Skip to main content
Log in

Follow-up study of reiter's disease and reactive arthritis. Factors influencing the natural course and the prognosis

  • Sero-Negative Arthritis
  • Published:
Clinical Rheumatology Aims and scope Submit manuscript

Summary

The acute clinical picture and long-term prognosis of 160 patients with Reiter's disease (RD), and 144 patients with reactive arthritis triggered by yersinia infection (YA), was analysed. Most of the patients with RD were men, while YA was as common among male and female patients. YA manifested in a third of patients as incomplete or complete RD. The long-term prognosis in RD was less favourable than in YA. Recurrent arthritis, development of chronic destructive arthritis and radiologic sacroiliitis were more frequent in RD than in YA. The presence of HLA-B27 was the major factor determining extra-articular inflammatory symptoms and the development of chronic problems.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Bolton, R.P., Wood, G.M., Losowsky, M.S. Acute arthritis associated with clostridium difficile colitis. Br Med J 1981, 283, 1023–1024.

    Google Scholar 

  2. Anonymous. Is Reiter's syndrome caused by chlamydia? Lancet 1985, 1, 317–319.

  3. Keat, A. Reiter's syndrome and reactive arthritis in perspective. N Engl J Med 1983, 309, 1606–1615.

    Google Scholar 

  4. Leirisalo, M., Skylv, G., Kousa, M., Voipio-Pulkki, L.-M., Suoranta, H., Nissilä, M., Hvidman, L., Nielsen, E.D., Svejgaard, A., Tiilikainen, A., Laitinen, O. Follow-up study on patients with Reiter's disease and reactive arthritis, with special reference to HLA-B27. Arthritis Rheum 1982, 25, 249–259.

    Google Scholar 

  5. Olhagen, B. Postinfective or reactive arthritis. Scand J Rheumatol 1980, 9, 193–202.

    Google Scholar 

  6. Doury, P., Eulry, F., Pattin, S.. Aspects cliniques des arthrites réactionelles à chlamydia. Rev Rhum 1983, 50, 753–757.

    Google Scholar 

  7. Ahvonen, P. Human yersiniosis in Finland. II. Clinical features. Ann Clin Res 1972, 4, 39–48.

    Google Scholar 

  8. Leino, R., Kalliomäki, J.L. Yersiniosis as an internal disease. Ann Intern Med 1974, 81, 458–461.

    Google Scholar 

  9. Marsal, L., Winblad, S., Wollheim, F.A. Yersinia enterocolitica arthritis in southern Sweden: a four-year follow-up study. Br Med J 1981, 283, 101–103.

    Google Scholar 

  10. Keat, A.C., Maini, R.N., Pegrum, G.D., Scott, J.T. The clinical features and HLA associations of reactive arthritis associated with non-gonococcal urethritis. Q J Med 1979, 190, 323–342.

    Google Scholar 

  11. Fox, R., Calin, A., Gerber, R.C., Gibson, D. The chronicity of symptoms and disability in Reiter's syndrome. Ann Intern Med 1979, 91, 190–193.

    Google Scholar 

  12. Sairanen, E., Paronen, I., Mähönen, H. Reiter's syndrome: a follow-up study. Acta Med Scand 1969, 185, 57–63.

    Google Scholar 

  13. Csonka, G.W. Recurrent attacks in Reiter's disease. Arthritis Rheum 1960, 3, 164–169.

    Google Scholar 

  14. Kousa, M. Clinical observations on Reiter's disease with special reference to the venereal and non-venereal aetiology. Acta Dermato-Venereol 1978, 58, suppl. 81, 1–36.

    Google Scholar 

  15. Kalliomäki, J.L., Leino, R., Follow-up studies of joint complications in yersiniosis. Acta Med Scand 1979, 205, 521–525.

    Google Scholar 

  16. Aho, K., Ahvonen, P., Lassus, A., Sievers, K., Tiilikainen, A. Yersinia arthritis and related diseases: clinical and immunogenetic implications. In: Infection and Immunology in Rheumatic Diseases. Editor: Dumonde, D.C. Oxford, Blackwell, 1976, 341–344.

    Google Scholar 

  17. Amor, B. Etudes familiales des arthrites réactionelles. Rev Rhum 1983, 50, 771–775.

    Google Scholar 

  18. Calin, A. Ankylosing spondylitis. Clin Rheum Dis 1985, 11, 41–60.

    Google Scholar 

  19. Marks, J.S., Holt, P.J.L. The natural history of Reiter's disease — 21 years of observations. Q J Med 1986, 231, 685–697.

    Google Scholar 

  20. Dequeker, J., Jamar, R., Walravens, M. HLA-B27, arthritis and Yersinia enterocolitica infection. J Rheumatol 1980, 7, 706–710.

    Google Scholar 

  21. Popert, A.J., Gill, A.J., Laird, S.M. A prospective study of Reiter's syndrome. An interim report on the first 82 cases. Br J Vener Dis 1964, 40, 160–165.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Leirisalo-Repo, M., Skylv, G. & Kousa, M. Follow-up study of reiter's disease and reactive arthritis. Factors influencing the natural course and the prognosis. Clin Rheumatol 6 (Suppl 2), 73–82 (1987). https://doi.org/10.1007/BF02203388

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02203388

Key Words

Navigation