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Neuro-rhinosurgical treatment of aesthesioneuroblastoma

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Summary

The results of a combined neuro-rhinosurgical procedure in eight cases of aesthesioneuroblastoma are presented. All patients were suffering from tumours in the advanced stage (stage C according to Kadish). Diagnosis was established by the clinical history, neuroradiological imaging and by endoscopic endonasal biopsy. Contrary to most reports in the literature the authors performed a one step operative removal of the whole tumour mass by a combined transcranial-transbasal approach alone. A second transfacial operation was unnecessary in all our cases. To the best of our knowledge only Loew (see Jakumeit 1971) already in the 1960ties used a comparable one step transcranial approach for tumour removal.

The long-term survival rate in our patients is 50%, a result comparable to reported series in the literature. Mortality is due to early recurrences and metastases within a few months after the initial treatment including post-operative irradiation. Four patients are living without evidence of tumour recurrence 1.5 to 5 years after treatment.

The authors surgical technique is presented in detail and compared with the results of other treatment modalities.

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Authors and Affiliations

  1. Neurochirurgische UniversitÄtsklinik, Erlangen-Nürnberg, Germany

    R. Fahlbusch & U. Neubauer

  2. Hals-Nasen-Ohren-Klinik, Erlangen-Nürnberg, Germany

    M. Wigand & M. Weidenbecher

  3. Pathologisches Institut, Erlangen-Nürnberg, Germany

    G. Röckelein & P. Thierauf

  4. Strahlentherapeutische Klinik der UniversitÄt, Erlangen-Nürnberg, Germany

    R. Sauer

Authors
  1. R. Fahlbusch
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  2. U. Neubauer
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  3. M. Wigand
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  4. M. Weidenbecher
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  5. G. Röckelein
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  6. P. Thierauf
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  7. R. Sauer
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Fahlbusch, R., Neubauer, U., Wigand, M. et al. Neuro-rhinosurgical treatment of aesthesioneuroblastoma. Acta neurochir 100, 93–100 (1989). https://doi.org/10.1007/BF01403592

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