Skip to main content
Log in

Location ofMls locus on mouse chromosome 1

  • Published:
Immunogenetics Aims and scope Submit manuscript

Abstract

Linkage between theMls locus and the chromosome 1 markersDip-1 andald was detected using two sets of recombinant inbred strains. Linkage betweenMls andDip-1 was confirmed in the fifth and sixth backcross generations of an incipient congenic strain. The AKXL data indicate that the gene order isDip-1-ald-Mls. The recombination frequency betweenald andMls is estimated to be 0.07 ±0.05, based on the AKXL data. The recombination frequency betweenDip-1 andMls is estimated to be 0.18 ±0.04, based on all the available data.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Festenstein, H.: Immunogenetic and biological aspects of in vitro lymphocyte allotransformation (MLR) in the mouse.Transplant. Rev. 15:62–88, 1973

    Google Scholar 

  • Festenstein, H.: TheMls system.Transplant. Proc. 8:339–342, 1976

    Google Scholar 

  • Festenstein, H., Sachs, J.A., and Oliver, R.T.D.: Genetic studies of the mixed lymphocyte reaction in H-2-identical mice.Proceedings of the Symposium on Immunogenetics of the H-2 System, Liblice-Prague, 1970, pp. 170–177, Karger, Basel, 1971

    Google Scholar 

  • Haidane, J.B.S. and Waddington, C.H.: Inbreeding and linkage.Genetics 16:357–374, 1931

    Google Scholar 

  • Henderson, N.S.: Isozymes and genetic control of NADP-malate dehydrogenase in mice.Arch. Biochem. Biophys. 117:28–33, 1966

    Google Scholar 

  • Taylor, B.A., Bailey, D.W., Cherry, M., Riblet, R., and Weigert, M.: Genes for immunoglobulin heavy chain and serum prealbumin protein are linked in mouse.Nature 256:644–646, 1975

    Google Scholar 

  • Taylor, B.A. and Meier, H.: Mapping the adrenal lipid depletion gene of the AKR/J mouse strain.Genet. Res. 26:307–312, 1976

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Festenstein, H., Bishop, C. & Taylor, B.A. Location ofMls locus on mouse chromosome 1. Immunogenetics 5, 357–361 (1977). https://doi.org/10.1007/BF01570493

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01570493

Keywords

Navigation