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Effects of scavengers of superoxide radicals, hydrogen peroxide, singlet oxygen and hydroxyl radicals on malondialdehyde generation from arachidonic acid by bovine seminal vesicle microsomes

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Superoxide dismutase, catalase and sodium formate did not inhibit the formation of malondialdehyde (MDA) from arachidonic acid, suggesting that O ∸2 , H2O2 and OH. are not involved in the enzymatical oxidation of arachidonic acid. Sodium azide was found to be an inhibitor of MDA production.

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Authors and Affiliations

  1. Department of Medicinal Chemistry, De Boelelaan 1083, NL-1081 HV, Amsterdam, The Netherlands

    J. de Vries & C. N. Verboom

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  1. J. de Vries
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  2. C. N. Verboom
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de Vries, J., Verboom, C.N. Effects of scavengers of superoxide radicals, hydrogen peroxide, singlet oxygen and hydroxyl radicals on malondialdehyde generation from arachidonic acid by bovine seminal vesicle microsomes. Experientia 36, 1339–1340 (1980). https://doi.org/10.1007/BF01960084

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