Summary
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1.
Fourteen of 30 vaccinated cattle became carriers of foot-and-mouth disease following exposure to virus Types A, O, and C. Nineteen of 32 unvaccinated cattle similarly exposed became carriers. A purified virus acetylethyleneimine-inactivated, oil adjuvant vaccine was used.
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2.
No appreciable differences were observed among the 3 virus strains in the number of carriers produced or the virus titers of oesophageal-pharyngeal fluid. The number of carriers was lower than might be expected on the basis of previous studies using a strain isolated from carrier cattle.
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3.
Previous work was confirmed by the finding that the immune status of the cattle exposed to the three strains did not prevent the establishment of the carrier state. Neither was there a demonstrable relationship between the presence of epithelial lesions and the development of the carrier state.
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4.
Mean virus titers of oesophageal-pharyngeal fluid from vaccinated and unvaccinated carriers were of the same order.
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McVicar, J.W., Sutmoller, P. The epizootiological importance of foot-and-mouth disease carriers. Archiv f Virusforschung 26, 217–224 (1969). https://doi.org/10.1007/BF01242374
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DOI: https://doi.org/10.1007/BF01242374