Abstract
Ceil wall deficient forms of bacteria were isolated from 40–60% of patients with active inflammatory bowel disease, 15–25% of patients with inactive disease and only 5–7% of controls. The recovery rate from Crohn's disease and ulcerative colitis tissue filtrates did not differ significantly, but was raised in both groups in comparison with controls (p < 0.01). It is concluded that a range of such bacteria have a possible aetiological role in inflammatory bowel disease.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Belsheim, M. R., Darwish, R. Z., Watson, W. C., Schieven, B.: Bacterial L-form isolation from inflammatory bowel disease patients. Gastroenterology 1983, 85: 364–369.
Ibbotson, J.: Aetiological aspects of inflammatory bowel disease and related disorders. Thesis, University of Birmingham, 1986.
Orr, M. M.: Experimental intestinal granulomas. Proceedings of the Royal Society of Medicine 1975, 68: 34.
Judge, M.S., Mattman, L.H.: Cell-wall deficient bacteria in tuberculosis, sarcoidosis and leprosy. In: Domingue, G.J. (ed.): Cell-wall deficient bacteria: basic principles and clinical significance. Addison-Wesley, 1982, p. 257–298.
Müller, B., Fervers, F., Rohbeck, R., Strohmeyer, G.: Zuckerkonsum bei Patienten mit Morbus Crohn. Verhandlungen der Deutschen Gesellschaft für Innere Medizin 1976, 82: 922–924.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Ibbotson, J.P., Pease, P.E. & Allan, R.N. Cell-wall deficient bacteria in inflammatory bowel disease. Eur. J, Clin. Microbiol. 6, 429–431 (1987). https://doi.org/10.1007/BF02013105
Issue Date:
DOI: https://doi.org/10.1007/BF02013105