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Uncoupling of heart cells produced by intracellular sodium injection

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Résumé

L'influence de l'augmentation de la teneur en Na+ intracellulaire sur le processus de communication entre les cellules cardiaques du lapin est étudiée. Une suppression de la communication électrique est provoquée par l'injection de Na+ dans la cellule. Ce résultat est probablement expliqué par une augmentation de la concentration en Ca2+ intracellulaire, subséquente à l'injection de Na+ et par une diminution de la perméabilité des jonctions intercellulaires.

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References

  1. H. J. Schatzmann andF. J. Vincenzl, J. Physiol., Lond.201, 369 (1969).

    Google Scholar 

  2. H. Reuter andN. Seitz, J. Physiol., Lond.195, 451 (1968).

    Google Scholar 

  3. P. F. Baker, M. P. Blaustein, A. L. Hodgkin andR. A. Steinhardt, J. Physiol., Lond.200, 431 (1969).

    Google Scholar 

  4. J. B. Bassingthwaighte andH. Reuter, inElectrical Phenomena in the Heart (Ed.W. C. De Mello; Academic Press, New York 1972), p. 353.

    Google Scholar 

  5. P. F. Baker andM. P. Blaustein, Biochim. biophys. Acta,150, 167 (1968).

    PubMed  Google Scholar 

  6. W. R. Loewenstein, M. Nakas andS. J. Socolar, J. gen. Physiol.5, 1865 (1967).

    Article  Google Scholar 

  7. W. C. De Mello, inElectrical Phenomena in the Heart (Ed.W. C. De Mello; Academic Press, New York 1972), p. 346.

    Google Scholar 

  8. W. Loewenstein, Perspect. Biol. Med.11, 260 (1968).

    PubMed  Google Scholar 

  9. W. C. De Mello, Proc. of the 5th Congr. on Pharmacology 1972, p. 55.

  10. W. C. De Mello, Fedn. Proc.33, 445 (1974).

    Google Scholar 

  11. W. L. Nastuk, Fedn. Proc.12, 102 (1953).

    Google Scholar 

  12. J. del Castillo andB. Katz, J. Physiol., Paris128, 157 (1955).

    Google Scholar 

  13. Supported by Grant No. HE-10897 from National Heart Institute.

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Authors and Affiliations

  1. Department of Pharmacology, Medical Sciences Campus, U.P.R., G.P.O. Box 5067, 00936, San Juan, Puerto Rico, USA

    W. C. de Mello

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  1. W. C. de Mello
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de Mello, W.C. Uncoupling of heart cells produced by intracellular sodium injection. Experientia 31, 460–462 (1975). https://doi.org/10.1007/BF02026379

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  • DOI: https://doi.org/10.1007/BF02026379

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