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Phaeomelanic pigments from a human melanoma

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  • Chimica, Biochimica
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Summary

The pigments in melanomas from 2 patients were studied with regard to solubility and chemical composition. Melanoma pigment from a patient with red-blonde hair was alkali-soluble and contained 9 or 10% sulfur and was thus of phaeomelanic type. Melanoma pigment from a patient with red-brown hair was insoluble in 0.2N NaOH. Its sulfur content was 6%. This pigment was eumelanic with regard to solubility characteristics but the sulfur content was higher than previously observed for eumelanin.

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Author notes

  1. H. Rorsman

    Present address: Department of Dermatology, University of Lund, Lasarettet, S-221 85, Lund, Sweden

Authors and Affiliations

  1. Department of Organic Chemistry, University of Naples, Napoli, Italy

    G. Prota, H. Rorsman, A. -M. Rosengren & E. Rosengren

  2. Department of Dermatology, University of Lund, Lasarettet, S-221 85, Lund, Sweden

    G. Prota, A. -M. Rosengren & E. Rosengren

  3. Department of Biochemistry, University of Lund, Lasarettet, S-221 85, Lund, Sweden

    G. Prota, H. Rorsman, A. -M. Rosengren & E. Rosengren

  4. Department of Pharmacology, University of Lund, Lasarettet, S-221 85, Lund, Sweden

    G. Prota, H. Rorsman, A. -M. Rosengren & E. Rosengren

Authors
  1. G. Prota
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  2. H. Rorsman
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  3. A. -M. Rosengren
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  4. E. Rosengren
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Additional information

Supported by grants from the Swedish Cancer Society (No. 626-B75-04XA), the Swedish Medical Research Council (No. B76-04X-00056-12), and the Walter, Ellen, and Lennart Hesselman Foundation for Scientific Research. ProfessorProta was a visiting scientist of the Swedish Cancer Society (No. 626-B75-04U).

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Prota, G., Rorsman, H., Rosengren, A.M. et al. Phaeomelanic pigments from a human melanoma. Experientia 32, 970–971 (1976). https://doi.org/10.1007/BF01933916

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