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Preparation conditions and swelling equilibria of biodegradable hydrogels prepared from microbial poly(γ-glutamic acid) and poly(ε-lysine)

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Abstract

Biodegradable hydrogels prepared by γ-irradiation from microbial poly(amino acid)s are reviewed. pH-sensitive hydrogels were prepared by means of γ-irradiation of poly(γ-glutamic acid) (PGA) produced byBacillus subtilis IFO3335 and poly(ε-lysine) (PL) produced byStreptomyces albulus in aqueous solutions. The preparation conditions, swelling equilibria, hydrolytic degradation, and enzymatic degradation of these hydrogels were studied. A hydrogel with a wide variety of swelling behaviors has been produced by γ-irradiation from a mixture solution of PGA and PL.

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References

  1. M. Kunioka (1993)Kobunshi Ronbunshu 50, 755–760 (in Japanese).

    Google Scholar 

  2. H. J. Choi and M. Kunioka (1995)Radiat. Phys. Chem. 46, 175–179.

    Google Scholar 

  3. M. Kunioka and H. J. Choi (1995)J. Appl. Polym. Sci. 58, 801–806.

    Google Scholar 

  4. M. Kunioka (1995)Sen-i Gakkaisi 51, 137–142 (in Japanese).

    Google Scholar 

  5. S. Murao (1969)Kobunshi 16, 1204–1212 (in Japanese).

    Google Scholar 

  6. F. A. Troy (1973)J. Biol. Chem. 248, 305–315.

    PubMed  Google Scholar 

  7. C. Cheng, Y. Asada, and T. Aida (1989)Agr. Biol. Chem. 53, 2369–2375.

    Google Scholar 

  8. H. Kubota, T. Matsunobu, K. Uotani, H. Takebe, A. Satoh, T. Tanaka, and M. Taniguchi (1993)Biosci. Biotech. Biochem. 57, 1212–1213.

    Google Scholar 

  9. M. Kunioka and A. Goto (1994)Appl. Microbiol. Biotechnol. 40, 867–872.

    Google Scholar 

  10. G. A. Birrer, A.-M. Cromwick, and R. A. Gross (1994)Int. J. Biol. Macromol. 16, 265–275.

    PubMed  Google Scholar 

  11. G. Ivánovics and L. Erdös (1937)Z. Immunitätsforsch 90, 5–19.

    Google Scholar 

  12. G. Ivánovics and V. Bruckner (1937)Z. Immunitätsforsch 90, 304–318.

    Google Scholar 

  13. M. Bovarnick (1942)J. Biol. Chem. 145, 415–424.

    Google Scholar 

  14. S. Sawamura (1905)J. Coll. Agr. Tokyo 5, 189–191.

    Google Scholar 

  15. H. Fujii (1963)Nippon Nogeikagaku Kaishi 37, 407–411 (in Japanese).

    Google Scholar 

  16. T. Hara and S. Ueda (1982)Agr. Biol. Chem. 46, 2275–2281.

    Google Scholar 

  17. T. Hara, A. Aumayr, Y. Fujio, and S. Ueda (1982)Appl. Environ. Microbiol. 44, 1456–1458.

    PubMed  Google Scholar 

  18. T. Tanaka, O. Hiruta, T. Futamura, K. Uotani, A. Satoh, M. Taniguchi, and S. Oi (1993)Biosci. Biotech. Biochem. 57, 2148–2153.

    Google Scholar 

  19. S. Shima and H. Sakai (1977)Agr. Biol. Chem. 41, 1807–1809.

    Google Scholar 

  20. S. Shima and H. Sakai (1981)Agr. Biol. Chem. 45, 2497–2502.

    Google Scholar 

  21. S. Shima, S. Ohshima, and H. Sakai (1983)Nippon Nogeikagaku Kaishi 57, 221–226 (in Japanese).

    Google Scholar 

  22. S. Shima, H. Matsuoka, T. Iwamoto, and H. Sakai (1984)J. Antibiot. 37, 1449–1455.

    PubMed  Google Scholar 

  23. H. Kubota, Y. Nambu, and T. Endo (1993)J. Polym. Sci. A Polym. Chem. 31, 2877–2879.

    Google Scholar 

  24. S. A. Giannos, D. Shah, R. A. Gross, D. L. Kaplan, and J. M. Mayer (1990)ACS Polym. Prep. 31, 209–210.

    Google Scholar 

  25. K. Yahata, J. Sadanobu, and T. Endo (1992)Polym. Prepr. Japan 41, 1077 (in Japanese).

    Google Scholar 

  26. M. Inagaki, N. Tubokawa, and T. Endo (1991)Polym. Prepr. Japan 40, 411 (in Japanese).

    Google Scholar 

  27. K. Kakinoki, A. Kishida, M. Akashi, and T. Endo (1993)Chem. Soc. Japan Prepr. 65II, 258 (in Japanese).

    Google Scholar 

  28. A. Amamiya (1962)Houshasenn Kagaku Nyuumon, Vol. 2, Maruzen, Tokyo, pp. 474, 544.

    Google Scholar 

  29. T. Nagai, Y. Yamamoto, and H. Takeuchi (1973) Japanese patent, 48-85687.

  30. A. Goto and M. Kunioka (1992)Biosci. Biotech. Biochem. 56, 1031–1035.

    Google Scholar 

  31. H. J. Choi, R. Yang, and M. Kunioka (1995)J. Appl. Polym. Sci. 58, 807–814.

    Google Scholar 

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Authors and Affiliations

  1. National Institute of Materials and Chemical Research, 1-1 Higashi, Tsukuba-shi, 305, Ibaraki, Japan

    Masao Kunioka

  2. Doosan Technical Center, 39-3 Songbok-ri, Suji-myon, Yongin-gun, 449-840, Kyonggi-do, Korea

    Hyuk Joon Choi

Authors
  1. Masao Kunioka
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  2. Hyuk Joon Choi
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Kunioka, M., Choi, H.J. Preparation conditions and swelling equilibria of biodegradable hydrogels prepared from microbial poly(γ-glutamic acid) and poly(ε-lysine). J Environ Polym Degr 4, 123–129 (1996). https://doi.org/10.1007/BF02074873

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  • DOI: https://doi.org/10.1007/BF02074873

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