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Sylvaticin: A new cytotoxic and insecticidal acetogenin fromRollinia sylvatica (Annonaceae)

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Summary

Sylvaticin (I), a new tetrahydroxy annonaceous acetogenin with nonadjacent tetrahydrofuran rings, has been isolated from the dried fruits ofRollinia sylvatica St. Hil. (Annonaceae). This compound is extremely cytotoxic to human tumor cells and shows promising insect control properties.

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Authors and Affiliations

  1. Northern Regional Research Center, USDA-ARS, 1815 N. University St., 61604, Peoria, Illinois, USA

    K. J. Mikolajczak & R. V. Madrigal

  2. Department of Medicinal Chemistry and Pharmacognosy, School of Pharmacy and Pharmacal Sciences, Purdue University, 47907, West Lafayette, Indiana, USA

    J. K. Rupprecht, Y. -H. Hui, Y. -M. Liu, D. L. Smith & J. L. McLaughlin

Authors
  1. K. J. Mikolajczak
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  2. R. V. Madrigal
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  3. J. K. Rupprecht
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  4. Y. -H. Hui
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  5. Y. -M. Liu
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  6. D. L. Smith
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  7. J. L. McLaughlin
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Mikolajczak, K.J., Madrigal, R.V., Rupprecht, J.K. et al. Sylvaticin: A new cytotoxic and insecticidal acetogenin fromRollinia sylvatica (Annonaceae). Experientia 46, 324–327 (1990). https://doi.org/10.1007/BF01951779

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  • DOI: https://doi.org/10.1007/BF01951779

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