Abstract
A comprehensive numerical model, based on the finite-element method, for the continuous simulation of the complete cardiac cycle is presented. The model uses real, measuredin vivo, three-dimensional geometry of the ventricle, and accounts for the anisotropy of the ventricular wall, the large deformations it undergoes during the cardiac cycle, the material nonlinearity of the myocardium and its mechanical activation. The simulation process is carried out incrementally while adjusting the mechanical activation for each increment so as to produce the same change in cavity volume as that measured experimentally. A detailed analysis of a complete cycle of the canine heart is presented in Part 2 of the paper.
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Perl, M., Horowitz, A. & Sideman, S. Comprehensive model for the simulation of left ventricle mechanics. Med. Biol. Eng. Comput. 24, 145–149 (1986). https://doi.org/10.1007/BF02443927
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DOI: https://doi.org/10.1007/BF02443927