Sets pooling designs

Abstract

Pooling desings have previously been used for the efficient identification of distinguished elements of a finite setU. Group testing underlies these designs: For any$S \subseteq U$, a binary result is obtainable, indicating whether or not the number of distinguished elements included inS is zero. The current generalization of pooling designs will enable the efficient identification of distinguished subsets of a finite setU. In this case, for any$S \subseteq U$, a binary result is obtainable, indicating whether or not the number of distinguished subsets included inS is zero. Such designs are called sets pooling designs, comprising standard pooling designs in the special case where all the distinguished subsets are elements. The new designs are similar to the standard designs but are subject to new constraints because the set of subsets included inS is its power set. To illustrate the feasibility of constructing sets pooling designs, random, non-adaptive designs are investigated for the special case where all distinguished subsets have the same size. An optimum probability for including an object in a pool is approximated as a function of the size and number of distinguished subsets, adopting the criterion of minimizing the average number of non-distinguished subsets whose status would not be resolved by the pooling design. Deterministic and adaptive designs are also described.