Abstract
The human gene for parathyroid hormone (PTH) was chromosomally mapped using human-rodent hybrids and Southern filter hybridization of cell hybrid DNA. A recombinant DNA probe containing human PTHcDNA insert (pPTHm122) hybridized to a 3.7-kb fragment in human DNA cleaved with the restriction enzyme EcoRI. By correlating the presence of this fragment in somatic cell hybrid DNA with the human chromosomal content of the hybrid cells, the PTHgene was mapped to the short arm of the chromosome 11.
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Naylor, S.L., Sakaguchi, A.Y., Szoka, P. et al. Human parathyroid hormone gene (PTH) is on short arm of chromosome 11. Somat Cell Mol Genet 9, 609–616 (1983). https://doi.org/10.1007/BF01574261
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DOI: https://doi.org/10.1007/BF01574261