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Sodium pump: Its importance to intercellular communication in heart fibres

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Summary

The effect of ouabain on the electrical coupling of canine Purkinje cells was investigated. It was found that the glycoside decreases cell communication through an increase in junctional resistance, what supports the view2 that the sodium pump has an important role on the control of cell communication.

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Authors and Affiliations

  1. Department of Pharmacology, Medical Sciences Campus, U. P. R., G. P. O. Box 5067, 00936, San Juan, Puerto Rico, USA

    W. C. de Mello

Authors
  1. W. C. de Mello
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Additional information

This work was supported by Grant No. HL-10897 from the National Heart and Lung Institute, Bethesda, Maryland; from the P.R. Heart Association and from the General Research Support Grant.

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de Mello, W.C. Sodium pump: Its importance to intercellular communication in heart fibres. Experientia 32, 355–357 (1976). https://doi.org/10.1007/BF01940836

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