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Cadmium and zinc determination by neutron activation analysis and biochemical tests in tissues of workers professionally exposed to cadmium

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Abstract

Cadmium and zinc levels in urine, serum, hair obtained from workers professionally exposed to cadmium oxide dust and from a control, nonoccupationally exposed group were determined by neutron activation analysis. The study was completed by biochemical monitoring tests such as the β22-MG) determination in urine and serum and the δ-aminolevulinic acid dehydratase (ALAD) determination in blood. Significantly increased levels of cadmium in urine, serum, and hair, β2-MG in urine and serum, ALAD in blood and decreased levels of zinc in serum were found in the exposed group compared to the control group. The most distinct differences of the parameters studied were observed for cadmium in hair. Correlations among the parameters were preliminary evaluated, too. For quality assurance purposes, the cadmium and zinc concentrations were determined in biological (standard) reference materials NBS SRM-1577 Bovine Liver, Bowen's Kale, IAEA A-11 Milk Powder, and IAEA H-8 Horse Kidney.

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References

  1. H. A. ROELS, R. R. LAUWERYS, J. P. BUCHET, A. BERNARD, Environ. Res., 24 (1981) 117.

    PubMed  Google Scholar 

  2. R. R. LAUWERYS, J. P. BUCHET, H. A. ROELS, J. BROWERS, D. STANESCU, Arch. Environ. Health, 28 (1974) 145.

    PubMed  Google Scholar 

  3. K. TSUCHIYA (Ed.), Cadmium Studies in Japan: A Review, Elsevier-North-Holland, Amsterdam, 1978.

    Google Scholar 

  4. K. NOMIYAMA, Sci. Total. Environ., 14 (1980) 199.

    PubMed  Google Scholar 

  5. E. C. FOULKES, Handbook of Environmental Pharmacology, Vol. 80, Springer Verlag, Berlin-Heidelberg, 1986.

    Google Scholar 

  6. R. R. LAUWERYS, A. M. BERNARD, Brit. J. Industr. Med., 43 (1986) 433.

    PubMed  Google Scholar 

  7. M. WEBB (Ed.), The Chemistry, Biochemistry and Biology of Cadmium, Biomedical Press, Elsevier-North-Holland, Amsterdam, 1979.

    Google Scholar 

  8. L. FRIBERG, T. KJELLSTRÖM, G. NORDBERG, M. PISCATOR, Handbook of the Toxicology of Metals, Elsevier-North-Holland, Amsterdam, 1979.

    Google Scholar 

  9. C. G. ELINDER, T. KJELLSTRÖM, C. HOGSTEDT, K. ANDERSSON, G. SPANG, Brit. J. Industr. Med., 42 (1985) 654.

    Google Scholar 

  10. S. KAGAMIMORI, Y. NARUSE, T. FUJITA, M. WATANABE, H. NISHINO, T. SHINMURA, Bull. Environ. Contam. Toxicol., 35 (1985) 386.

    PubMed  Google Scholar 

  11. K. J. ELLIS, K. YUEN, S. YAUSUMURA, S. H. COHEN, Environ. Res., 33 (1984) 216.

    PubMed  Google Scholar 

  12. P. PLEBAN, Science, 208 (1980) 520.

    PubMed  Google Scholar 

  13. V. SENFT, F. H⫲ZL, J. SÝKORA, Prac. Lék., 38 (1986) 99.

    Google Scholar 

  14. V. SENFT, F. H⫲ZL, J. SÝKORA, Prac. Lék., 38 (1986) 134.

    Google Scholar 

  15. Ju. S. RJABUCHIN, Report IAEA/RL/50, IAEA, Vienna, 1978.

  16. Certificate of Analysis for Standard Reference Material 1577, Bovine Liver, NBS, Washington, D. C, Revision 14, June 1977.

  17. IUPAC, Reference Material for Trace Analysis by Radioanalytical Methods: Bowen's Kale, Pure Appl. Chem., 51 (1979) 1183.

    Google Scholar 

  18. R. DYBCZYNSKI, A. VEGLIA, O. SUSCHNY, Report on Intercomparison Run A-11, IAEA/RL/68, IAEA Vienna, July 1980.

    Google Scholar 

  19. A. R. BYRNE, C. CAMARA-RICA, R. CORNELIS, J. J. M. de GOEIJ, G. V. IYENGAR, G. KIRKBRIGHT, G. KNAPP, R. M. PARR, M. STOEPPLER, Fresen. Z. Anal. Chem., 326 (1987) 723.

    Google Scholar 

  20. R. M. PARR, Provisional Certificate of Analysis, IAEA Horse Kidney H-8, IAEA Vienna, 1985.

    Google Scholar 

  21. J. KUČERA, M. CIKRT, M. TICHÝ, P. LEPSI, L. SOUKAL, Rádioakt. Živ. Prostr., 8 (1985) 283.

    Google Scholar 

  22. P. EVRIN, P. A. PETERSON, L. VIDE, I. BERGARRD, Scand. J. Clin. Lab. Invest., 28 (1971) 439.

    PubMed  Google Scholar 

  23. D. BONSIGNORE, P. CALISSANO, S. CARTASEGNA, Med. di Lavoro, 56 (1965) 199.

    Google Scholar 

  24. T. VOTRUBA, L. ROZPRIMOVÁ, K. REITSPIESOVÁ, P. RÁKOSNIK, J. VANČUŘÍK, Čs. Epidem. Microbiol. Imunol., 35 (1986) 24.

    Google Scholar 

  25. L. SACHS, Applied Statistics, A Handbook of Techniques, Springer Verlag, New York-Heidelberg-Berlin, 1982.

    Google Scholar 

  26. S. S. SHAPIRO, M. B. WILK, Biometrika, 52 (1965) 591.

    Google Scholar 

  27. A. E. AMES, G. SZONYI, in B. KOWALSKI (Ed.), Chemometrics: Theory and Applications, ACS Symposium Series 52, Washington D. C., 1977.

  28. A. BERNARD, A. GORET, J. P. BUCHET, H. A. ROELS, R. R. LAUWERYS, J. Toxicol. Environ. Health, 6 (1980) 157.

    Google Scholar 

  29. F. H⫲ZL, J. JANECH, J. SÝKORA, P. NAXERA, P. JANDOVÁ, Prac. Lék. 32 (1980) 181.

    Google Scholar 

  30. V. SENFT, F. H⫲ZL, J. SÝKORA, Prac. Lék., 38 (1986) 453.

    Google Scholar 

  31. G. V. IYENGAR, Report KFA Jül-1974, February 1985.

  32. R. R. LAUWERYS, H. A. ROELS, M. REGNIERS, J. P. BUCHET, A. BERNARD, A. GOREL, Environ. Health, 20 (1979) 376.

    Google Scholar 

  33. J. R. DAVIS, M. J. AVRAM, Toxicol. Appl. Pharmacol., 44 (1978) 181.

    PubMed  Google Scholar 

  34. J. R. DAVIS, M. J. AVRAM, Biol. Appl. Pharmacol., 55 (1980) 281.

    Google Scholar 

  35. E. L. WILSON, P. E. BURGER, E. B. DOWDLE, Eur. J. Biochem., 29 (1972) 563.

    PubMed  Google Scholar 

  36. R. E. JERVIS, G. J. EVANS, P. J. HEWITT, Nutrit. Res., Suppl. I, Pergamon Press Ltd., 1985, p. 627.

  37. G. J. EVANS, R. E. JERVIS, J. Radioanal. Nucl. Chem., 110 (1987) 613.

    Google Scholar 

  38. J. KUČERA, V. SENFT, unpublished results.

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Kučera, J., Senft, V., H⫲zl, F. et al. Cadmium and zinc determination by neutron activation analysis and biochemical tests in tissues of workers professionally exposed to cadmium. Journal of Radioanalytical and Nuclear Chemistry, Articles 122, 361–372 (1988). https://doi.org/10.1007/BF02037784

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