Skip to main content
Log in

Etiology of individual differences in reading performance: A test of sex limitation

  • Published:
Behavior Genetics Aims and scope Submit manuscript

Abstract

To test the hypothesis that the etiology of individual differences in reading performance differs in males and females, reading performance data from twin pairs tested in the Colorado Learning Disabilities Research Center were fitted to structural equation models of sex limitation. The sample included 513 pairs of twins in which at least one member of each pair has a positive school history of reading problems [228 monozygotic (MZ), 176 same-sex dizygotic (DZ), and 109 opposite-sex DZ pairs] and 302 matched control pairs [148 MZ, 98 same-sex DZ, and 56 opposite-sex DZ pairs]. Estimates of the genetic correlation between performance in males and females were obtained by analysis of data from both same-sex and opposite-sex twin pairs (Neale and Cardon, 1992). The full model fit the data well χ2=17,74, df=16,p=0.340), and the resulting genetic parameter estimates were highly similar in males and females in both the proband and the control samples. The correlations between genetic influences in males and females do not differ among groups (change in χ2=0.95, df=1,p≥0.25), and the resulting pooled estimate is about .5. Thus, results of this analysis suggest that the etiology of individual differences in reading performance may differ to some extent in males and females.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Ackerman, P. T., and Dykman, R. A. (1993). Gender and rading disability.J. Learn. Disabil. 26:498.

    Google Scholar 

  • DeFries, J. C., and Decker, S. N. (1982). Genetic aspects of reading disability: A family study. In: R. N. Malatesha and P. G. Aaron (eds),Reading Disorders: Varieties and Treatments, Academic Press, New York, pp. 255–279.

    Google Scholar 

  • DeFries, J. C., and Fulker, D. W. (1985). Multiple regression analysis of twin data.Behav. Genet. 15:467–473.

    Google Scholar 

  • DeFries, J. C., and Gillis, J. J. (1991). Etiology of reading deficits in learning disabilities: Quantitative genetic analysis. In: J. E. Obrzut and G. W. Hynd (eds.),Neuropsychological Foundations of Learning Disabilities: A Handbook of Issues, Methods and Practice, Academic Press, Orlando, FL, pp. 29–47.

    Google Scholar 

  • DeFries, J. C., and Gillis, J. J. (1993). Genetics of reading disability. In R. Plomin and G. E. McClearn (eds.),Nature Nurture & Psychology, American Psychological Association, Washington, DC, pp. 121–145.

    Google Scholar 

  • DeFries, J. C., Fulker, D. W., and LaBuda, M. C. (1987). Evidence for a genetic aetiology in reading disability of twins.Nature 329:537–539.

    Google Scholar 

  • DeFries, J. C., Olson, R. K., Pennington, B. F., and Smith, S. D. (1991). Colorado reading project: Past, present, and future.Learn. Disabil. 2:37–46.

    Google Scholar 

  • DeFries, J. C., Gillis, J. J., and Wadsworth, S. J. (1993). Genes and genders: A twin study of reading disability. In A. M. Galaburda (ed.),Dyslexia and Development. Neurobiological Aspects of Extra-Ordinary Brains Harvard University Press, Cambridge, MA, pp. 187–204.

    Google Scholar 

  • Dunn, L. M., and Markwardt, F. C. (1970).Examiner's Manual: Peabody Individual Achievement Test, American Guidance Service, Circle Pines, MN.

    Google Scholar 

  • Eaves, L. J., Last, K., Young, P., and Martin, N. G. (1978). Model-fitting approaches to the analysis of human behaviour.Heredity 41:249–320.

    Google Scholar 

  • Finucci, J. M., and Childs, B. (1981). Are there really more dyslexis boys than girls? In A. Ansara, N. Geschwind, A. M. Galaburda, M. Albert, and N. Gartrell (eds.).Sex Differences in Dyslexia, Orton Dyslexia Society, Towson, MD, pp. 1–10.

    Google Scholar 

  • Fulker, D. W., Cardon, L. R., DeFries, J. C., Kimberling, W. J., Pennington, B. F., and Smith, S. D. (1991). Multiple regression analysis of sib-pair data on reading to detect quantitative trait loci.Read. Writing Interdisc J. 3:299–331.

    Google Scholar 

  • Geschwind, N. (1981). A reaction to the conference on sex differences and dyslexia. In A. Ansara, N. Geschwind, A. M. Galaburda, M. Albert, and N. Gartrell (eds.),Sex Differences in Dyslexia, Orton Dyslexia Society, Towson, MD, pp. xiii-xviii.

    Google Scholar 

  • Geschwind, N., and Behan, P. (1982). Left-handedness: Association with immune disease, migraine, and developmental learning disorder.Proc. Natl. Acad. Sci. 79:5097–5100.

    Google Scholar 

  • Geschwind, N., and Galaburda, A. M. (1985). Cerebral lateralization: Biological mechanisms, associations, and pathology (parts i, ii, and iii).Arch. Neurol. 42:428–654.

    Google Scholar 

  • Gillis, J. J., and DeFries, J. C. (1989). Validity of school history as a diagnostic criterion for reading disability.Read. Writ. Interdisc. J. 2:93–101.

    Google Scholar 

  • James, W. H. (1992). The sex ratios of dyslexic children and their sibs.Dev. Med. Child Neurol. 34:530–533.

    Google Scholar 

  • Lubs, H. A., Rabin, M., Feldman, E., Kushch, A., Gross-Glenn, K., Duara, R., and Elston, R. C. (1993). Familial dyslexia: Genetic and medical findings in eleven three-generation families.Ann. Dyslex. 43:44–60.

    Google Scholar 

  • Martin, N. G., and Wilson, S. R. (1982). Bias in the estimation of heritability from truncated samples of twins.Behav. Genet. 12:467–472.

    Google Scholar 

  • Neale, M. C. (1991).Mx: Statistical Modeling, Department of Human Genetics, Box 3, MCV, Richmond, VA 23298.

    Google Scholar 

  • Neale, M. C., and Cardon, L. R. (1992).Methodology for Genetic Studies of Twins and Families Kluwer Academic, Dordrech, The Netherlands.

    Google Scholar 

  • Neale, M. C., and Martin, N. G. (1989). The effects of age, sex, and genotype on self-report drukenness following a challenge dose of alcohol.Behav. Genet.,19:63–78.

    Google Scholar 

  • Nichols, R. C., and Bilbro, W. C. (1966). The diagnosis of twin zygosity.Acta Genet. Stat. Med. 16:265–275.

    Google Scholar 

  • Petrill, S. A., and Thompson, L. A. (1994). The effect of gender upon heritability and common environmental estimates in measures of scholastic achievement.Personal. Indiv. Diff. 16:631–640.

    Google Scholar 

  • Plomin, R., DeFries, J. C., and McClearn, G. E. (1990).Behavioral Genetics: A Primer. Freeman, New York.

    Google Scholar 

  • Shaywitz, S. E., Shaywitz, B. A., Fletcher, J. M., and Escobar, M. D. (1990). Prevalence of reading disability in boys and girls.JAMA 264:998–1002.

    Google Scholar 

  • Smith, S. D., Pennington, B. F., and Lubs, H. A. (1983). Specific reading disability: Identification of an inherited form through linkage analysis.Science 219:1345–1347.

    Google Scholar 

  • Smith, S. D., Kimberling, W. J., and Pennington, B. F. (1991). Screening for multiple genes influencing dyslexia.Read. Writ. Interdisc. J. 3:285–298.

    Google Scholar 

  • Stevenson, J. (1992). Identifying sex differences in reading disability: Lessons from a twin study.Read. Writ. Interdisc. J. 4:307–326.

    Google Scholar 

  • Symmes, J. S., and Rapoport, J. L. (1972). Unexpected reading failure.Am. J. Orthopsychiat. 42:82–91.

    Google Scholar 

  • Tallal, P., and Fitch R. H. (1993). Hormones and cerebral organization: Implications for the development and transmission of language and learning disabilities. In A. M. Galaburda (ed.),Dyslexia and Development. Neurobiological Aspects of Extra-Ordinary Brains, Harvard University Press, Camrbidge, MA, pp. 168–186.

    Google Scholar 

  • Tallal, P., Ross, R., and Curtiss, S. (1989). Unexpected sexratios in families of language/learning-impaired children.Neuropsychologia 27:987–998.

    Google Scholar 

  • Vogel, S. (1990). Gender differences in intelligence, language, visual-motor abilities, and academic achievement in students with learning disabilities: A review of the literature.J. Learn Disabil. 23:44–52.

    Google Scholar 

  • Wadsworth, S. J., DeFries, J. C., Stevenson, J., Gilger, J. W., and Pennington, B. F. (1992). Gender ratios among reading-disabled children and their siblings as a function of parental impairment.J. Child Psychol. Psychiat. 33:1229–1239.

    Google Scholar 

  • Wechsler, D. (1974).Examiner's Manual: Wechsler Intelligence Scale for Children—Revised, The Psychological Corporation, New York.

    Google Scholar 

  • Wechsler, D. (1981).Examiner's Manual: Wechsler Adult Intelligence Scale—Revised, The Psychological Corporation, New York.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Alarcón, M., DeFries, J.C. & Fulker, D.W. Etiology of individual differences in reading performance: A test of sex limitation. Behav Genet 25, 17–23 (1995). https://doi.org/10.1007/BF02197238

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02197238

Key Words

Navigation