Summary
A phenol tolerant thermophile,Bacillus stearothermophilus BR219, catabolizes phenol via a plasmid encoded catecholmeta pathway. Direct and selective inhibition of catechol 2,3-dioxygenase encoded in this pathway by tetracycline results in accumulation of the specialty chemical catechol. Optimal conditions for catechol production are presented.
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Gurujeyalakshmi, G., Oriel, P. A thermophilic process for catechol production from phenol. Biotechnol Lett 11, 689–694 (1989). https://doi.org/10.1007/BF01044098
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DOI: https://doi.org/10.1007/BF01044098