Abstract
The crucial role of homochirality and chiral homogeneity in the self-replication of contemporary biopolymers is emphasized, and the experimentally demonstrated advantages of these chirality attributes in simpler polymeric systems are summarized. The implausibility of life without chirality and hence of a biogenic scenario for the origin of chiral molecules is stressed, and chance and determinate abiotic mechanisms for the origin of chirality are reviewed briefly in the context of their potential viability on the primitive Earth. It is concluded that all such mechanisms would be non-viable, and that the turbulent prebiotic environment would require an ongoing extraterrestrial source for the accumulation of chiral molecules on the primitive Earth. A scenario is described wherein the circularly polarized ultraviolet synchrotron radiation from the neutron star remnants of supernovae engenders asymmetric photolysis of the racemic constituents in the organic mantles on interstellar dust grains, whereupon these chiral constituents are transported repetitively to the primative Earth by direct accretion of the interstellar dust or through impacts of comets and asteroids.
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Addadi, L. and Lahav, M.: 1979, in Walker, D.C. (ed.), Origins of Optical Activity in Nature, Elsevier, New York, pp. 179–192.
Addadi, L., Cohen, M. D., and Lahav, M.: 1979, in Selegny, E. (ed.), Optically Active Polymers, Kluwer Acad. Publ., Dordrecht, Holland, pp. 183–197.
Addadi, L., Berkovitch-Yellin, Z., Weissbuch, I., van Mil, J., Shimon, L. J. W., Lahav, M., and Leiserowitz, L.: 1985,Angew. Chem. Int. Ed. Engl. 24, 466.
Agarwal, V. K., Schutte, W., Greenberg, J. M., Ferris, J. P., Briggs, R., Conner, S., van de Bult, C. E. P. M., and Baas, F.: 1986,Origins of Life 16, 21.
Amariglio, A., Amariglio, H., and Duval, X.: 1968,Helv. Chim. Acta 51, 2110.
Avetisov, V. A. and Goldanskii, V. I.: 1991,BioSystems 25, 141.
Avetisov, V. A., Anikin, S. A., Goldanskii, V. I., and Kuzmin, V. V.: 1985,Dokl. Akad. Nauk SSSR-Biophys. 282, 115.
Avetisov, V. A., Goldanskii, V. I., and Kuzmin, V. V.: 1991,Physics Today 44, 33.
Arrhenius, S.: 1903, in Goldsmith, D. (ed.), The Quest for Extraterrestrial Life, University Science Books, California, 1980, pp. 32–33.
Bada, J. L. and Miller, S. L.: 1987,BioSystems 20, 21.
Balavoine, G., Moradpour, A., and Kagan, H. B.: 1974,J. Am. Chem. Soc. 96, 5152.
Barbier, B. and Brack, A.: 1992,J. Am. Chem. Soc. 114, 3511.
Barron, L. D.: 1987,BioSystems 20, 7.
Blair, N. E. and Bonner, W. A.: 1980,Origins of Life 10, 255.
Blair, N. E. and Bonner, W. A.: 1981,Origins of Life 11, 331.
Blair, N. E., Dirbas, F. M., and Bonner, W. A.: 1981,Tetrahedron 37, 27.
Blout, E. R., Doty, P., and Yang, J. T.: 1957,J. Am. Chem. Soc. 79, 749.
Blout, E. R. and Idelson, M.: 1956,J. Am. Chem. Soc. 78, 3857.
Bondy, S. C. and Harrington, M. E.: 1979,Science 203, 1243.
Bonner, W. A.: 1972, in Ponnamperuma, C. (ed.), Exobiology, North-Holland, Amsterdam, pp. 170–234.
Bonner, W. A.: 1988, in Eliell, E. L. and Wilen, S. H. (eds.), Topics in Stereochemistry, Vol. 18, John Wiley & Sons, New York, pp. 1–96.
Bonner, W. A.: 1990,Origins Life Evol Biosphere 20, 1.
Bonner, W. A.: 1991,Origins Life Evol. Biosphere 21, 59–111.
Bonner, W. A.: 1992,Origins Life Evol. Biosphere 21, 407–420.
Bonner, W. A.: 1994,Origins Life Evol. Biosphere 24, 63.
Bonner, W. A. and Flores, J. J.: 1973,Curr. Mod. Biol. 5, 103.
Bonner, W. A. and Flores, J. J.: 1975,Origins of Life 6, 187.
Bonner, W. A. and Lemmon, R. M.: 1978,Bioorg. Chem. 7, 175.
Bonner, W. A. and Rubenstein, E.: 1990, in Ponnamperuma, C. and Eirich, F. R. (eds.), Prebiological Self Organization of Matter, A. Deepak Publishing, Hampton, Virginia, pp. 35–50.
Bonner, W. A., Blair, N. E., and Lemmon, R. M.: 1979a,Origins of Life 9, 279.
Bonner, W. A., Kavasmaneck, P. R., Martin, F. S., and Flores, J. J.: 1974,Science 186, 143.
Bonner, W. A., Kavasmaneck, P. R., Martin, F. S., and Flores, J. J.: 1975,Origins of Life 6, 367.
Bonner, W. A., Blair, N. E., Lemmon, R. M., Flores, J. J., and Pollock, G. E.: 1979b,Geochim. Cosmochim. Acta 43, 1841.
Brack, A. and Spach, G.: 1979,J. Mol. Evol. 13, 35.
Brack, A. and Spach, G.: 1980,J. Mol. Evol. 15, 231.
Brack, A. and Spach, G.: 1981,Origins of Life 11, 135.
Briggs, R., Ertem, G., Ferris, J. P., Greenberg, J. M., McCain, P. J., Mendoza-Gomez, C. X., and Schutte, W.: 1992,Orig. Life Evol. Biosphere 22, 287.
Calvin, M.: 1969, Chemical Evolution, Oxford University Press, Oxford, pp. 149–152.
Chenchaiah, P. C, Holland, H. L., and Richardson, M. F.: 1982, J. Chem. Soc, Chem. Commun., 436.
Chyba, C. F.: 1990,Nature 343, 129.
Chyba, C. and Sagan, C: 1992,Nature 355, 125.
Degens, E. T., Matheja, J., and Jackson, T. A.: 1970,Nature 227, 492.
Delsemme, A.: 1991–1992,Origins Life Evol. Biosphere 21, 279.
Engel, M. H., Macko, S. A., and Silfer, J. A.: 1990,Nature 348, 47.
Figureau, A., Duval, E., and Boukenter, A.: 1992, LYCEN 9244, preprint.
Frank, F. C: 1953,Biochem. Biophys. Acta 11, 459.
Friebele, E., Shimoyama, A., Hare, P. E., and Ponnamperuma, C, 1981,Origins of Life 11, 173.
Frondel, C.: 1978,Amer. Minerol. 63, 22.
Goldanskii, V. I. and Kuzmin, V. V.: 1988, Z.Phys. Chem. 269, 216.
Green, B. S., Lahav, M., and Schmidt, G. M. J.: 1975,Mol. Cryst. Liq. Cryst. 29, 187.
Green, B. S., Lahav, M., and Rabinovich, D.: 1979,Acc. Chem. Res. 12, 191.
Greenberg, J. M.: 1984,Sci. Am. 250, 124.
Greenberg, J. M.: 1992, Private communication.
Greenberg, J. M., Zhao, N., and Hage, J.: 1989,Ann. Phys. Fr. 14, 103.
Havinga, E.: 1954,Biochem. Biophys. Acta 13, 171.
Huebner, W. F. and Boice, D. C.: 1991–1992,Origins Life Evol. Biosphere 21, 299.
Idelson, M. and Blout, E. R.: 1958,J. Am. Chem. Soc. 80, 2387.
Jackson, T. A.: 1971,Chem. Geol. 7, 295.
Jaeger, F. M.: 1930, Optical Activity and High Temperature Measurements, McGraw-Hill, New York, pp. 75–76.
Joyce, G. F., Visser, G. M., van Boeckel, C. A. A., van Boom, J. H., Orgel, L. E., and van Westrenen, J.: 1984,Nature 310, 602.
Kagan, H. B. and Fiaud, J. C.: 1988, in Eliel, E. L. and Wilen, S. H. (eds.), Topics in Stereochemistry. Vol. 18, John Wiley & Sons, New lYork, pp. 249–330.
Karagounis, G. and Coumoulos, G.: 1938,Nature 142, 162.
Keszthelyi, L.: 1984,Origins of Life 14, 375.
Keszthelyi, L., Czege, J., Fajszi, C., Posfai, J., and Goldanskii, V. I.: 1979, in Walker, D. C. (ed.), Origins of Optical Activity in Nature, Elsevier, New York, pp. 229–244.
Khasanov, M. M. and Gladyshev, G. P.: 1980,Origins of Life 10, 247.
Kuhn, W. and Braun, E.: 1929,Naturwissenschaften 17, 227.
Kulkarni, R. K. and Morawetz, H.: 1961,J. Polym. Sci. 54, 491.
Kvenvolden, K., Lawless, J. G., and Ponnamperuma, C: 1971,Proc. Nat. Acad. Sci. 68, 486.
Lahav, M., Laub, F., Gati, E., Leiserowitz, L., and Ludmer, Z.: 1976,J. Am. Chem. Soc. 98, 1620.
MacDermott, A. J. and Tranter, G. E.: 1989,Croat. Chem. Acta. 62, 165.
Maher, K. A. and Stevenson, D. J.: 1988,Nature 331, 612.
Marcus, J. N. and Olsen, M. A.: 1991, in Newburn, R. L., Neugebauer, M., and Rahe, J. (eds.), Comets in the Post-Bailey Era, Kluwer Acad. Publ., Dordrecht, The Netherlands, pp. 439–462.
Mason, S. F.: 1986,Nuov. J. Chem. 10, 739.
Mason, S. F. and Tranter, G. E.: 1985,Proc. Roy. Soc. London A 397, 45.
McCullough, J. J. and Lemmon, R. M.: 1974,J. Mol. Evol. 3, 57.
Miller, S. L. and Orgel, L. E.: 1974, The Origins of Life on Earth, Prentice-Hall, Inc., Englewood Cliffs, N. J., pp. 166–174.
Morowitz, H. J.: 1969,J. Theor. Biol. 25, 491.
Nash, J. M.: 1993, Oct. 11,TIME 142, 68.
Oberbeck, V. R. and Aggarwal, H.: 1991–1992,Origins Life Evol. Biosphere 21, 317.
Oberbeck, V. R. and Fogleman, G.: 1989,Origins Life Evol. Biosphere 19, 549.
Oberbeck, V. R. and Fogleman, G.: 1990,Origins Life Evol. Biosphere 20, 181.
Oró, J.: 1961,Nature 190, 389.
Oró, J., Nakaparksin, S., Lichtenstein, H., and Gil-Av, E.: 1971,Nature 230, 107.
Pace, N. R.: 1991,Cell 65, 531.
Palache, C, Berman, H. and Frondel, C: 1962, Dana's System of Minerology., 7th Ed., Vol. III, John Wiley & Sons, New York, pp. 16–17.
Pasteur, L.: 1860, Researches on Molecular Asymmetry, Univ. Chicago Press, Chicago, 1914, pp. 29, 45.
Ramamurthy, V. and Venkatesan, K.: 1987,Chem. Rev. 87, 433.
Rich, A.: 1993, Private communication, August 5.
Rubenstein, E., Bonner, W. A., Noyes, H. P., and Brown, G. S.: 1983,Nature 306, 118.
Sagan, C: 1974,Origins of Life 5, 497.
Salam, A.: 1991,J. Mol. Evol. 33, 105.
Scheffer, J. R. and Pokkuluri, P. R.: 1991, in Ramamurthy, V. (ed), Photochemistry in Organized & Constrained Media, VCH Publishers, Inc., New York; pp. 186–246.
Shapiro, R.: 1986, Origins — a Skeptics Guide to the Creation of Life on Earth, Summit Books, New York, pp. 98–116.
Sleep, N. H., Zahnle, K. J., Kasting, J. F., and Morowitz, H. J.: 1989,Nature 343, 139.
Takahashi, F., Tomii, K., and Takahashi, H.: 1986,Electrochim. Acta 31, 127.
Terent'ev, A. P. and Klabunovskii, E. I.: 1957, in Clark, F. and Synge R. L. M. (eds), The Origin of Life on Earth, Pergamon Press, New York, 1959, pp. 95–105.
Thiemann, W.: 1974,J. Mol. Evol. 4, 85.
Ulbricht, T. L. V.: 1959,Quart. Rev. 13, 48.
Vaida, M., Popovitz-Biro, R., Leiserowitz, L, and Lahav, M.: 1991, in Ramamurthy, V. (ed), Photochemistry in Organized & Constrained Media, VCH Publishers, Inc., New York; pp. 248–302.
Vaida, M., Shimon, L. J. W., van Mil,J., Ernst-Cabrera, K., Addadi, L., Leiserowitz, L., and Lahav, M.: 1989,J. Am. Chem. Soc. 111, 1029.
Wald, G.: 1957,Ann. N. Y. Acad. Sci. 69, 353.
Waldrop, M. M.: 1990,Science 250, 1078.
Weber, A. L.: 1989,Origins Life Evol. Biosphere 19, 7.
Weingarten, H.: 1958,J. Am. Chem. Soc. 80, 352.
Weissbuch, I., Addadi, L., Leiserowitz, L., and Lahav, M: 1988,J. Am. Chem. Soc. 110, 561.
Weissbuch, I., Addadi, L., Berkovitch-Yellin, Z., Gati, E. Lahav, M., and Leiserowitz, L.: 1984,Nature 310, 161.
Yamagata, Y.: 1966,J. Theor. Biol. 11, 495.
Youatt, J. B. and Brown, R. D.: 1981,Science 212, 1145.
Zhang, S., Holmes, T., Lockshin, C., and Rich, A.: 1993,Proc. Natl. Acad. Sci. USA 90, 3334.
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Bonner, W.A. Chirality and life. Origins Life Evol Biosphere 25, 175–190 (1995). https://doi.org/10.1007/BF01581581
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DOI: https://doi.org/10.1007/BF01581581