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Digestion of butyrate glycerides by pancreatic lipase

  • Published:
Lipids

Abstract

The racemic triglycerides, glyceryl-1-palmitate-2,3-dibutyrate (PBB), glyceryl-1-butyrate-2,3-dipalmitate (PPB), glyceryl-2-butyrate-1,3-dipalmitate (PBP), and the diglyceride, racemic glyceryl-1-palmitate-3-butyrate (P-B) were synthesized and digested with pancreatic lipase. Each triglyceride was mixed with equimolar amounts of triolein (OOO) prior to incubation.

The following order of digestion rates was observed: PBB>PPB>PBP>P-B. There was no evidence for short-chain fatty acid specificity; however the triglycerides containing butyric acid were hydrolyzed more rapidly than OOO. Based upon the fatty acid composition of partial glycerides, digestion of butyrate glycerides was not a simple phenomenon. For example, in the digestion of PBB, butyric acid accumulated faster than palmitic acid in the diglycerides, and monobutyrin was found to accumulate when the diglyceride, P-B, was digested. As evidenced by the fatty acid composition of the monoglycerides, positional specificity of pancreatic lipase was always maintained.

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References

  1. Jensen, R. G., J. Dairy Sci.47, 210–215 (1964).

    CAS  Google Scholar 

  2. Entressangles, B., L. Pasero, P. Savary, L. Sarda and P. Desnuelle, Bull. Soc. Chim. Biol.43, 581–591 (1961).

    PubMed  CAS  Google Scholar 

  3. Jensen, R. G., J. Sampugna, R. M. Parry Jr. and T. L. Forster, J. Dairy Sci.45, 842–847 (1962).

    CAS  Google Scholar 

  4. Jensen, R. G., J. Sampugna, R. L. Pereira, R. C. Chandan and K. M. Shahani, Ibid.47, 1012–1013 (1964).

    CAS  Google Scholar 

  5. Jensen, R. G., J. Sampugna and R. L. Pereira, Ibid.47, 727–732 (1964).

    CAS  Google Scholar 

  6. Jensen, R. G., T. A. Marks, J. Sampugna, J. G. Quinn and D. L. Carpenter, Lipids1, 451–452 (1967).

    Article  Google Scholar 

  7. Mattson, F. H., and R. A. Volpenhein, J. Lipid Research3, 281–296 (1962).

    CAS  Google Scholar 

  8. Quinn, J. G., J. Sampugna and R. G. Jensen, JAOCS44, 439–442 (1967).

    CAS  Google Scholar 

  9. Krabisch, L., and B. Borgström, J. Lipid Research6, 156–157 (1965).

    CAS  Google Scholar 

  10. Sampugna, J., R. E. Pitas and R. G. Jensen, J. Dairy Sci.49, 1462–1463 (1967).

    Google Scholar 

  11. Sampugna, J., R. G. Jensen, R. M. Parry Jr. and C. F. Krewson, JAOCS41, 132–133 (1964).

    CAS  Google Scholar 

  12. Harper, W. J., D. P. Schwartz and I. S. El-Hagarawy, J. Dairy Sci.39, 46–50 (1956).

    Article  CAS  Google Scholar 

  13. Gander, G. W., R. G. Jensen and J. Sampugna, Ibid.45, 323–328 (1962).

    CAS  Google Scholar 

  14. Association of Official Agricultural Chemists. “Official and Tentative Methods of Analysis,” 9th ed., Washington, D.C., 1960, p. 365.

  15. Jensen, R. G., and G. W. Gander, J. Dairy Sci.,42, 1235–1236 (1959).

    CAS  Google Scholar 

  16. Pereira, R. L., “A Study of the Mechanism of Pancreatic Lipase,” Ph.D. Thesis, University of Connecticut (1967).

  17. Nichaman, M. Z., C. C. Sweeley, N. M. Oldham and R. E. Olson, J. Lipid Research4, 484–485 (1963).

    CAS  Google Scholar 

  18. Schønheyder, F., and K. Volqvartz, Biochim. Biophys. Acta.15, 288–290 (1954).

    Article  PubMed  Google Scholar 

  19. Clement, G., J. Clement and J. Bezard, Arch. Sci. Physiol.16, 213–225 (1962).

    CAS  Google Scholar 

  20. Thomas, A. E. III, J. E. Scharoun and Helma Ralston, JAOCS42, 789–792 (1965).

    CAS  Google Scholar 

  21. Benzonana, G., and P. Desnuelle, Biochim. Biophys. Acta.105, 121–136 (1965).

    PubMed  CAS  Google Scholar 

  22. Jensen, R. G., J. Sampugna, R. M. Parry Jr. and K. M. Shahani, J. Dairy Sci.46, 907–910 (1963).

    Article  CAS  Google Scholar 

  23. Coleman, M. H., JAOCS40, 568–571 (1963).

    CAS  Google Scholar 

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Author information

Author notes

  1. J. G. Quinn

    Present address: Worchester Foundation for Experimental Biology, Shrewsbury, Mass

  2. D. L. Carpenter

    Present address: Department of Dairy Science, University of Maryland, College Park

Authors and Affiliations

  1. Department of Animal Industries, University of Connecticut, Storrs, Connecticut

    J. Sampugna, J. G. Quinn, R. E. Pitas, D. L. Carpenter & R. G. Jensen

Authors
  1. J. Sampugna
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  2. J. G. Quinn
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  3. R. E. Pitas
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  4. D. L. Carpenter
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  5. R. G. Jensen
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Additional information

Scientific contribution No. 245, Agricultural Experiment Station, University of Connecticut, Storrs.

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Sampugna, J., Quinn, J.G., Pitas, R.E. et al. Digestion of butyrate glycerides by pancreatic lipase. Lipids 2, 397–402 (1967). https://doi.org/10.1007/BF02531853

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  • DOI: https://doi.org/10.1007/BF02531853

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