Summary
LH-activity in the 24-hour urine of control subjects and of patients with pituitary tumors were determined before and after hypophysectomy (N=53) by means of ethanol extraction and hemagglutination inhibition tests. No LH-activity was found in 7.5% of the urine of the controls and only 20.3% of the 24-hour urine samples of the pituitary tumor group showed any measurable LH activity. Methodological problems are discussed. The results of these studies are compared with reports previously published in the literature.
Zusammenfassung
Mittels einer fraktionierten Äthanolextraktion und eines Hämagglutinationshemmungstestes werden die LH-Aktivitäten im 24 Std-Urin gesunder Personen und von Patienten mit Hypophysentumoren vor und nach Hypophysektomie (N=53) untersucht. Bei 7,5% der untersuchten 24 Std-Urine von Normalpersonen war keine LH-Aktivität nachweisbar. Nur bei 20,3% der untersuchten 24 Std-Urine der Patienten mit Hypophysentumoren konnte eine meßbare LH-Aktivität nachgewiesen werden. Methodische Probleme werden diskutiert und die Ergebnisse mit bereits aus der Literatur bekannten verglichen.
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Literatur
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Souvatzoglou, A., Bottermann, P., Dirr, E. et al. „Quantitative“ immunochemische LH-Bestimmung im Urin bei Normalpersonen und Patienten mit Hypophysentumorcn. Klin Wochenschr 49, 215–219 (1971). https://doi.org/10.1007/BF01495985
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DOI: https://doi.org/10.1007/BF01495985