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Effect of trifluoperazine and calcium ions on gregarine gliding

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Summary

The drug trifluoperazine (TFP) inhibits the gliding motility of gregarine protozoans. This suggests that the Ca++ binding protein, calmodulin, plays a role in the motility process. However the presence of extracellular Ca++ was not required for gliding to occur.

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Authors and Affiliations

  1. Department of Zoology, University College, Gower Street, WC1 6BT, London, England

    C. A. King & K. Lee

Authors
  1. C. A. King
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  2. K. Lee
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Additional information

Acknowledgments. We should like to thank L. Cooper for technical assistance, Smith, Kline and French for the gift of trifluoperazine, and Terry Preston for valuable discussion.

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King, C.A., Lee, K. Effect of trifluoperazine and calcium ions on gregarine gliding. Experientia 38, 1051–1052 (1982). https://doi.org/10.1007/BF01955361

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  • DOI: https://doi.org/10.1007/BF01955361

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