Summary
After section of the hypothalamic-hypophyseal neurosecretory pathway of the toad accumulation of neurosecretory material both proximally and distally to the plane of section was observed. When, in other animals, a second section close to the neurohypophysis was performed, neurosecretory material was absent in the distal stump resulting from the first section. The pile-up of neurosecretion in the distal stump of the unisectioned tract is attributable to a backward flow from the neurohypophysis to the lesion rather than to local synthesis of neurosecretion.
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References
Christ, J. F: The early changes in the hypophysial neurosecretory fibres after coagulation. In: Neurosecretion, p. 125–147 (eds.H. Heller andR. B. Clark). New York: Academic Press 1962.
Etkin, W.: Neurosecretory control of the pars intermedia. Gen. comp. Endocr.2, 161–169 (1962).
Gerschenfeld, H. M., J. H. Tramezzani, andE. de Robertis: Ultrastructure and function in the neurohypophysis of the toad. Endocrinology66, 741–762 (1960).
Giusti, L., yB. A. Houssay: Alteraciones cutáneas y genitales en el sapo por lesiones de la hipófisis y del cerebro. Rev. Soc. argent. Biol.5, 173–177 (1924).
Green, J. D., andD. S. Maxwell: Comparative anatomy of the hypophysis and observations on the mechanism of neurosecretion. In: Comparative Endocrinology, p. 125–147 (ed.A. Gorbman). New York: John Wiley & Sons 1962.
Mellinger, J.: Étude histophysiologique du système hypothalamo-hypophysaire deScyliorhinus caniculus (L.) en état de mélanodispersion permanente. Gen. comp. Endocr.3, 26–45 (1963).
Ochs, S.: Axoplasmic flow in neurons. In: Macromolecules and behavior, p. 20–39 (ed.J. Gaito). Toronto: Meredith Publ. Co. 1966.
Wilson, L. D., J. A. Weinberg, andH. A. Bern: The hypothalamic neurosecretory system in the tree frog “Hyla regilla”. J. comp. Neurol.107, 253–271 (1957).
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Iturriza, F.C., Restelli, M.A. Neurosecretion in the distal stump of the sectioned hypothalamic-hypophyseal tract in the toad. Z.Zellforsch 81, 297–302 (1967). https://doi.org/10.1007/BF02075975
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DOI: https://doi.org/10.1007/BF02075975