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Antiarthritic and immunosuppressive effects of Pseudomonas aeruginosa

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Abstract

Fractions obtained from Pseudomonas aeruginosa suppressed microcrystal synovitis in pigeons, adjuvant arthritis and experimental allergic encephalomyelitis in rats, the tuberculin reaction in guinea-pigs and the homograft reaction and antibody formation in mice. Products of gram-negative bacteria thus impair nonimmunological inflammatory processes as well as in vivo manifestations of immune-mediated reactions.

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Floersheim, G.L., Borel, J.F., Wiesinger, D. et al. Antiarthritic and immunosuppressive effects of Pseudomonas aeruginosa. Agents and Actions 2, 231–235 (1972). https://doi.org/10.1007/BF02087047

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