Skip to main content
Log in

Peritoneal clearances in scleroderma and diabetes mellitus: Effects of intraperitoneal isoproterenol

  • Published:
International Urology and Nephrology Aims and scope Submit manuscript

Abstract

Reduced peritoneal clearances of creatinine and urate were demonstrated repeatedly in a patient with scleroderma and a patient with diabetes mellitus. Urea clearances were not significantly different from usual values. The findings suggest decreased peritoneal membrane permeability and/or area (if urea clearance is flow limited). Clearances increased to usual values with intraperitoneal isoproterenol in the patient with diabetes. There was no effect of isoproterenol in the patient with scleroderma.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Brown, S. T., Ahearn, D. J., Nolph, K. D.: Reduced peritoneal clearances in scleroderma increased by intraperitoneal isoproterenol.Ann. Int. Med. 78, 891 (1973).

    PubMed  Google Scholar 

  2. Henderson, L. W., Nolph, K. D.: Altered permeability of the peritoneal membrane after using hypertonic peritoneal dialysis fluid.J. Clin. Invest. 48, 992 (1969).

    PubMed  Google Scholar 

  3. Henry, R. J., Chiamori, N.: On the direct Nesslerization of ammonia formed by urease treatment of blood serum, and urine.Am. J. Clin. Pathol. 29, 277 (1958).

    PubMed  Google Scholar 

  4. Henry, R. J., Sobel, C., Kim, J.: A modified carbonate-phosphotungstate method for the the determination of uric acid and comparison with the spectrophotometric uricase method.Am. J. Clin. Pathol. 28, 152 (1957).

    PubMed  Google Scholar 

  5. Karnovsky, M. J.: The ultrastructural basis of capillary permeability studied with peroxidase as a tracer.J. Cell Biol. 35, 213 (1967).

    PubMed  Google Scholar 

  6. Nolph, K. D., Stolz, M. L., Maher, J. F.: Altered peritoneal permeability in patients with systemic vasculitis.Ann. Int. Med. 75, 753 (1971).

    PubMed  Google Scholar 

  7. Nolph, K. D., Whitcomb, M. E., Schrier, R. W.: Mechanisms for inefficient peritoneal dialysis in acute renal failure associated with heat stress and exercise.Ann. Int. Med. 71, 317 (1969).

    PubMed  Google Scholar 

  8. Owen, J. A., Iggo, B., Scandrett, F. J., Stewart, C. P.: The determination of creatinine in plasma or serum, and in urine; a critical examination.Biochem. J. 58, 426 (1954).

    PubMed  Google Scholar 

  9. Romeo, S. G., Whalen, R. E., Tindall, J. P.: Intra-arterial administration of reserpine.Arch. Int. Med. 125, 825 (1970).

    Google Scholar 

  10. Willerson, J. T., Thompson, R. H., Hookman, P., Herdt, J., Decker, J. L.: Reserpine in Raynaud's disease and phenomenon. Short-term response to intra-arterial injection.Ann. Int. Med. 72, 17 (1970).

    PubMed  Google Scholar 

  11. Winkelmann, R. K., Kierland, R. R., Perry, H. O., Muller, S. A., Sams, W. M. Jr.: Management of scleroderma.Mayo Clin. Proc. 46, 128 (1971).

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Nolph, K.D., Miller, L., B. S. et al. Peritoneal clearances in scleroderma and diabetes mellitus: Effects of intraperitoneal isoproterenol. International Urology and Nephrology 8, 161–169 (1976). https://doi.org/10.1007/BF02082213

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02082213

Keywords

Navigation