Summary
DevelopingBufo arenarum embryos were treated during gastrulation with cadmium chloride in concentrations ranging from 6×10−7 to 1.5×10−5 M Cd++ at 20 and 30°C. Initial failures at gastrulation result mainly in axial incurvations, microcephaly, hydropsy and abnormal tail formation. The higher temperature has a dual effect: at high concentrations of Cd early malformations are significantly increased, whereas at low concentrations the higher temperature prevents alterations.
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The authors are grateful to Dr Guillermo Jaim Etcheverry for helpful suggestions in the preparation of the manuscript. The electron microscopy work was done in the SEM unit of CONICET (Argentina) with the skillful technical assistence of Jorge Hofman. The work was partially supported by a grant from the Comisión de Investigaciones Científicas (CIC), Prov. de Buenos Aires (Argentina) and CONICET.
Fellow of the CIC.
Member of the Carrera del Investigador Científico Tecnológico (CIC).
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Perez-Coll, C.S., Herkovits, J. & Salibián, A. Teratogenic effects of cadmium onBufo arenarum during gastrulation. Experientia 42, 1174–1176 (1986). https://doi.org/10.1007/BF01941299
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DOI: https://doi.org/10.1007/BF01941299