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Digitalis toxicity in infants and children

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Summary

There is a narrow difference between the therapeutic and toxic ranges of cardiac glycosides. The availability in the past decade of radioimmunoassays for accurate measurement of these glycosides has resulted in an improved understanding of their pharmacokinetics and clinical use. Despite these advances, however, digitalis toxicity is still a common problem in infants and children.

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Authors and Affiliations

  1. Section of Pediatric Cardiology, College of Medicine, University of Illinois at Chicago, Health Sciences Center, Chicago, Illinois, USA

    Alois R. Hastreiter & Ronald L. van der Horst

  2. Department of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Health Sciences Center, Chicago, Illinois, USA

    Elizabeth Chow-Tung

Authors
  1. Alois R. Hastreiter
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  2. Ronald L. van der Horst
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  3. Elizabeth Chow-Tung
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Supported in part by the University of Illinois Foundation Goodenberger Medical Research Grant 2-6-46856.

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Hastreiter, A.R., van der Horst, R.L. & Chow-Tung, E. Digitalis toxicity in infants and children. Pediatr Cardiol 5, 131–148 (1984). https://doi.org/10.1007/BF02424966

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