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Neurosecretion in the distal stump of the sectioned hypothalamic-hypophyseal tract in the toad

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Summary

After section of the hypothalamic-hypophyseal neurosecretory pathway of the toad accumulation of neurosecretory material both proximally and distally to the plane of section was observed. When, in other animals, a second section close to the neurohypophysis was performed, neurosecretory material was absent in the distal stump resulting from the first section. The pile-up of neurosecretion in the distal stump of the unisectioned tract is attributable to a backward flow from the neurohypophysis to the lesion rather than to local synthesis of neurosecretion.

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Iturriza, F.C., Restelli, M.A. Neurosecretion in the distal stump of the sectioned hypothalamic-hypophyseal tract in the toad. Z.Zellforsch 81, 297–302 (1967). https://doi.org/10.1007/BF02075975

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  • DOI: https://doi.org/10.1007/BF02075975

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