Summary
Rat pituitary MAO activity was reduced by constant darkness and by additions of melatonin in vitro and was increased by constant light and by pinealectomy. Hypothalamic MAO activity followed the same pattern but was less dramatically affected. The data suggest that MAO may be a target enzyme for melatonin.
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This research was sponsored by Utah State University Research Project U-300, and U.S. Atomic Energy Commission Grant No. AT(11-1)-1602.
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Urry, R.L., Ellis, L.C. Monoamine oxidase activity of the hypothalamus and pituitary: Alterations after pinealectomy, changes in photoperiod, or additions of melatonin in vitro. Experientia 31, 891–892 (1975). https://doi.org/10.1007/BF02358834
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DOI: https://doi.org/10.1007/BF02358834