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The blood flow in the forearm in patients with cardiac failure

II. The relationship between the blood flow and oxygen consumption in the muscle of the forearm in patients with low cardiac output

  • Published:
Zeitschrift für Die Gesamte Experimentelle Medizin einschließlich experimentelle Chirurgie

Summary

The relationship between the blood flow and oxygen consumption in the muscle in patients with cardiac failure, and the influence of the elevation of the forearm on its blood flow and the clearance of131J have been studied.

The decrease of blood flow in the muscle in patients with heart failure was not accompanied with a significant decrease of the oxygen consumption in the muscle. During the elevation of the forearm in healthy subjects and in patients, in whom the blood flow was higher than 2.5 ml/ 100 ml tissue/min, a significantly higher decrease of blood flow was observed than in patients in whom the blood flow of the forearm was less than 2.5 ml/100 ml tissue/min. The elevation of the forearm did not significantly influence the clearance of131J from the muscle, neither in the control group nor in patients with cardiac failure.

Zusammenfassung

Wir untersuchten die Beziehung zwischen der Durchblutung und dem Sauerstoffverbrauch des Unterarmes bei kardial dekompensierten Patienten sowie den Einfluß einer Elevation des Unterarmes auf den Blutdurchfluß und auf die131J-Clearance aus der Muskulatur.

Eine Verminderung des Blutdurchflusses des Unterarmes bei kardial dekompensierten Patienten war nicht mit einer sichtbaren Senkung des Sauerstoffverbrauches verbunden. Während der Elevation des Unterarmes bei kardial gesunden Personen sowie bei Patienten mit größerem Blutdurchfluß des Unterarmes als 2,5 ml/100 ml Gewebe/min war die Verminderung desselben sichtbar größer als bei Patienten, bei denen der Blutdurchfluß geringer als 2,5 ml/100 ml Gewebe/min war. Die Elevation des Unterarmes beeinflußte die131J-Clearance aus der Muskulatur nicht sichtbar, weder in der Kontrollgruppe noch bei kardial dekompensierten Patienten.

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References

  1. Barcroft, H., W. McK. Bonnar, O. G. Edholm, andA. S. Eferon: On sympathetic vasoconstrictor tone in human skeletal muscle. J. Physiol. (Lond.)102, 21 (1943).

    CAS  Google Scholar 

  2. —, andA. H. Kitchin: Are there arteriovenous anastomoses in the human forearm. Symposium sur les interactions artério-veineuses. Angiology9, 24 (1957).

    CAS  Google Scholar 

  3. Barlow, T. E., A. L.Haigh, and D. N.Walder: A search for arteriovenous anastomoses in skeletal muscle. J. Physiol. (Lond.)143, 80P (1958).

    Google Scholar 

  4. — — —: Evidence for two vascular pathways in skeletal muscle. Clin. Sci.20, 367 (1961).

    PubMed  CAS  Google Scholar 

  5. Brod, J., Z. Hejl, andM. Ulrych: Metabolic changes in the forearm muscle and skin during emotional muscular vasodilatation. Clin. Sci.25, 1 (1963).

    PubMed  CAS  Google Scholar 

  6. Holling, H. E., andD. Verel: Circulation in the elevated forearm. Clin. Sci.16, 197 (1957).

    PubMed  CAS  Google Scholar 

  7. Hyman, C.: Physiological implications of a dual circulation in muscle. Symposium sur les interactions artério-veineuses. Angiology9, 25 (1957).

    CAS  Google Scholar 

  8. —,S. Rosell, A. Rosén, R. R. Sonnenschein, andB. Uvnäs: Effects of alterations of total muscular blood flow on local tissue clearance of radioiodide in the cat. Acta physiol. scand.46, 358 (1959).

    PubMed  CAS  Google Scholar 

  9. Kety, S. S.: Measurement of regional circulation by local clearance of radioactive sodium. Amer. Heart J.28, 321 (1949).

    Article  Google Scholar 

  10. Mottram, R. F.: The oxygen consumption of human skeletal muscle in vivo. J. Physiol. (Lond.)128, 268 (1955).

    CAS  Google Scholar 

  11. Renkin, E. M., andS. Rosell: Effects of different types of vasodilatator mechanisms on vascular tonus and on transcapillary exchange of diffusible material in skeletal muscle. Acta physiol. scand.54, 241 (1962).

    Article  PubMed  CAS  Google Scholar 

  12. Schroeder, W.: Nutritive und nicht-nutritive Skelettmuskeldurchblutung. Arch. Kreisl.-Forsch.49, 36 (1966).

    Article  CAS  Google Scholar 

  13. Schweitzer, P., M. Pivoňka, andH. Klvańová: The blood flow in the forearm in patients with cardiac failure, I. The relationship between the cardiac output and the blood flow in the forearm. Z. ges. exp. Med.143, 126 (1967).

    Article  CAS  Google Scholar 

  14. —, andM. Torma: Oxygen consumption and blood flow in the muscle of the forearm in patients with cardiac failure. Clin. Sci.25, 493 (1963).

    PubMed  CAS  Google Scholar 

  15. Zweifach, B. W., andD. B. Metz: Selective distribution of blood through the terminal vascular bed of mesenteric structure and skeletal muscle. Angiology6, 282 (1955).

    PubMed  CAS  Google Scholar 

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Schweitzer, P., Pivoňka, M. & Klvaňová, H. The blood flow in the forearm in patients with cardiac failure. Z. Gesamte Exp. Med. 143, 136–142 (1967). https://doi.org/10.1007/BF02042881

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  • DOI: https://doi.org/10.1007/BF02042881

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