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Chromosomal assignment of human sequences encoding arginine vasopressin-neurophysin II and growth hormone releasing factor

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Somatic Cell and Molecular Genetics

Abstract

Complementary DNA clones encoding bovine vasopressin and human pancreas growth hormone releasing factor have been used to map homologous sequences in the human genome. Assignment of both cloned sequences to human chromosome 20 was accomplished by hybridization of insert DNAs to a panel of human-rodent somatic cell hybrids. Both these probes have been used to examine the structure of their respective genes in DNA from various individuals. No restriction fragment variants for growth hormone releasing factor have yet been found. Analysis of populations for restriction fragment length polymorphisms associated with disease states involving arginine vasopressin is underway.

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Literature cited

  1. Land, H., Schutz, G., Schmale, H., and Richter, D. (1982).Nature 295:299–303.

    PubMed  Google Scholar 

  2. Schmale, H., Heinsohn, S., and Richter, D. (1983).EMBO J. 2(5):763–767.

    PubMed  Google Scholar 

  3. Gubler, U., Monahan, J.J., Lomedico, P.T., Bhatt, R.S., Collier, K.J., Hoffman, B.J., Bohlen, P., Esch, F., Ling, N., Zeytin, F., Brazeau, P., Poonian, M.S., and Gage, L.P. (1983).Proc. Natl. Acad. Sci. U.S.A. 80:4311–4313.

    PubMed  Google Scholar 

  4. Margo, K.E., Vale, W., Rivier, J., Rosenfeld, M.G., and Evans, R.M. (1983).Nature 306:86–88.

    PubMed  Google Scholar 

  5. Anderson, K.E., Arner, B., Furst, E., and Hedner, P. (1974).Acta Med. Scand. 195:17–23.

    PubMed  Google Scholar 

  6. Pender, C.B., and Fraser, F.C. (1953).J. Pediatr. 11:246–254.

    Google Scholar 

  7. Martin, F.I.R. (1959).Q.J. Med. 28:573–582.

    PubMed  Google Scholar 

  8. Braverman, L.E., Mancini, J.P., and Goldrick, D.M. (1965).Ann. Intern. Med. 63:503–508.

    PubMed  Google Scholar 

  9. Forsman, H. (1955).Am. J. Hum. Genet. 7:21–27.

    PubMed  Google Scholar 

  10. Green, J.R., Buchan, G.C., Alvord, E.C., and Swanson, A.G. (1967).Brain 90:707.

    PubMed  Google Scholar 

  11. Gunnt, T., Bortolussi, R., Little, J.M., Anderman, F., Fraser, F.C., and Belmonte, M.M. (1976). J. Pediatr.89:565–570.

    PubMed  Google Scholar 

  12. Schmale, H., and Richter, D. (1984).Nature 308:705–709.

    PubMed  Google Scholar 

  13. Szabo, M., Chu, L. and Frohman, L.A. (1982).Endocrinology 111:1235–1240.

    PubMed  Google Scholar 

  14. Rivier, J., Spiess, J., Thorner, M., and Vale, W. (1982).Nature 300:276–278.

    PubMed  Google Scholar 

  15. Barinaga, M., Yamonoto, G., Rivier, C., Vale, W., Evans, R., and Rosenfeld, M.G. (1983).Nature 306:84–85.

    PubMed  Google Scholar 

  16. Borges, J.L.C., Blizzard, R.M., Gelato, M., Furlanetto, R., Rogol, A.D., Evans, W.S., Vance, M.L., Kaiser, D.L., MacLeod, R.M., Merriam, G.R., Loriaux, D.L., Speiss, J., Rivier, J., Vale, W., and Thorner, M.O. (1983).Lancet 2(8342):119–123.

    PubMed  Google Scholar 

  17. Grossman, A., Savage, M.O., Wass, J.A.H., Lytras, N., Sueiras-Diaz, J., Coy, D.H., and Besser, G.M. (1983).Lancet 2(8342):137–138.

    PubMed  Google Scholar 

  18. Bohlen, P., Brazeau, P., Esch, F., Ling, N., Wehernberg, W.B., and Guillemin, R. (1983).Regul. Pept. 6:343–353.

    PubMed  Google Scholar 

  19. Guillemin, R., Brazeau, P., Bohlen, P., Esch, F., Ling, N.C., and Wehrenberg, W.B. (1982).Science 218:585–587.

    PubMed  Google Scholar 

  20. Donald, L.J., Wang, H.S., Kamali, V., Liebert, L., Rudner-Marion, M., Cameron, E.S., Riddell, D.C., Vust, A., Wrogemann, K., and Hamerton, J.L. (1983).Cytogenet. Cell Genet. 37:453A.

    Google Scholar 

  21. Riddell, D.C., Wang, H.S., Beckett, J., Holden, J.J.A., Mulligan, L., Phillips, A., Simpson, N., Wrogemann, K., Hamerton, J.L. and White, B.N.Cytogenet. Cell Genet. (submitted).

  22. Marmur, J. (1961).J. Mol. Biol. 3:208.

    Google Scholar 

  23. Southern, E.M. (1975).J. Mol. Bol. 98:503–517.

    Google Scholar 

  24. Rigby, P.W.J., Diekmann, M., Rhodes, C., and Berg, P. (1977).J. Mol. Biol. 113:237–251.

    PubMed  Google Scholar 

  25. Denhardt, D.T. (1966).Biochem. Biophys. Res. Commun. 23:641–646.

    PubMed  Google Scholar 

  26. Bohlen, P., Esch, F., Brazeau, P., Ling, N., and Guillemin, R. (1983).Biochem. Biophys. Res. Commun. 116:726–734.

    PubMed  Google Scholar 

  27. Van Dyke, D.L., Jackson, C.F., and Babu, V.R. (1981).Cytogenet. Cell Genet. 32(1–4):324A.

    Google Scholar 

  28. Parks, J.S., Sexton, L.C., Slott, E.F., Mallonee, R.L., and Phillips, J.A. (1984).Pediatr. Res. 18:172A.

    Google Scholar 

  29. Land, H., Grez, M., Ruppert, S., Schmale, H., Rehbein, M., Richter, D., and Schutz, G. (1983).Nature 302:342–343.

    PubMed  Google Scholar 

  30. Ruppert, S., Scherer, G., and Shutz, G. (1984).Nature 308:554–557.

    PubMed  Google Scholar 

  31. Archer, R. (1980).Proc. R. Soc. 210:21–43.

    Google Scholar 

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Authors and Affiliations

  1. Division of Human Genetics, University of Manitoba, R3E OW3, Winnipeg, Manitoba, Canada

    D. Christie Riddell & John L. Hamerton

  2. Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee

    Richard Mallonee & John A. Phillips

  3. Department of Pediatrics, Emory University, 30322, Atlanta, Georgia

    John S. Parks & Laura A. Sexton

Authors
  1. D. Christie Riddell
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  2. Richard Mallonee
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  3. John A. Phillips
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  4. John S. Parks
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  5. Laura A. Sexton
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  6. John L. Hamerton
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Riddell, D.C., Mallonee, R., Phillips, J.A. et al. Chromosomal assignment of human sequences encoding arginine vasopressin-neurophysin II and growth hormone releasing factor. Somat Cell Mol Genet 11, 189–195 (1985). https://doi.org/10.1007/BF01534707

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  • DOI: https://doi.org/10.1007/BF01534707

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