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Effect of aeration rate and influence of pCO2 in large-scale cultures ofCatharanthus roseus cells

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Summary

Catharanthus roseus cells were grown at various aeration rates using normal or CO2-enriched air. Kinetic data showed a detrimental effect of the increase of the gassing rate on the growth characteristics due to CO2 stripping. When the CO2 partial pressure in the culture was maintained at a constant level of 20 mbar, better growth and enhanced conversion yields were obtained.

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Authors and Affiliations

  1. Département de Génie Biochimique et Alimentaire, UA-CNRS-No 544, Institut National des Sciences Appliquées, Avenue de Rangueil, F-31077, Toulouse Cédex, France

    Jean Paul Ducos & Alain Pareilleux

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  1. Jean Paul Ducos
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  2. Alain Pareilleux
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Ducos, J.P., Pareilleux, A. Effect of aeration rate and influence of pCO2 in large-scale cultures ofCatharanthus roseus cells. Appl Microbiol Biotechnol 25, 101–105 (1986). https://doi.org/10.1007/BF00938932

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  • DOI: https://doi.org/10.1007/BF00938932

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