Abstract
Magnetic resonance images of optic nerves were obtained in 20 patients with acute optic neuritis (ON), and assessed by means of clinical, visual field and visual evoked potential evaluations; the imaging was repeated 1 year later. The results of the conventional Short Tau Inversion Recovery (STIR) sequence obtained using short time echo (STE-STIR: 22 msec) were compared with those of the long time echo sequence (LTE-STIR: 80 msec). The conventional STE-STIR sequence revealed lesions in 57.2% cases of acute ON and in 42.9% of the optic nerves affected by previous ON: the LTE-STIR sequence was diagnostic in 95.2% of acute ON cases and in 85% of patients with previous ON. The calculated length of the optic nerve lesions was significantly longer in the images obtained using the LTE-STIR sequence than in those obtained using conventional STE-STIR sequences.
Sommario
Si descrivono i risultati ottenuti con indagini di Risonanza Magnetica (RM) dei nervi ottici (eseguite all'esordio e 12 mesi dopo) in 20 pazienti affetti da Neurite Ottica (NO) acuta, valutata in funzione della sintomatologia clinica e delle alterazioni campimetriche e del potenziale evocato visivo.
Sono state analizzate le immagini RM in Short Tau Inversion Recovery (STIR) mettendo a confronto i rilievi ottenuti con sequenza Short Time Echo (STE-STIR: 22 msec) rispetto a quelli ottenuti con Long Time Echo (LTE-STIR: 20 msec). Mentre con la convenzionale STE-STIR è stato possibile rilevare lesioni a carico dei nervi ottici nel 57.2% delle Neuriti Acute e nel 42.9% delle Neuriti Pregresse, la metodica LTE-STIR è risultata diagnostica nel 95.2% delle Neuriti Acute e nel 85% delle Neuriti Pregresse.
Sia nelle NO acute che nelle pregresse, la lunghezza delle lesioni a carico dei nervi ottici sono risultate significativamente maggiori rispetto a quelle ottenute con la convenzionale metodica STE-STIR.
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References
Atlas S.W., Grossman R.I. et al.:STIR-MR imaging of the orbit. Am. J. Neuroradiology 9: 969–974, 1988.
Daniels D.L., Kneeland J.B. et al.:MR imaging of the optic nerve and sheath: correcting the chemical shift misregistration effect. Am. J. Neroradiology 7: 249–253, 1986.
Finn J.P., Kendal B.E. et al.:Myelination, structural abnormalities and disease of white matter an assessment using high field MRI. Neuroradiology 33: 254–256, 1991.
Fulgente T., Thomas A., Lobefalo L., Mastropasqua L., Gallenga P.E., Gambi D., Onofrj M.:Are VEP abnormalities in optic neuritis (ON) dependent on plaque size? A reappraisal of the physiopathology of ON based on improved MRI and multiple lead recordings. Ital. J. Neurol. Sci 17: 43–54, 1996.
Glantz S.A.:Statistica per discipline biomediche. McGraw-Hill Libri Italia s.r.l., 2a edizione, 1988.
Guy J., Mao J., Bidgood J.R., Mancuso A., Quisling R.G.:Enhancement and demyelination of the intraorbital optic nerve. Fat suppression Magnetic resonance Imaging. Ophthalmol. 99: 713–719, 1992.
Hendrick R.E., Roff U.:Image contrast and noise. Stark D.D., Bredley W.G. Jr. Magnetic Resonance Imaging IInd ed., Vol. 1, Mosbey Year Book St. Louis, 109–144, 1992.
Johnson G., Miller D.H., MacManus D. et al.:STIR sequences in NMR imaging of the optic nerve. Neuroradiology 29: 238–245, 1987.
Larsson H.B.W., Thomesen C., Frederiksen J., Henriksen O., Olesen J.:Chemical shift selective magnetic resonance imaging of the optic nerve in patients with acute optic neuritis. Acta Radiol. 29: 629–632, 1988.
Mc Alpine D.:The benign form of Multiple Sclerosis. A study based on 241 cases seen within three years of onset and followed up until the tenth year or more of disease. Brain 84: 86–203, 1961.
Miller D.H., Newton M.R., van der Poel J.C. et al.:Magnetic resonance imaging of the optic nerve in optic neuritis. Neuroradiology 38: 175–179, 1988.
Miller D.H., MacManus D.G., Bortlett P.A., Kapoor R., Morrissey S.P., Moseley I.F.:Detection of optic nerve lesions in optic neuritis using frequency-selective fat- saturation sequences. Neuroradiology 35: 156–158, 1993.
Onofrj M., Bazzano S., Malatesta G., Fulgente T.:Mapped distribution of pattern reversal VEPs to central field and lateral half-field stimuli of different spatial frequencies. Electroenceph. Clin. Neurophysiol. 80: 167–180, 1991.
Onofrj M., Fulgente T., Malatesta G., Ferracci F.:Visual evoked potentials (VEPs) to altitudinal stimuli: effects of stimulus manipulations on VEP scalp topography. Clin. Vision Sci. 8: 529–544, 1993.
Poser C.M., Paty D.W., Scheinberg L. et al.:New diagnostic criteria for Multiple Sclerosis: guidelines for research protocols. Ann. Neurol. 13: 227–231, 1983.
Simon J., Szumowsky J. et al.:Fat-suppression MR imaging of the orbit. Am. J. Neuroradiol. 9: 961–968, 1988.
Youl B.D., Turano G., Miller D.H. et al.:The pathophysiology of acute optic neuritis. An association of Gadolinium leakage with clinical and electrophysiological deficits. Brain 114: 2437–2450, 1991.
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Tartaro, A., Onofrj, M., Delli Pizzi, C. et al. Long time echo STIR sequence magnetic resonance imaging of optic nerves in optic neuritis. Ital J Neuro Sci 17, 35–42 (1996). https://doi.org/10.1007/BF01995707
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DOI: https://doi.org/10.1007/BF01995707