Summary
Topical application of the tumour promoter 12-0-tetradecanoyl-phorbol-13-acetate to skin caused a marked enhancement of mitotic acitivity both in mice maintained on a complete diet or on a vitamin B6-deficient diet.
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Acknowledgment. The author thanks Mr P. Daenke for excellent technical assistance.
This investigation was supported by the Australian Research Grants Committee and the Australian Tobacco Research Foundation.
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Murray, A.W. Induction of epidermal cell proliferation by a tumour promoter in vitamin B6-deficient mice. Experientia 34, 691 (1978). https://doi.org/10.1007/BF01947260
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DOI: https://doi.org/10.1007/BF01947260