Abstract
Psychiatric symptoms were investigated and compared in 95 patients with Alzheimer type dementia (DAT) and in 39 patients with Parkinson's disease with dementia (PD-D). The diagnosis of the dementia and psychiatric disorders was based on DSM III R criteria; dementia stage was assessed using the Clinical Dementia Rating Scale (CDR). PD-D were significantly older than DAT patients. Delirium was more frequent in the advanced stages of both PD-D and DAT, being mainly of the hypoactive type in PD-D and the hyperactive type in DAT. Delusions and hallucinations predominated in the early CDR stages of both illnesses and did not differ between groups; the same was true for depression. The results revealed different psychopathological profiles in DAT and PD-D patients.
Sommario
In questo studio sono stati valutati e confrontati i disturbi psichiatrici di 95 pazienti affetti da demenza a tipo Alzheimer (DAT) e di 39 parkinsoniani dementi (PD-D). La diagnosi di demenza e di disturbi psichiatrici è stata eseguita basandosi sui criteri del DSM III R, il livello di demenza è stato valutato secondo la Clinical Dementia Rating Scale (CDR). I PD-D erano significativamente più anziani dei DAT. Il delirium era significativamente più frequente negli stadi più avanzati, sia tra i PD-D che tra i DAT, manifestandosi prevalentemente come ipoattivo tra i PD-D, come iperattivo tra i DAT. I deliri e le allucinazioni predominavano ai livelli più bassi di CDR in entrambe le patologie, non differendo tra i due gruppi. Lo stesso avveniva per la depressione. I risultati hanno rivelato profili psicopatologici differenti nei PD-D e nei DAT.
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Soliveri, P., Zappacesta, M.B., Austoni, L. et al. Differing patterns of psychiatric impairment in Alzheimer and demented parkinsonian patients. Ital J Neuro Sci 15, 407–411 (1994). https://doi.org/10.1007/BF02339904
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DOI: https://doi.org/10.1007/BF02339904