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The metabolic fate of [35S]-diallyl disulphide in mice

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Summary

Diallyl disulphide (DADS) is a major constituent of garlic oil. Uptake of [35S]-labelled diallyl disulphide by mouse liver is highest at 90 min after treatment. 2h after treatment with [35S]-DADS, 70% of the radioactivity is present in the liver cytosol of which 80% is metabolized to sulphate.

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Pushpendran, C.K., Devasagayam, T.P.A., Chintalwar, G.J. et al. The metabolic fate of [35S]-diallyl disulphide in mice. Experientia 36, 1000–1001 (1980). https://doi.org/10.1007/BF01953845

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