Abstract
Between 1960 and 1979, three studies were conducted in the Baltimore Standard Metropolitan Statistical Area to ascertain the incidence rates of first hospitalizations for ulcerative colitis and Crohn's disease. The age-adjusted rates per 100,000 population for the 1977–1979 survey for ulcerative colitis in white and nonwhite males and females were 2.92, 1.79, 1.29, and 2.90, respectively; the Crohn's disease rates were 3.39, 3.54, 1.29, and 4.08, respectively. In Baltimore the age-adjusted rate for Crohn's disease has increased to exceed the ulcerative colitis rate for whites of both sexes and nonwhite females. The ulcerative colitis and Crohn's disease rates for nonwhite males are similar. The rate for white males exceeds that for nonwhite males for both ulcerative colitis and Crohn's disease, but the converse is true for females. Females have higher rates than males for Crohn's disease in both color groups and for ulcerative colitis among nonwhites. White ulcerative colitis rates are higher for males than for females. From the first to the second surveys, the white male and female rates for ulcerative colitis converge with increasing male and decreasing female rates, but then both decline from the second to the third surveys. For Crohn's disease, the age-adjusted rates increased for whites of both sexes and nonwhite females from the first to second surveys. The Crohn's disease rates appeared to stabilize for whites of both sexes between the second and present surveys, but they increased for nonwhites of both sexes. Trends in age-adjusted rates for other areas are also discussed.
Similar content being viewed by others
References
Monk M, Mendeloff AI, Siegel CI, Lilienfeld AM: An epidemiological study of ulcerative colitis and regional enteritis among adults in Baltimore. I. Hospital incidence and prevalence, 1960 to 1963. Gastroenterology 53:198–210, 1967
Garland CF, Lilienfeld AM, Mendeloff AI, Markowitz JA, Terrell KB, Garland FC: Trend in incidence rates of ulcerative colitis and Crohn's disease in Baltimore. (submitted)
Lilienfeld AM, Lilienfeld DE: Foundations of Epidemiology, 2nd ed, Oxford University Press, New York, 1980, p 358
Devlin HB, Datta D, Dellipiani AW: The incidence and prevalence of inflammatory bowel disease in North Tees Health District. World J Surg 4:183–193, 1980
Ishikawa M, Watanabe H, Yamagishi G, Masamune O, Gomi T, Takahashi T, Shoji K, Nagasaki A, Yamagata S: Crohn's disease, non-specific ulcers of the small intestine, and idiopathic proctocolitis in a Japanese university hospital from 1954 to 1974. Tohoku J Exp Med 118:97–109, 1976
Das SK, Montgomery RD: Chronic inflammatory bowel disease in Asian immigrants. Practitioner 221:747–749, 1978
Segal I, Tim LO, Hamilton DG, Walker ARP: The rarity of ulcerative colitis in South African blacks. Am J Gastroenterol 74:332–336, 1980
Wigley RD, MacLaurin BP: A study of ulcerative colitis in New Zealand, showing a low incidence in Maoris. Br Med J 2:228–231, 1962
Miller DS, Keighley AC, Langman MJS: Changing patterns in epidemiology of Crohn's disease. Lancet 2:691–693, 1974
Harries AD, Baird A, Rhodes J, Mayberry JF: Has the rising incidence of Crohn's disease reached a plateau? Br Med J 284:235, 1982
Sedlack RE, Nobrega FR, Kurland LT, Sauer WG: Inflammatory colon disease in Rochester, Minnesota, 1935–1964. Gastroenterology 62:935–941, 1972
Evans JG, Acheson ED: An epidemiological study of ulcerative colitis and regional enteritis in the Oxford area. Gut 6:311–324, 1965
Kyle J, Stark G: Fall in the incidence of Crohn's disease. Gut 21:340–343, 1980
Brahme F, Lindstrom C, Wenckert A: Crohn's disease in a defined population. Gastroenterology 69:342–351, 1975
Bonnevie O, Riis R, Anthonisen R: An epidemiological study of ulcerative colitis in Copenhagen County. Scand J Gastroenterol 3:432–438, 1968
Binder V, Both H, Hansen PK, Hendriksen C, Kreiner S, Torp-Pedersen K: Incidence and prevalence of ulcerative colitis and Crohn's disease in the county of Copenhagen, 1962 to 1978. Gastroenterology 83:563–568, 1982
Moller C, Linden F: Ulcerative colitis in Finland: I. Cases treated at central Hospitals, 1956–1967. Dis Colon Rectum 14:259–263, 1971
Ustvedt HJ: Ulcerative colitis: A study of all cases discharged from Norwegian hospitals in the ten-year period 1946–1955.In Recent Studies in Epidemiology. J Pemberton (ed). Thomas, Springfield, Illinois, 1958, pp 23–34
Gjone E, Myren J: Colitis ulcerosa i Norge. Nord Med 71:143–145, 1964
Myren J, Gjone E, Hertzberg JN, Rygvold O, Semb LS, Fretheim B: Epidemiology of ulcerative colitis and regional enterocolitis (Crohn's disease) in Norway. Scand J Gastroenterol 6:511–514, 1971
Gilat T, Ribak J, Benaroya Y, Zemishlany Z, Weissman I: Ulcerative colitis in the Jewish population of Tel-Aviv Jafo I. Epidemiology. Gastroenterology 66:335–342, 1974
Nedbal J, Maratka Z: Ulcerative proctocolitis in Czechoslovakia. Am J Proctol 19:106–114, 1968
Eason RJ, Lee SP, Tasman-Jones C: Inflammatory bowel disease in Auckland, New Zealand. Aust NZ J Med 12:125–131, 1982
Sedlack RE, Whisnant J, Elveback LR, Kurland LR: Incidence of Crohn's disease in Olmsted County, Minnesota, 1945–1975. Am J Epidemiol 112:759–763, 1980
Smith IS, Young S, Gillespie G, O'Connor J, Bell JR: Epidemiological aspects of Crohn's disease in Clydesdale 1961–1970. Gut 16:62–67, 1975
Keighley A, Miller DS, Hughes AO, Langman MJS: The demographic and social characteristics of patients with Crohn's disease in the Nottingham area. Scand J Gastroenterol 11:293–296, 1976
Mayberry J, Rhodes J, Hughes LE: Incidence of Crohn's disease in Cardiff between 1934 and 1977. Gut 20:602–608, 1979
Krause U: Epidemiology in Sweden.In Regional Enteritis (Crohn's Disease). A Engel, T Larson (eds). Skandia International Symposia, Nordiska Bokhandelns Forlan, Stockholm, 1971
Bergman L, Krause U: The incidence of Crohn's disease in central Sweden. Scand J Gastroenterol 10:725–729, 1975
Norlen BJ, Krause U, Bergman L: An epidemiological study of Crohn's disease. Scand J Gastroenterol 5:385–390, 1970
Hoj L, Jensen PB, Bonnevie O, Riis P: An epidemiological study of regional enteritis and acute ileitis in Copenhagen County. Scand J Gastroenterol 8:381–384, 1973
Havia T, Thomasson B: Crohn's disease. Acta Chir Scand 138:844–847, 1972
Gjone E, Orning OM, Myren J: Crohn's disease in Norway 1956–1963. Gut 7:372–374, 1966
Rozen P, Zonis J, Yukutiel P, Gilat T: Crohn's disease in the Jewish population of Tel-Aviv-Yafo. Gastroenterology 76:25–30, 1979
Fahrlander H, Baerlocher CH: Clinical features and epidemiological data on Crohn's disease in the Basle area. Scand J Gastroenterol 6:657–662, 1971
Brom B, Bank S, Marks IN, Barbezat GO, Raynham B: Crohn's disease in the Cape: A follow-up study of 24 cases and a review of the diagnosis and management. S Afr Med J 42:1099–1107, 1968
Novis BH, Marks IN, Bank S, Louw JH: Incidence of Crohn's disease at Groote Schuur Hospital during 1970–1974. S Afr Med J 49:693–697, 1975
Hellers G: Crohn's disease in Stockholm County 1955–1974. Acta Chir Scand (Suppl 490):16–30, 1979
Gilat T, Rozen P: Epidemiology of Crohn's disease and ulcerative colitis: Etiologic implications. Isr J Med Sci 15:305–308, 1979
Kyle J: An epidemiological study of Crohn's disease in northeast Scotland. Gastroenterology 61:826–833, 1971
Author information
Authors and Affiliations
Additional information
Supported in part by grants AM 18021 and AM 20467 from the National Institute of Arthritis, Metabolism and Digestive Diseases. Dr. Lilienfeld is a recipient of Research Career Award K06-GM 13091 from the National Institute of General Medical Sciences.
Rights and permissions
About this article
Cite this article
Calkins, B.M., Lilienfeld, A.M., Garland, C.F. et al. Trends in incidence rates of ulcerative colitis and Crohn's disease. Digest Dis Sci 29, 913–920 (1984). https://doi.org/10.1007/BF01312480
Received:
Revised:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01312480