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Peripheral concentrations of gonadotrophins and sexual steroids in infertile males

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Abstract

Relationships between the spermiogram and sex hormones in 104 andrologic patients were studied. Endocrine connections in normal and in pathologic spermiogenesis have been studied. A rather close correlation was found between FSH and ICSH levels. ICSH increases parallel with the increase of FSH level. There is also a close relationship between sperm concentration and FSH level. Between ICSH and sperm count the correlation is not significant. Between steroid hormone level and sperm concentration no correlation was found. It is only the plasma FSH level which shows a close relationship with the disorder of spermiogenesis and it has diagnostic significance.

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References

  1. Aiginger, P., Kolbe, H., Kühböck, J., Spona, J.: The function of the pituitary-gonadal axis in patients with testicular cancer.Acta endocr. (Kbh.), Suppl. 225 (1979).

  2. Brenner, P. F., Guerrero, R., Cekam, Z., Diczfalusy, E.: Radioimmunoassay method for sex steroids in human plasma.Steroids, 22, 775 (1973).

    Google Scholar 

  3. Eik-Nes, K. B.: Human chorionic gonadotrophin as stimulator for androgen secretion. The Endocrine Function of the Human Testis. Vol. 2. Academic Press, Inc., New York-London 1974, p. 207.

    Google Scholar 

  4. Franchimont, P., Demoulin, A., Verstaelen-Proyard, J., Haree-Hagelstein, M. T., Walton, J. S., Waites, G. M. H.: Nature and mechanism of action of Inhibin: Perspective in regulation of male fertility.Int. J. Androl., Suppl.2, 69 (1978).

    Google Scholar 

  5. Kastin, A. J., Schally, A. V., Gual, C., Midgley, J. R., Bowers, C. Y., Diaz-Infante, A.: Stimulation of LH release in men and women by LH-releasing hormone purified from procine hypothalami.J. Clin. Endocr., 29, 1046 (1969).

    Google Scholar 

  6. Kretser, D. M.: Endocrinology of male infertility.Brit. Med. Bull., 35, 187 (1979).

    Google Scholar 

  7. Lincoln, G. A.: Pituitary control of testicular activity.Brit. Med. Bull., 35, 167 (1979).

    Google Scholar 

  8. Lipsett, M. B.: Steroid secretion by the testis in man. The Endocrine Function of the Human Testis. Vol. 2. Academic Press, Inc., New York-London 1974.

    Google Scholar 

  9. Lipsett, M. B.: Steroid regulation of gonadotropin secretion. The Endocrine Function of the Human Testis. Academic Press, Inc., New York-London 1974, p. 41.

    Google Scholar 

  10. Lunenfeld, B., Insler, V.: Infertility, Diagnosis and Treatment of Functional Infertility. Grosse Verlag, Berlin 1978.

    Google Scholar 

  11. Means, A. R., Dedman, J. R., Tindall, D. J., Welsh, M. J.: Hormonal regulation of Sertoli cells.Int. J. Androl., Suppl.2, 403 (1978).

    Google Scholar 

  12. Nankin, H. R., Troen, P.: Evaluation of testosterone in the male. In: E. S. E. Hafez (ed.): Techniques of Human Andrology. Elsevier/North-Holland Biomedical Press, Amsterdam 1977.

    Google Scholar 

  13. Payne, A. H., Zipf, W. B.: Leydig cell function by prolactin growth hormone and lutein izing hormone.Int. J. Androl., Suppl.2, 329 (1978).

    Google Scholar 

  14. Pierrepoint, C. G., John, B. M., Groom, G. V., Wilson, D. W., Gow, J. G.: Prolactin and testosterone levels in the plasma of fertile and infertile men.J. Endocr., 76, 171 (1978).

    Google Scholar 

  15. Purvis, K., Brenner, P. F., Landgern, B. M., Cekam, Z., Diczfalusy, E.: Studies of gonadal function on the human male.J. Clin. Endocr., 4, 237 (1975).

    Google Scholar 

  16. Santen, R. J.: Aromatisation of testosterone to estradiol required for inhibition of luteinising hormone secretion in men.J. Clin. Invest., 56, 1555 (1955).

    Google Scholar 

  17. Sas, M., Szöllősi, J., Falkay, Gy., Scultéty, S.: Serum testosterone level in andrological patients.Orv. Hetil., 116, 2939 (1975).

    PubMed  Google Scholar 

  18. Segal, S., Polisnuk, W. Z., Ben David, M.: Hyperprolactinaemic male infertility.Fertil. Steril., 27, 1425 (1976).

    PubMed  Google Scholar 

  19. Steinberger, A., Steinberger, E.: Secretion of FSH-inhibiting factor by cultured Sertoli cells.Endocrinology, 99, 918 (1976).

    PubMed  Google Scholar 

  20. Strott, C. A., Yoshimi, T., Lipsett, M. B.: Plasma progesterone and 17-hydroxyprogesterone in normal man and children with congenital adrenal hyperplasia.J. Clin. Invest., 48, 930 (1969).

    PubMed  Google Scholar 

  21. Thorner, M. O., Besser, G. M.: Hyperprolactinaemia and gonadal function: results of Bromocriptine treatment. In: Crosignani, P. G., Robyn, C. (eds): Prolactin and Human Reproduction. Academic Press, Inc., London 1977.

    Google Scholar 

  22. Tindall, D. J., Cunningham, G. R., Means, A. R.: Structural requirements for steroid binding to androgen binding protein.Int. J. Androl., Suppl.2, 434 (1978).

    Google Scholar 

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Sas, M., Szöllősi, J., Morvay, J. et al. Peripheral concentrations of gonadotrophins and sexual steroids in infertile males. International Urology and Nephrology 13, 279–286 (1981). https://doi.org/10.1007/BF02082426

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  • DOI: https://doi.org/10.1007/BF02082426

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