Skip to main content
SpringerLink
Log in

Release of immuno-reactive and biologically active LH from fetal mouse pituitary in response to synthetic gonadotropin releasing factor (LRF)

  • Endocrinologica
  • Published:
Experientia Aims and scope Submit manuscript

Summary

In an incubation system, LRF stimulated significantly the release of LH from 18-day-old mouse fetal pituitary. This LRF-induced LH release, measured by RIA in the incubation medium was able to increase the testosterone production by age-matched fetal testes. This data suggests that the hypothalamo-hypophyseal-testicular axis is functional at the end of mouse prenatal life.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. A. V. Schally andC. Y. Bowers, Endocrinology75, 312 (1964).

    Article  CAS  PubMed  Google Scholar 

  2. V. L. Gay, G. D. Niswender andA. R. Midgley, Jr, Endocrinology86, 1305 (1970).

    Article  CAS  PubMed  Google Scholar 

  3. T. W. Redding, A. V. Schally, A. Arimura andH. Matsuo, Endocrinology90, 764 (1972).

    Article  CAS  PubMed  Google Scholar 

  4. S. J. Schafer andW. H. McShan, Neuroendocrinology16, 332 (1974).

    Article  CAS  PubMed  Google Scholar 

  5. D. L. Foster, T. A. Cruz, G. L. Jackson, B. Cook andA. V. Nalbandov, Endocrinology90, 673 (1972).

    Article  CAS  PubMed  Google Scholar 

  6. G. V. Groom, M. A. Groom, I. D. Cooke andA. R. Boyns, J. Endocr.49, 335 (1971).

    Article  CAS  PubMed  Google Scholar 

  7. C. A. Blake, R. I. Weiner, R. A. Gorski andC. H. Sawyer, Endocrinology90, 855 (1972).

    Article  CAS  PubMed  Google Scholar 

  8. A. Hus-Citharel, unpublished data.

  9. J. A. Mahoudeau andH. Bricaire, Ann. Biol. Clin.30, 559 (1972).

    CAS  Google Scholar 

  10. G. Pointis andJ. A. Mahoudeau, C. r. Acad. Sci., Paris279, 1197 (1974).

    CAS  Google Scholar 

  11. G. Pointis andJ. A. Mahoudeau, Acta endocr., capenh. in press (1976).

  12. P. Franchimont andJ. L. Pasteels, C. r. Acad. Sci., Paris275, 1799 (1972).

    CAS  Google Scholar 

  13. C. Hagen andA. S. McNeilly, J. Endocr.67, 49 (1975).

    Article  CAS  PubMed  Google Scholar 

  14. A. Jost, J. P. Dupouy andM. Rieutort, Recent Progr. Horm. Res.41, 209 (1974).

    CAS  Google Scholar 

Download references

Author information

Author notes

  1. J. A. Mahoudeau

    Present address: Centre de Recherches Endocrinologiques, Hôpital Cochin, 27, rue du Faubourg Saint-Jacques, F-75014, Paris, France

  2. G. Pointis

    Present address: Laboratoire d'Histophysiologie du Collège de France, 4, avenue Gordon-Bennett, 75016, Paris, France

Authors and Affiliations

  1. Laboratoire de Chimie Hormonale, Maternité de Port-Royal, F-75014, Paris, France

    G. Pointis & J. A. Mahoudeau

  2. Centre de Recherches Endocrinologiques, Hôpital Cochin, 27, rue du Faubourg Saint-Jacques, F-75014, Paris, France

    G. Pointis

Authors
  1. G. Pointis
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. A. Mahoudeau
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

The expert technical assistance of MrsM. T. Latreille andA. L'Héritier are grafefully acknowledged.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Pointis, G., Mahoudeau, J.A. Release of immuno-reactive and biologically active LH from fetal mouse pituitary in response to synthetic gonadotropin releasing factor (LRF). Experientia 32, 1347–1348 (1976). https://doi.org/10.1007/BF01953132

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01953132

Keywords

Search

Navigation