Summary
Giant cell tumours of the brain are commonly a) monstrocellular sarcomas, b) giant cell glioblastomas or gliosarcomas, or c) “giant cell gliomas”,i.e. gliomas characterized by many atypical, giant-sized cells with monstrous nuclei. This last group is commonly found in the temporal region and should not be mistaken for a) and b), because, in spite of their “malignant” appearance, these tumours can present benign biological behaviour.
Three such cases are described. In two cases the patients received postoperatively neither radio- nor chemotherapy: seven and three years respectively after operation no signs of recurrences were present. A third patient died within two years after operation. However, his tumour had histological signs of malignancy.
The importance of exact histological diagnosis is stressed. This prevents misinterpretations in estimating the efficacy of postoperative therapy.
Similar content being viewed by others
References
Dill, R., Gullotta, F., Pathomorphologische Befunde bei Temporallappenepilepsien. Ein Beitrag zur Frage des Ganglioglioms. Schweiz. Arch. Neurol. Neurochir. Psychiat.106 (1970), 241–255.
Escalona Zapata, J., El astrocitoma gigantocelular subependimario y su relación con la esclerosis tuberosa. Trab. Inst. Cajal Invest. Biol.55 (1963), 173–195.
Gullotta, F., Zur in vitro-Diagnostik gliös-mesenchymaler Mischgeschwülste. Dtsch. Z. Nervenheilk.186 (1964), 323–335.
Gullotta, F., Cervos Navarro, J., Serra, J. P., Istologia, ultrastruttura e comportamento in vitro di un ganglioglioma cerebrale. Acta neurologica (Naples)25 (1970), 188–196.
Rack, J. H., Yates, P. O., Ependymal glioblastoma of giant-cell type. J. Path. Bact.78 (1959), 151–156.
Zülch, K. J., In: Biologie und Pathologie der Hirngeschwülste. Handbuch der Neurochirurgie, Bd. III (Olivecrona, H., Tönnis, W., Herausg.). Berlin-Göttingen-Heidelberg: Springer. 1956.
Zülch, K. J., On the definition of the polymorphous oligodendroglioma. In: Classification of Brain Tumours, pp. 166–172 (Zülch, K. J., Woolf, A. L., eds.). Acta Neurochir. (Wien), Suppl.10. Wien-New York: Springer. 1964.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Gullotta, F., Casentini, L. & Neumann, J. Giant cell gliomas of the temporal lobe. Acta neurochir 54, 25–31 (1980). https://doi.org/10.1007/BF01401940
Issue Date:
DOI: https://doi.org/10.1007/BF01401940