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A novel method for reducing the RNA content of single cell protein isolates

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Summary

An ion-exchange method is described for the removal of RNA from soluble homogenates of microorganisms. The protein obtained by this gentle method is functionally unchanged and has a maximum RNA to protein ratio (w/w) of 0.03. Recoveries of protein are in excess of 60%. The resin can be regenerated and the process is rapid. This process is the subject of United States patent 4,330,464 (1982) assigned to George Weston Ltd. (Canada).

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Authors and Affiliations

  1. Department of Biochemistry, University of Toronto, Canada

    P. N. Lewis & H. G. Lawford

  2. Weston Research Centre, Toronto, Ontario

    A. Kligerman & G. R. Lawford

Authors
  1. P. N. Lewis
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  2. H. G. Lawford
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  3. A. Kligerman
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  4. G. R. Lawford
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Lewis, P.N., Lawford, H.G., Kligerman, A. et al. A novel method for reducing the RNA content of single cell protein isolates. Biotechnol Lett 4, 441–446 (1982). https://doi.org/10.1007/BF01134593

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  • DOI: https://doi.org/10.1007/BF01134593

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