Summary
The acute clinical picture and long-term prognosis of 160 patients with Reiter's disease (RD), and 144 patients with reactive arthritis triggered by yersinia infection (YA), was analysed. Most of the patients with RD were men, while YA was as common among male and female patients. YA manifested in a third of patients as incomplete or complete RD. The long-term prognosis in RD was less favourable than in YA. Recurrent arthritis, development of chronic destructive arthritis and radiologic sacroiliitis were more frequent in RD than in YA. The presence of HLA-B27 was the major factor determining extra-articular inflammatory symptoms and the development of chronic problems.
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Bolton, R.P., Wood, G.M., Losowsky, M.S. Acute arthritis associated with clostridium difficile colitis. Br Med J 1981, 283, 1023–1024.
Anonymous. Is Reiter's syndrome caused by chlamydia? Lancet 1985, 1, 317–319.
Keat, A. Reiter's syndrome and reactive arthritis in perspective. N Engl J Med 1983, 309, 1606–1615.
Leirisalo, M., Skylv, G., Kousa, M., Voipio-Pulkki, L.-M., Suoranta, H., Nissilä, M., Hvidman, L., Nielsen, E.D., Svejgaard, A., Tiilikainen, A., Laitinen, O. Follow-up study on patients with Reiter's disease and reactive arthritis, with special reference to HLA-B27. Arthritis Rheum 1982, 25, 249–259.
Olhagen, B. Postinfective or reactive arthritis. Scand J Rheumatol 1980, 9, 193–202.
Doury, P., Eulry, F., Pattin, S.. Aspects cliniques des arthrites réactionelles à chlamydia. Rev Rhum 1983, 50, 753–757.
Ahvonen, P. Human yersiniosis in Finland. II. Clinical features. Ann Clin Res 1972, 4, 39–48.
Leino, R., Kalliomäki, J.L. Yersiniosis as an internal disease. Ann Intern Med 1974, 81, 458–461.
Marsal, L., Winblad, S., Wollheim, F.A. Yersinia enterocolitica arthritis in southern Sweden: a four-year follow-up study. Br Med J 1981, 283, 101–103.
Keat, A.C., Maini, R.N., Pegrum, G.D., Scott, J.T. The clinical features and HLA associations of reactive arthritis associated with non-gonococcal urethritis. Q J Med 1979, 190, 323–342.
Fox, R., Calin, A., Gerber, R.C., Gibson, D. The chronicity of symptoms and disability in Reiter's syndrome. Ann Intern Med 1979, 91, 190–193.
Sairanen, E., Paronen, I., Mähönen, H. Reiter's syndrome: a follow-up study. Acta Med Scand 1969, 185, 57–63.
Csonka, G.W. Recurrent attacks in Reiter's disease. Arthritis Rheum 1960, 3, 164–169.
Kousa, M. Clinical observations on Reiter's disease with special reference to the venereal and non-venereal aetiology. Acta Dermato-Venereol 1978, 58, suppl. 81, 1–36.
Kalliomäki, J.L., Leino, R., Follow-up studies of joint complications in yersiniosis. Acta Med Scand 1979, 205, 521–525.
Aho, K., Ahvonen, P., Lassus, A., Sievers, K., Tiilikainen, A. Yersinia arthritis and related diseases: clinical and immunogenetic implications. In: Infection and Immunology in Rheumatic Diseases. Editor: Dumonde, D.C. Oxford, Blackwell, 1976, 341–344.
Amor, B. Etudes familiales des arthrites réactionelles. Rev Rhum 1983, 50, 771–775.
Calin, A. Ankylosing spondylitis. Clin Rheum Dis 1985, 11, 41–60.
Marks, J.S., Holt, P.J.L. The natural history of Reiter's disease — 21 years of observations. Q J Med 1986, 231, 685–697.
Dequeker, J., Jamar, R., Walravens, M. HLA-B27, arthritis and Yersinia enterocolitica infection. J Rheumatol 1980, 7, 706–710.
Popert, A.J., Gill, A.J., Laird, S.M. A prospective study of Reiter's syndrome. An interim report on the first 82 cases. Br J Vener Dis 1964, 40, 160–165.
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Leirisalo-Repo, M., Skylv, G. & Kousa, M. Follow-up study of reiter's disease and reactive arthritis. Factors influencing the natural course and the prognosis. Clin Rheumatol 6 (Suppl 2), 73–82 (1987). https://doi.org/10.1007/BF02203388
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DOI: https://doi.org/10.1007/BF02203388