar 

  86. van der Heijden, R., Verpoorte, R., and Duine, J.A. (1994)Plant Physiol. Biochem. 32, 807–812.

    CAS  Google Scholar 

  87. McCaskill, D., and Croteau, R. (1993)Anal. Biochem. 215, 142–149.

    Article  PubMed  CAS  Google Scholar 

  88. Suga, T., Tange, K., Iccho, K., and Hirata, T. (1980)Phytochemistry 19, 67–70.

    Article  CAS  Google Scholar 

  89. Tange, K. (1981)Bull. Chem. Soc. Jpn. 54, 2763–2769.

    Article  CAS  Google Scholar 

  90. Anastasis, P., Freer, I., Picken, D., Overton, K., Sadler, I., and Singh, S.B. (1983)J. Chem. Soc. Chem. Commun., 1189–1191.

  91. Anastasis, P., Freer, I., Overton, K., Rycroft, D., and Singh, S.B. (1985)J. Chem. Soc. Chem. Commun., 148–149.

  92. Banerjii, A., and Chintalwar, G.J. (1989)Ind. J. Biochem. Biophys. 26, 394–396.

    Google Scholar 

  93. Weber, T., and Bach, T.J. (1993)Z. Naturforsch. C. 48, 444–450.

    CAS  Google Scholar 

  94. Wurtele, E.S., and Nicolau, B.J. (1990)Arch. Biochem. Biophys. 278, 179–186.

    Article  PubMed  CAS  Google Scholar 

  95. Wurtele, E.S., and Nicolau, B.J. (1992)Plant Physiol. 99, 1699–1703.

    PubMed  CAS  Google Scholar 

  96. Baldet, P., Alban, C., Axiotis, S., and Douce, R. (1992)Plant Physiol. 99, 450–455.

    PubMed  CAS  Google Scholar 

  97. Alban, C., Baldet, P., Axiotis, S., and Douce, R. (1993)Plant Physiol. 102, 957–965.

    PubMed  CAS  Google Scholar 

  98. Clauss, M., Motel, A., and Lichtenthaler, H.K. (1993)J. Plant Physiol. 141, 508–511.

    CAS  Google Scholar 

  99. Gerbling, H. (1993)Bot. Acta 106, 380–387.

    CAS  Google Scholar 

  100. Loreto, F., and Sharkey, T.D. (1993)Planta 189, 420–424.

    Article  CAS  Google Scholar 

  101. Fall, R., and Monson, R.K. (1992)Plant Physiol. 100, 987–992.

    PubMed  CAS  Google Scholar 

  102. Loreto, F., and Sharkey, T.D. (1993)Plant Cell Environm. 16, 563–570.

    Article  CAS  Google Scholar 

  103. Silver, G.M., and Fall, R. (1991)Plant Physiol. 96, 563–570.

    Google Scholar 

  104. Sanadze, G.A., Dzhaini, G.I. and Tevzadze, T.M. (1972)Sov. Plant Physiol. 19, 17–20.

    Google Scholar 

  105. Rasmussen, R.A., and Jones, C.A. (1973)Phytochemistry 12, 15–19.

    Article  CAS  Google Scholar 

  106. Mgaloblishvili, M.P., Khetsuriani, N.D., Kalandadze, A.N., and Sanadze, G.A. (1979)Sov. Plant Physiol. 25, 837–842.

    Google Scholar 

  107. Tingey, D.T., Evans, R., and Gumpertz, M. (1981)Planta 152, 565–570.

    Article  CAS  Google Scholar 

  108. Monson, R.K., Hills, A.J., Zimmermann, P.R., and Fall, R. (1991)Plant Cell Environm. 14, 517–523.

    Article  Google Scholar 

  109. Stone, B.G., Besse, T.J., Duane, W.C., Evans, C.D., and De-Master, E.G. (1993)Lipids 28, 705–708.

    Article  PubMed  CAS  Google Scholar 

  110. Reardon, J.E., and Abeles, R.H. (1986)Biochemistry 25, 5609–5616.

    Article  PubMed  CAS  Google Scholar 

  111. Muehlbacher, M., and Poulter, C.D. (1988)Biochemistry 27, 7315–7328.

    Article  PubMed  CAS  Google Scholar 

  112. Deneris, E.S., Stein, R.A., and Mead, J.F. (1985)J. Biol. Chem. 260, 1382–1385.

    PubMed  CAS  Google Scholar 

  113. Takahashi, I., and Ogura, K. (1981)J. Biochem. (Tokyo) 89, 1581–1587.

    CAS  Google Scholar 

  114. Fujii, H., Koyama, T., and Ogura, K. (1982)J. Biol. Chem. 257, 14610–14612.

    PubMed  CAS  Google Scholar 

  115. Fujii, H., Koyama, T., and Ogura, K. (1983)FEBS Lett. 161, 257–260.

    Article  PubMed  CAS  Google Scholar 

  116. Takatsuji, H., Nishino, T., Miki, I., and Katsuki, H. (1983)Biochem. Biophys. Res. Commun. 110, 187–193.

    Article  PubMed  CAS  Google Scholar 

  117. Fujisaki, S., Nishino, T. and Katsuki, H. (1986)J. Biochem. (Tokyo) 99, 1137–1146.

    CAS  Google Scholar 

  118. Fujisaki, S., Nishino, T., and Katsuki, H. (1986)J. Biochem. (Tokyo) 99, 1327–1337.

    CAS  Google Scholar 

  119. Seckler, B., and Poralla, K. (1986)Biochim. Biophys. Acta 881, 356–363.

    CAS  Google Scholar 

  120. Siebert, M., Bechtold, A., Melzer, M., May, U., Berger, U., Schröder, G., Schröder, J., Severin, K., and Heide, L. (1992)FEBS Lett. 307, 347–350.

    Article  PubMed  CAS  Google Scholar 

  121. Melzer, M., and Heide, L. (1994)Biochim. Biophys. Acta 1212, 93–102.

    PubMed  CAS  Google Scholar 

  122. Taylor, R.F. (1984)Microbiol. Rev. 48, 181–198.

    PubMed  CAS  Google Scholar 

  123. Zhou, D., and White, R.H. (1991)Biochem. J. 273, 627–634.

    PubMed  CAS  Google Scholar 

  124. Rohmer, M., Bisseret, P., and Sutter, B. (1992)Progr. Drug Res. 37, 271–285.

    Google Scholar 

  125. Rohmer, M., Knani, M., Simonin, P., Sutter, B., and Sahm, H. (1993)Biochem. J. 295, 517–524.

    PubMed  CAS  Google Scholar 

  126. Ourisson, G., and Rohmer, M. (1992) inRheinisch-Westfälische Akademie der Wissenschaften, Vorträge Nr. 395, pp. 21–34, Westdeutscher Verlag, Aachen.

    Google Scholar 

  127. Horbach, S., Sahm, H., and Welle, R. (1993)FEMS Microbiol. Lett. 111, 135–140 (1993).

    Article  PubMed  CAS  Google Scholar 

  128. Flesch, G., and Rohmer, M. (1988)Eur. J. Biochem. 175, 405–411.

    Article  PubMed  CAS  Google Scholar 

  129. Rohmer, M., Sutter, B., and Sahm, H. (1989)J. Chem. Soc. Chem. Commun., 1471–1472.

  130. Rohmer, M., Bisseret, M.P., and Sutter, B. (1991)Progr. Drug. Res. 37, 271–285.

    CAS  Google Scholar 

  131. Rohmer, M. (1993)Pure Appl. Chem. 65, 1293–1298.

    CAS  Google Scholar 

  132. Simonin, P., Jürgens, U.W., and Rohmer, M. (1992)Tetrahedron Lett. 33, 3629–3632.

    Article  CAS  Google Scholar 

  133. Stampf, P., Herrmann, D., Bisseret, P., and Rohmer, M. (1990)Tetrahedron 47, 7081–7090.

    Article  Google Scholar 

  134. Peiseler, B., and Rohmer, M. (1991)J. Chem. Soc. Perkin Trans. 1, 2449–2453.

    Article  Google Scholar 

  135. Hano, Y., Ayukawa, A., Nomura, T., and Ueda, S. (1994)Naturwissenschaften 81, 260–262.

    CAS  Google Scholar 

  136. Hano, Y., Ayukawa, A., Nomura, T., and Ueda, S. (1994)J. Am. Chem. Soc. 116, 4189–4193.

    Article  CAS  Google Scholar 

  137. Cartayrade, A., Schwarz, M., Jaun, B., and Arigoni, D. (1994) Abstract P1,2nd Symposium of the European Network on Plant Terpenoids, Strasbourg/Bischenberg, January 23–27, 1994.

  138. Flesch, V., Jacques, M., Cosson, L., Teng, B.P., Petiard, V., and Balz, J.P. (1992)Phytochemistry 31, 1941–1945.

    Article  CAS  Google Scholar 

  139. Schwarz, M. (1995) Dissertation Nr. 10951, Eidgenössische Technische Hochschule, pp. 84–171, Zürich, Switzerland.

  140. Soler, E., Clastre, M., Bantignies, B., Marigo, G., and Ambid, C. (1993)Planta 191, 324–329.

    Article  CAS  Google Scholar 

  141. Stivers, J.T., and Washabaugh, M.W. (1993)Biochemistry 32, 13472–13482.

    Article  PubMed  CAS  Google Scholar 

  142. Lee, T.C., and Langston-Unkefer, P.J. (1985)Plant Physiol. 79, 242–247.

    PubMed  CAS  Google Scholar 

  143. Miernyk, J.A. (1990) inPlant Physiology, Biochemistry and Molecular Biology (Dennis, D.T., and Turpin, D.H., eds.) pp. 77–100, Longman Scientific & Technical, Essex.

    Google Scholar 

  144. Kelley, P.M. (1989)Plant Mol. Biol. 13, 213–222.

    Article  PubMed  CAS  Google Scholar 

  145. Peschke, V.M., and Sachs, M.M. (1993)Mol. Gen. Genet. 240, 206–212.

    Article  PubMed  CAS  Google Scholar 

  146. Randall, D.D., and Miernyk, J.A. (1990) inMethods in Plant Biochemistry Vol. 3, Enzymes of Primary Metabolism (Lea, P.J., ed.) pp. 175–192, Academic Press, London.

    Google Scholar 

  147. Hoppe, P., Heintze, A., Riedel, A., Creutzer, C., and Schultz, G. (1993)Planta 190, 253–262.

    Article  CAS  Google Scholar 

  148. McHale, N.A., Hanson, K.R., and Zelitch, I. (1988)Plant Physiol. 88, 930–935.

    Article  PubMed  CAS  Google Scholar 

  149. Tse, J.M.-T., and Schloss, J.V. (1993)Biochemistry 32, 10398–10403.

    Article  PubMed  CAS  Google Scholar 

  150. Gutkowski, J.A., and Lienhard, G.E. (1976)J. Biol. Chem. 251, 671–684.

    Google Scholar 

  151. Kleinig, H. (1987) inThe Metabolism, Structure, and Function of Plant Lipids (Stumpf, P.K., Mudd, J.B., and Nes, W.D., eds.) pp. 37–43, Plenum Press, New York.

    Google Scholar 

  152. Lütke-Brinkhaus, F., and Kleinig, H. (1987)Planta 171, 406–411.

    Article  Google Scholar 

  153. Emmanuel, B., and Robblee, A.R. (1984)Int. J. Biochem. 16, 907–911.

    Article  PubMed  CAS  Google Scholar 

  154. Davis, A.R. (1978)Steroids 31, 593–600.

    Article  PubMed  CAS  Google Scholar 

  155. Halarnkar, P.P., Wakayama, E.J., and Bromquist, G.J. (1988)Phytochemistry 27, 997–999.

    Article  CAS  Google Scholar 

  156. Fulton, D.C., Kroon, P.A., Matern, U., Threlfall, D.R., and Whitehead, I.M. (1993)Phytochemistry 34, 139–145.

    Article  CAS  Google Scholar 

  157. Gölz, P., and Feierabend, J. (1993)Z. Naturforsch. C. 48, 886–895.

    Google Scholar 

  158. Preiss, M., and Schultz, G. (1994)Plant Physiol. 105 (Suppl.) 65.

    Google Scholar 

  159. Riou, C. (1994) Isolement et caractérisation de l'ADNc codant pour la mévalonate kinase d'Arabdopsis thaliana par complémentation chez la levureSaccharomyces cerevisiae. Thèse doctorale, Université de Poitiers, France.

    Google Scholar 

  160. Tanaka, R.D., Lee, L.-Y., Schafer, B.L., Kratunis, V.J., Mohler, W., Robinson, G.W., and Mosley, S.T. (1990)Proc. Natl. Acad. Sci. USA 87, 2872–2876.

    Article  PubMed  CAS  Google Scholar 

  161. Schafer, B.L., Bishop, R.W., Kratunis, V.J., Kalinowski, S.S., Mosley, S.T., Gibson, K.M., and Tanaka, R.D. (1992)J. Biol. Chem. 267, 13229–13238.

    PubMed  CAS  Google Scholar 

  162. Oulmouden, A., and Karst, F. (1991)Curr. Genet. 19, 9–14.

    Article  PubMed  CAS  Google Scholar 

  163. Biardi, L., Sreedhar, A., Zokaei, A., Vartak, N.B., Bozeat, R.L., Shakelford, J.E., Keller, G.-A., and Krisans, S.K. (1994)J. Biol. Chem. 269, 1197–1205.

    PubMed  CAS  Google Scholar 

  164. Albrecht, M., and Sandmann, G. (1994)Plant Physiol. 105, 529–534.

    PubMed  Google Scholar 

  165. Heintze, A., Riedel, A., Aydogdu, S., and Schultz, G. (1994)Plant Physiol. Biochem. 32, 791–797.

    CAS  Google Scholar 

  166. Swiezewska, E., Dallner, G., Andersson, B., and Ernster, L. (1993)J. Biol. Chem. 268, 1494–1499.

    PubMed  CAS  Google Scholar 

  167. Janiszowska, W. (1987)Phytochemistry 26, 1403–1407.

    Article  CAS  Google Scholar 

  168. Soll, J., Schultz, G., Joyard, J., Douce, R., and Block, M.A. (1985)Arch. Biochem. Biophys. 238, 290–299.

    Article  PubMed  CAS  Google Scholar 

  169. Nes, W.R., and Nes, W.D. (1980)Lipids in Evolution, Plenum Press, New York.

    Google Scholar 

  170. Nes, W.D., and Venkatramesh, M. (1994) inIsopentenoids and Other Natural Products: Evolution and Function, (Nes, W.D., ed.), ACS Symposium Series, 562, 85–99, American Chemical Society, Washington DC.

    Google Scholar 

  171. Morden, C.W., Delwiche, C.F., Kuhsel, M., and Palmer, J.D. (1992)BioSystems 28, 75–90.

    Article  PubMed  CAS  Google Scholar 

  172. Cavalier-Smith, T. (1992)BioSystems 28, 91–106.

    Article  PubMed  CAS  Google Scholar 

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  1. C.N.R.S.-I.B.M.P., Département d'Enzymologie Cellulaire et Moléculaire, Institut de Botanique, Université Louis Pasteur, 28 rue Goethe, F-67083, Strabourg, Cédex, France

    Thomas J. Bach

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Bach, T.J. Some new aspects of isoprenoid biosynthesis in plants—A review. Lipids 30, 191–202 (1995). https://doi.org/10.1007/BF02537822

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  • DOI: https://doi.org/10.1007/BF02537822

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