Skip to main content
Log in

Polychlorinated biphenyls in human adipose tissue

  • Published:
Bulletin of Environmental Contamination and Toxicology Aims and scope Submit manuscript

Summary

Among the chlorinated hydrocarbon synthetic pollutants in the environment, polychlorinated biphenyls represent a class of compounds possessing mammalian toxicity and recently found to be present as residues in the tissues of various wildlife species, although they are not in use as biocidal compounds. Two human adipose tissue samples examined by combined gas chromatography-mass spectrometry were shown to contain substantial quantities of polychlorinated biphenyls ranging from pentachlorobiphenyl to decachlorobiphenyl and including at least fourteen isomers and chlorine homologs. Although the origin of the PCB compounds found in the adipose tissue is ununknown, the data are presented as a description of the gas chromatographic-mass spectrophotometric behavior of PCB and of the analytical methodology applicable to the analysis of these compounds in human tissues by gas chromatography-mass spectrometry.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. RISEBROUGH, R.W., RIECHE, P., HERMAN, S.G., PEAKALL, D.B., and KIRVIN, M.N. Nature 220, 1098 (1968).

    Article  CAS  Google Scholar 

  2. JENSEN, S. New Scientist 32, 612 (1966).

    Google Scholar 

  3. HOLMES, D.C., SIMMONS, J.H., and TATTON, J.O'G. Nature 216, 227 (1967).

    Article  CAS  Google Scholar 

  4. LICHTENSTEIN, E.P., SCHULZ, K.R., FUHREMANN, T.W., and LIANG, T.T. J. Econ. Entomol. 62, 761 (1969).

    CAS  Google Scholar 

  5. REYNOLDS, L.M. Bull. Environ. Contam. Toxicol. 4, 128 (1969).

    Article  CAS  Google Scholar 

  6. RISEBROUGH, R.W., RIECHE, P., and OLCOTT, H.S. Bull. Environ. Contam. Toxicol. 4, 192 (1969).

    Article  CAS  Google Scholar 

  7. WIDMARK, G. J. Assoc. Offic. Anal. Chemists 50, 1069 (1967).

    Google Scholar 

  8. HOLDEN, A.V. and MARSDEN, K. Nature 216, 1274 (1967).

    Article  CAS  Google Scholar 

  9. ERRO, F., BEVENUE, A., and BECKMAN, H. Bull. Environ. Contam. Toxicol. 2, 372 (1967).

    Article  CAS  Google Scholar 

  10. BIROS, F.J. and WALKER, A.C. In preparation.

  11. MILLS, P. J. Assoc. Offic. Anal. Chemists 42, 734 (1959); Pesticide Analytical Manual, Vol. I, Sec. 211, Food and Drug Administration, U.S. Department of Health, Education, and Welfare, Washington, D.C., 1969.

    CAS  Google Scholar 

  12. BEYNON, J.H. Mass Spectrometry and Its Applications to Organic Chemistry, p. 298 (1960), Elsevier Publishing Co., New York.

    Google Scholar 

  13. SWEELEY, C.C., ELLIOTT, W.H., FRIES, I., and RYHAGE, R. Anal. Chem. 38, 1549 (1966).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Biros, F.J., Walker, A.C. & Medbery, A. Polychlorinated biphenyls in human adipose tissue. Bull. Environ. Contam. Toxicol. 5, 317–323 (1970). https://doi.org/10.1007/BF01539944

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01539944

Keywords

Navigation