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Linear accelerator and Greitz-Bergstrom's head fixation system in radiosurgery of single cerebral metastases. A report of 86 cases

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Summary

Between 1984 and 1991 86 patients with single cerebral metastases underwent linear accelerator radiosurgery using the atraumatic and reproducible Greitz-Bergström head-fixation device. Routine one-month follow-up documented disappearance of the tumour in 16 patients, with resolution of the oedema and ventricular shift. Shrinkage of the metastasis occurred in 51 patients. In 9 patients the tumour remained stable, in 7 there was progression of tumour size. Among the patients showing shrinkage of the tumour or unchanged tumour volume, repeated radiosurgery resulted in disappearance of the metastasis in 5 and further shrinkage in 28. In 14 patients routine stereotacitc CT follow-up study led to the detection of a new metastasis, again treated with excellent results. Local recurrence occurred in 2 patients and radiation necrosis in the target area in 5 patients. Radiosurgery thus proves to be an appropriate alternative to surgery. The versatility of our non-invasive and painless method permits CT staging (which we consider essential) without hospitalization of the patient.

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References

  1. Backhand EO (1979) Stereotactic radiosurgery in intracranial tumours and vascular malformations. In: Advances and technical standards in neurosurgery, Vol 6. Springer, Wien New York

    Google Scholar 

  2. Coffey RJ, Flickinger JC, Bissonette DJet al (1991) Radiosurgery for solitary brain metastases using the Cobalt-60 gamma unit: methods and results in 24 patients. Int J Radiat Oncol Biol Phys 20: 1287–1295

    PubMed  Google Scholar 

  3. Colombo F, Benedetti A, Casentini Let al (1989) Linear accelerator radiosurgery of arteriovenous malformations. Neurosurgery 24: 833–840

    PubMed  Google Scholar 

  4. Greitz T, Bergström M, Kingsley Det al (1980) Head fixation system for integration of radiodiagnostic and therapeutic procedures. Neuroradiology 19: 1–6

    PubMed  Google Scholar 

  5. Kelly PJ, Kall BA, Goerss SJ (1988) Results of computed tomography-based computer-assisted stereotactic radiosurgery of metastatic intracranial tumours. Neurosurgery 22: 7–17

    PubMed  Google Scholar 

  6. Kjellberg RN, Hanamura T, Davis KRet al (1983) Bragg peak proton-beam therapy for arteriovenous malformations of the brain. N Engl J Med 309: 269–274

    PubMed  Google Scholar 

  7. Kooy HM, Nedzi LA, Loeffler JSet al (1991) Treatment planning for stereotactic radiosurgery of intracranial lesions. Int J Radiat Oncol Biol Phys 21: 683–693

    PubMed  Google Scholar 

  8. Lindquist C (1989) Gamma knife surgery for recurrent solitary metastasis of a cerebral hypernephroma: case report. Neurosurgery 25: 802–804

    PubMed  Google Scholar 

  9. Loeffler JS, Alexander III E, Siddon RLet al (1989) Stereotactic radiosurgery for intracranial arteriovenous malformations using a standard linear accelerator. Int J Radiat Oncol Biol Phys 17: 673–677

    PubMed  Google Scholar 

  10. Lutz W, Winston KR, Maleki N (1988) A system for stereotactic radiosurgery with a linear accelerator. Int J Radiat Oncol Biol Phys 14: 373–381

    PubMed  Google Scholar 

  11. Mirri MA, Pavin G, Schinaia G (1990) Radiochirurgia delle metastasi cerebrali. Riv Neuroradiol 3: 291–298

    Google Scholar 

  12. Norén G, Arndt J, Hindmarsh T (1983) Stereotactic radiosurgery in cases of acoustic neurinoma: further experiences. Neurosurgery 13: 12–22

    PubMed  Google Scholar 

  13. Patchell RA, Cirrincione C, Thaler HTet al (1986) Single brain metastases: surgery plus radiation or radiation alone. Neurology 36: 447–453

    PubMed  Google Scholar 

  14. Patchell RA, Tibbs PA, Walsh JWet al (1990) A randomized trial of surgery in the treatment of single metastases to the brain. N Engl J Med 322: 494–500

    PubMed  Google Scholar 

  15. Saloman M (1990) Metastatic brain tumours. Diagnostic and therapeutic management. Contemp Neurosurg 26: 1–5

    Google Scholar 

  16. Sturm V, Kober B, Höver KHet al (1987) Stereotactic percutaneous single dose irradiation of brain metastases with a linear accelerator. Int J Radiat Oncol Biol Phys 13: 279–282

    PubMed  Google Scholar 

  17. Valentino V (1988) Radiosurgery in cerebral tumours and AVM. Acta Neurochirur (Wien) [Suppl] 42: 193–197

    Google Scholar 

  18. Valentino V (1992) Radiochirurgia: work in progress. Riv Neuroradiol 5: 95–106

    Google Scholar 

  19. Valentino V (1991) Postoperative radiosurgery of pituitary adenomas. J Neurosurg Sci 4: 207–211

    Google Scholar 

  20. Valentino V (1992) Radiosurgery in medulloblastoma. A new perspective. J Neurosurg Sci 5: 507–508

    Google Scholar 

  21. Winston KR, Lutz W (1988) Linear accelerator as a neurosurgical tool for stereotactic radiosurgery. Neurosurgery 22: 454–463

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Centro di Radiochirurgia, Clinica Flaminia, Rome

    V. Valentino & M. A. Mirri

  2. Dipartimento di Biologia, II Università degli studi di Roma, Rome

    G. Schinaia

  3. Clinica Neurochirurgica dell' Università di Torino, Turin, Italy

    G. Dalle Ore

Authors
  1. V. Valentino
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  2. M. A. Mirri
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  3. G. Schinaia
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  4. G. Dalle Ore
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Valentino, V., Mirri, M.A., Schinaia, G. et al. Linear accelerator and Greitz-Bergstrom's head fixation system in radiosurgery of single cerebral metastases. A report of 86 cases. Acta neurochir 121, 140–145 (1993). https://doi.org/10.1007/BF01809265

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