Abstract
A general theory for the design of apparatus for the low temperature drying of frozen tissues has been developed. Using this theory it is possible to compute drying rates for different materials in different apparatuses and to design an apparatus suitable for the required purpose. It is shown that for the drying of animal tissues in the laboratory, where the area is small, the requirements of the apparatus are not particularly critical. The same theory applied to the drying of biologicals and plasma indicates that the design is exceedingly critical and suggests directions in which existing apparatus might be modified.
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Aided by a grant from the Wallace C. and Clara A. Abbott Memorial Fund of the University of Chicago and from the Commonwealth Fund of New York.
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Stephenson, J.L. Theory for the design of apparatus for drying frozen tissues. Bulletin of Mathematical Biophysics 16, 23–43 (1954). https://doi.org/10.1007/BF02481810
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DOI: https://doi.org/10.1007/BF02481810