Skip to main content
SpringerLink
Log in

Synthesis of 4,5,6-trisubstituted 3-cyanopyridine-2(1H)-thiones based on α-substituted β-diketones

  • Organic Chemistry
  • Published:
Russian Chemical Bulletin Aims and scope

Abstract

5-Substituted 3-cyano-4,6-dimethylpyridine-2(lH)-thiones were synthesized by the re action of a-substituted β-diketones with cyanothioacetamide in the presence of triethyl amine. The compounds synthesized were converted into thieno[2,3-blpyridines by treatment with organic halides and KOH.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. G. Wagner, H. Vieweg, S. Leisner, N. Bohm, U. Krasselt, V. Hanfeld, J. Prantz, and R. Grupe,Pharmazie., 1990,45, 102.

    Google Scholar 

  2. G. E. A. Elgemeie, H. A. Ali, and M. N. Eid,J. Chem. Res., Synop., 1993,7, 256,

    Google Scholar 

  3. P. K. Chiu and M. P. Sammes,Tetrahedron., 1988,44, 3538

    Google Scholar 

  4. H. Adkins, W. Kutz, and D. D. Coffman,J. Am. Chem. Soc., 1930,52, 3212.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 117913, Moscow, Russian Federation

    N. G. Frolova, V. K. Zav'yalova & V. P. Litvinov

Authors
  1. N. G. Frolova
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. V. K. Zav'yalova
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. V. P. Litvinov
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Translated fromlzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 11, pp. 2719–2721, November, 1996.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Frolova, N.G., Zav'yalova, V.K. & Litvinov, V.P. Synthesis of 4,5,6-trisubstituted 3-cyanopyridine-2(1H)-thiones based on α-substituted β-diketones. Russ Chem Bull 45, 2578–2580 (1996). https://doi.org/10.1007/BF01431119

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01431119

Key words

Search

Navigation