Summary
Two oxidation procedures for the synthesis of silicabased aliphatic sulfonic acid cation-exchangers for HPLC are described. Several reaction conditions for oxidizing a terminal-bonded thiol with organic peroxides are provided along with their yields, capacities, reproducibility, and chromatographic behavior. Also, three methods for determining exchange capacity are discussed, and their relationship to the capacity factors of charged solutes is compared. The maximum capacity determined by the titration of the bonded silica was 0.34 meq/gram. The general problems of synthesizing cation-exchangers, measuring their efficiencies and exchange capacities, and evaluating their overall performances are outlined.
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References
G. Cox, C. Loscombe, M. Slucutt, K. Sugden, J. Upfield, J. Chromatogr.,117, 269 (1976).
P. Asmus, Chow-Eng Low, M. Novotny, J. Chromatogr.,119, 25 (1976).
P. Asmus, Chow-Eng Low, M. Novotny, J. Chromatogr.,123, 109 (1976).
N. Weigand, I. Sebestian, I. Halasz, J. Chromatogr.,102, 325 (1974).
B. Wheals, J. Chromatogr.,177, 263 (1979).
J. Crowthers, P. Griffiths, S. Fazio, J. Magram, R. Hartwick, J. Chromatogr. Sci., in press.
D. S. Tarbell, “Organic Sulfur Compounds”, Vol. I, Plenum Press, New York, 1961; p. 97.
J. E. Hesse, F. K. Truley, Chem. Ind. (London)16, 680 (1965).
J. S. Showell, J. R. Russell, D. Swern, J. Org. Chem.,27, 2853 (1962).
D. Swern, “Organic Peroxides”, Vol. 1, J. Wiley and Sons, Inc., New York, 1971.
B. Phillips, P. Starcher, B. Ash, J. Org. Chem.,23, 1823 (1959).
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Fazio, S.D., Crowther, J.B. & Hartwick, R.A. The synthesis and characterization of aliphatic sulfonic acid cation exchangers for HPLC. Chromatographia 18, 216–220 (1984). https://doi.org/10.1007/BF02276736
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DOI: https://doi.org/10.1007/BF02276736