Skip to main content
Log in

Prebiotic polypeptides and the origin of biological information

  • Published:
Naturwissenschaften Aims and scope Submit manuscript

Abstract

Recent data on the origin of biological information are reviewed. These data corroborate the view that polyamino acids were the first informational polymers. The source of information is seen in the chemical reactivity of amino acids, their prebiotic abundance and the prebiotic environment. Evidence is presented in favor of Matsuno's protohypercycle that may have preceded Eigen's hypercycle, but that involves a translation of information from polypeptides into that of polynucleotides.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Dunnill, P.: Nature210, 1267 (1966)

    Google Scholar 

  2. Woese, C.R.: The Genetic Code. Hagerstown: Harper & Row 1967

    Google Scholar 

  3. Pelc, S.R., Welton, M.G.E.: Nature209, 868 (1970)

    Google Scholar 

  4. Thomas, B.R.: Biochem. Biophys. Res. Commun.40, 1281 (1970)

    Google Scholar 

  5. Lacey, Jr., J.C., Weber, A.L., in: Protein Structure and Evolution, p. 213 (eds. L. Fox et al.). New York: Dekker 1976

    Google Scholar 

  6. Eigen, M.: Naturwissenschaften58, 465 (1971)

    Google Scholar 

  7. Fox, S.W., Dose, K.: Molecular Evolution and the Origin of Life. New York: Dekker 1977

    Google Scholar 

  8. Fox, S.W., Harada, K., Kendrick, J.: Science129, 1221 (1959)

    Google Scholar 

  9. Fox, S.W., Harada, K., Vegotsky, A.: Experientia15, 81 (1959)

    Google Scholar 

  10. Fox, S.W.: Naturwissenschaften67, 576 (1980)

    Google Scholar 

  11. Fox, S.W.: Am. Biol. Teacher43, 127 (1981)

    Google Scholar 

  12. Dose, K., Rauchfuß, H.: Chemische Evolution und der Ursprung lebender Systeme. Stuttgart: Wissenschaftl. Verlagsges. 1975

    Google Scholar 

  13. Melius, P.: BioSystems11, 125 (1979)

    Google Scholar 

  14. Nakashima, T., et al.: Int. J. Quant. Chem. QBS4, 65 (1977)

    Google Scholar 

  15. Hartmann, J., Brand, M.C., Dose, K.: BioSystems13, 141 (1981)

    Google Scholar 

  16. Heinz, B., Ried, W., Dose, K.: Angew. Chem. Int. Ed.18, 478, 483 (1979)

    Google Scholar 

  17. Heinz, B., Ried, W.: BioSystems14, 33 (1981)

    Google Scholar 

  18. Paecht-Horowitz, M.: ibid.9, 93 (1977)

    Google Scholar 

  19. Nakashima, T., Fox, S.W.: ibid.14, 151 (1981)

    Google Scholar 

  20. Mutter, M.: Liebigs Ann. Chem.1975, 901

  21. Kenyon, D.H., Steinman, G.: Biochemical Predestination. New York: McGraw-Hill 1969

    Google Scholar 

  22. Steinman, G.: Arch. Biochem. Biophys.119, 76 (1967)

    Google Scholar 

  23. Steinman, G.: ibid.121, 533 (1967)

    Google Scholar 

  24. Steinman, G., Cole, M.U.: Proc. Nat. Acad. Sci. USA56, 735 (1967)

    Google Scholar 

  25. Mutter, M.: Int. J. Peptide Protein Res.13, 274 (1979)

    Google Scholar 

  26. Dose, K., Hartmann, J., Brand, C.M.: BioSystems15, 195 (1982)

    Google Scholar 

  27. Sober, H.D. (ed.): Handbook of Biochemistry, Table C-122. Cleveland: The Chemical Rubber Co. 1970

    Google Scholar 

  28. Dose, K., et al.: in preparation

  29. Sumper, M., Luce, R.: Proc. Nat. Acad. Sci. USA72, 162 (1975)

    Google Scholar 

  30. Matsuno, K.: BioSystems15, 1 (1982)

    Google Scholar 

  31. Nakashima, T., Fox, S.W.: J. Mol. Evol.15, 161 (1980)

    Google Scholar 

  32. Fox, S.W., Nakashima, T.: BioSystems12, 155 (1980)

    Google Scholar 

  33. Fox, S.W., in: Science and Scientists, p. 39 (eds. M. Kageyama et al.). Tokyo: Japan Sci. Soc. 1981

    Google Scholar 

  34. Fox, S.W.: Mol. Cell. Biochem.3, 129 (1974)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Dose, K. Prebiotic polypeptides and the origin of biological information. Naturwissenschaften 70, 378–382 (1983). https://doi.org/10.1007/BF01047173

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01047173

Keywords

Navigation