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Effect of dietary palm oil and its fractions on rat plasma and high density lipoprotein lipids

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Lipids

Abstract

Male Sprague Dawley rats were fed semipurified diets containing 20% fat for 15 weeks. The dietary fats were corn oil, soybean oil, palm oil, palm olein and palm stearin. No differences in the body and organ weights of rats fed the various diets were evident. Plasma cholesterol levels of rats fed soybean oil were significantly lower than those of rats fed corn oil, palm oil, palm olein or palm stearin. Significant differences between the plasma cholesterol content of rats fed corn oil and rats fed the three palm oils were not evident. HDL cholesterol was raised in rats fed the three palm oil diets compared to the rats fed either corn oil or soybean oil. The cholesterol-phospholipid molar ratio of rat platelets was not influenced by the dietary fat type. The formation of 6-keto-PGF1α was significantly enhanced in palm oil-fed rats compared to all other dietary treatments. Fatty acid compositional changes in the plasma cholesterol esters and plasma triglycerides were diet regulated with significant differences between rats fed the polyunsaturated corn and soybean oil compared to the three palm oils.

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Abbreviations

CO:

corn oil

HDL:

high density lipoprotein

HMG-CoA:

hydroxymethylglutaryl coenzyme A

PO:

palm oil

POL:

palm olein

PGI2 :

prostacyclin I2

PS:

palm stearin

PUFA:

polyunsaturated fatty acid

SBO:

soybean oil

References

  1. Goodnight, S.H., Harris, W.S., Connor, W.E., and Illingworth, D.R. (1982)Arteriosclerosis 2, 87–113.

    PubMed  CAS  Google Scholar 

  2. Blaton, V., De Buyzere, M., Declerq, B., Pracetyo, A., Vanderkelen, G. Delanghe, J., and Spincemaille, J. (1984)Atherosclerosis 53, 9–20.

    Article  PubMed  CAS  Google Scholar 

  3. Jackson, R.L., Taunton, O.D., Morissett, J.D., and Gotto, A.M. (1978)Circulation Res. 42, 447–453.

    PubMed  CAS  Google Scholar 

  4. Keys, A. (1970)Circulation 41 (Suppl. 1), 1–211.

    Google Scholar 

  5. Grundy, S.M. (1986)N. Engl. J. Med. 314, 745–748.

    Article  PubMed  CAS  Google Scholar 

  6. Grundy, S.M., Florentin, L., Nix, D., and Whelan, M.F. (1988)Am. J. Clin. Nutr. 47, 965–969.

    PubMed  CAS  Google Scholar 

  7. Mattson, F.M., and Grundy, S.M. (1985)J. Lipid Res. 26, 194–202.

    PubMed  CAS  Google Scholar 

  8. Grundy, S.M., and Vega, G.L. (1988)Am. J. Clin. Nutr. 47, 822–824.

    PubMed  CAS  Google Scholar 

  9. Anonymous (1987)Nutrition Reviews 45, 205–207.

    Google Scholar 

  10. Hornstra, G. (1987)Agents and Action 22, 377–378.

    Article  Google Scholar 

  11. Berger, K.G. (1981)Food Uses of Palm Oil, PORIM Occasional Paper, No. 2, PORIM, Malaysia.

    Google Scholar 

  12. Tan, B.K., and Oh, F.C.H. (1981)Oleins and Stearins from Malaysian Palm Oil-Chemical and Physical Characteristics, PORIM Technology No. 4, PORIM, Malaysia.

    Google Scholar 

  13. Carlson, K. (1973)J. Clin. Pathol. 26 (Suppl. 5), 32–37.

    Google Scholar 

  14. Warnick, G.R., Bendersom J., and Albers, J.J. (1982)Clin. Chem. 28 1379–1388.

    PubMed  CAS  Google Scholar 

  15. Folch, J., Lees, M., and Sloane-Stanley, G.H. (1957)J. Biol. Chem. 226, 497–509.

    PubMed  CAS  Google Scholar 

  16. Khor, H.T., and Oo., K.C. (1984)Phytochemistry 23, 1577–1581.

    Article  Google Scholar 

  17. Marsh, J.B., and Weinstein, D.B. (1966)J. Lipid Res. 7, 574–576.

    PubMed  CAS  Google Scholar 

  18. Rouser, G., Siakatos, A.N., and Fleischer, S. (1970)Lipids 5, 494–496.

    Article  PubMed  CAS  Google Scholar 

  19. Aster, R.H., and Jandl, J.H. (1984)J. Clin. Invest. 43, 843–855.

    Google Scholar 

  20. Rand, M.L., Hennissen, A.A.H.M., and Hornstra, G. (1986)Atherosclerosis 62, 265–275.

    Article  Google Scholar 

  21. Lowry, O.H., Rosebrough, N.J., Farr, A.L., and Randall, R.J. (1951)J. Biol. Chem. 193, 265–275.

    PubMed  CAS  Google Scholar 

  22. Carroll, K.K., and Kohr, H.T. (1971)Lipids 6, 415–420.

    Article  PubMed  CAS  Google Scholar 

  23. Khor, H.T., and Tan, H.L. (1981)J. Sci. Food Agric. 32, 399–402.

    Article  CAS  Google Scholar 

  24. Jacobsberg, B., Deldima, P., and Gapor, A.B. (1978)Oleagineux 28, 25–32.

    Google Scholar 

  25. Kris-Etherton, P.M., Ho, C.Y., and Fosmire, M.A. (1984)J. Nutr. 114, 1675–1682.

    PubMed  CAS  Google Scholar 

  26. Sugano, M., Ishida, T., and Koba, K. (1988)J. Nutr. 118, 548–554.

    PubMed  CAS  Google Scholar 

  27. Qureshi, A., Burger, W.C., Peterson, D.M., and Elson, C.E. (1986)J. Biol. Chem. 261, 10544–10550.

    PubMed  CAS  Google Scholar 

  28. Dunn, G.D., Wilcox, H.G., and Heimberg, M. (1975)Lipids 10, 773–782.

    Article  PubMed  CAS  Google Scholar 

  29. Barter, P.J., Hopkins, G.J., and Calvert, G.D. (1982)Biochem. J. 208, 1–7.

    PubMed  CAS  Google Scholar 

  30. Oschry, Y., and Eisenberg, S. (1982)J. Lipid Res. 23, 1099–1106.

    PubMed  CAS  Google Scholar 

  31. Hotsmark, A.T., Spydevold, O., and Lystad, E. (1982)Lipids 17, 489–499.

    Google Scholar 

  32. Hotsmark, A.T., Spydevold, O., and Eilertsen, E. (1980)Artery 7, 367–383.

    Google Scholar 

  33. Feldman, E.B., Russell, B.S., Schnare, F.H., Miles, B.C., Doyle, E.A., and Moretti-Rojas, I. (1979)J. Nutr. 109, 2226–2236.

    PubMed  CAS  Google Scholar 

  34. Hornstra, G. (1982) inDietary Fats, Prostanoids and Arterial Thrombosis, pp. 136–166, Martinus Nijhoff, The Hague.

    Google Scholar 

  35. Rand, M.L., Hennissen, A.A.H.M., and Hornstra, G. (1988)Lipids 23, 1019–1023.

    Article  PubMed  CAS  Google Scholar 

  36. McGuire, J.C., and Sun, F.F. (1980)Adv. Prost. Thrombox. Res. 8, 1665–1667.

    CAS  Google Scholar 

  37. Galli, C., Agradi, E., Petroni, A., and Tremoli, E. (1981)Lipids 16, 165–172.

    PubMed  CAS  Google Scholar 

  38. Spector, A.A., Hoak, J.C., Fry, G.L., Denning, G.M., Stoll, L.L. and Smith, J.B. (1980)J. Clin. Invest. 65, 1003–1012.

    Article  PubMed  CAS  Google Scholar 

  39. Nordøy, A., Svennson, B., and Hoak, J.C. (1979)Eur. J. Clin. Invest. 9, 5–10.

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Palm Oil Research Institute of Malaysia (PORIM), P.O. Box 10620, 50720, Kuala Lumpur, Malaysia

    Kalyana Sundram & Augustine S. H. Ong

  2. Department of Biochemistry, University Malaya, Kuala Lumpur, Malaysia

    Hun Teik Khor

Authors
  1. Kalyana Sundram
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  2. Hun Teik Khor
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  3. Augustine S. H. Ong
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Sundram, K., Khor, H.T. & Ong, A.S.H. Effect of dietary palm oil and its fractions on rat plasma and high density lipoprotein lipids. Lipids 25, 187–193 (1990). https://doi.org/10.1007/BF02535746

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  • DOI: https://doi.org/10.1007/BF02535746

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