Summary
The relationship between the blood flow and oxygen consumption in the muscle in patients with cardiac failure, and the influence of the elevation of the forearm on its blood flow and the clearance of131J have been studied.
The decrease of blood flow in the muscle in patients with heart failure was not accompanied with a significant decrease of the oxygen consumption in the muscle. During the elevation of the forearm in healthy subjects and in patients, in whom the blood flow was higher than 2.5 ml/ 100 ml tissue/min, a significantly higher decrease of blood flow was observed than in patients in whom the blood flow of the forearm was less than 2.5 ml/100 ml tissue/min. The elevation of the forearm did not significantly influence the clearance of131J from the muscle, neither in the control group nor in patients with cardiac failure.
Zusammenfassung
Wir untersuchten die Beziehung zwischen der Durchblutung und dem Sauerstoffverbrauch des Unterarmes bei kardial dekompensierten Patienten sowie den Einfluß einer Elevation des Unterarmes auf den Blutdurchfluß und auf die131J-Clearance aus der Muskulatur.
Eine Verminderung des Blutdurchflusses des Unterarmes bei kardial dekompensierten Patienten war nicht mit einer sichtbaren Senkung des Sauerstoffverbrauches verbunden. Während der Elevation des Unterarmes bei kardial gesunden Personen sowie bei Patienten mit größerem Blutdurchfluß des Unterarmes als 2,5 ml/100 ml Gewebe/min war die Verminderung desselben sichtbar größer als bei Patienten, bei denen der Blutdurchfluß geringer als 2,5 ml/100 ml Gewebe/min war. Die Elevation des Unterarmes beeinflußte die131J-Clearance aus der Muskulatur nicht sichtbar, weder in der Kontrollgruppe noch bei kardial dekompensierten Patienten.
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References
Barcroft, H., W. McK. Bonnar, O. G. Edholm, andA. S. Eferon: On sympathetic vasoconstrictor tone in human skeletal muscle. J. Physiol. (Lond.)102, 21 (1943).
—, andA. H. Kitchin: Are there arteriovenous anastomoses in the human forearm. Symposium sur les interactions artério-veineuses. Angiology9, 24 (1957).
Barlow, T. E., A. L.Haigh, and D. N.Walder: A search for arteriovenous anastomoses in skeletal muscle. J. Physiol. (Lond.)143, 80P (1958).
— — —: Evidence for two vascular pathways in skeletal muscle. Clin. Sci.20, 367 (1961).
Brod, J., Z. Hejl, andM. Ulrych: Metabolic changes in the forearm muscle and skin during emotional muscular vasodilatation. Clin. Sci.25, 1 (1963).
Holling, H. E., andD. Verel: Circulation in the elevated forearm. Clin. Sci.16, 197 (1957).
Hyman, C.: Physiological implications of a dual circulation in muscle. Symposium sur les interactions artério-veineuses. Angiology9, 25 (1957).
—,S. Rosell, A. Rosén, R. R. Sonnenschein, andB. Uvnäs: Effects of alterations of total muscular blood flow on local tissue clearance of radioiodide in the cat. Acta physiol. scand.46, 358 (1959).
Kety, S. S.: Measurement of regional circulation by local clearance of radioactive sodium. Amer. Heart J.28, 321 (1949).
Mottram, R. F.: The oxygen consumption of human skeletal muscle in vivo. J. Physiol. (Lond.)128, 268 (1955).
Renkin, E. M., andS. Rosell: Effects of different types of vasodilatator mechanisms on vascular tonus and on transcapillary exchange of diffusible material in skeletal muscle. Acta physiol. scand.54, 241 (1962).
Schroeder, W.: Nutritive und nicht-nutritive Skelettmuskeldurchblutung. Arch. Kreisl.-Forsch.49, 36 (1966).
Schweitzer, P., M. Pivoňka, andH. Klvańová: The blood flow in the forearm in patients with cardiac failure, I. The relationship between the cardiac output and the blood flow in the forearm. Z. ges. exp. Med.143, 126 (1967).
—, andM. Torma: Oxygen consumption and blood flow in the muscle of the forearm in patients with cardiac failure. Clin. Sci.25, 493 (1963).
Zweifach, B. W., andD. B. Metz: Selective distribution of blood through the terminal vascular bed of mesenteric structure and skeletal muscle. Angiology6, 282 (1955).
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Schweitzer, P., Pivoňka, M. & Klvaňová, H. The blood flow in the forearm in patients with cardiac failure. Z. Gesamte Exp. Med. 143, 136–142 (1967). https://doi.org/10.1007/BF02042881
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DOI: https://doi.org/10.1007/BF02042881