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Relationship between precorneal retention of viscous eye drops and tear fluid composition

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Abstract

The influence of viscolysers on the precorneal residence of a fluorescent tracer was determined, using slit lamp fluorophotometry. The solution acceptability was evaluated by the volunteers by answering a standard questionnaire.

The relationship between precorneal retention of viscous eye drops, discomfort and tear fluid composition after instillation of various cellulosic solutions was examined. Irritating hydroxypropylcellulose solution increases the total protein concentration of tears, without change in the ratio of lysozyme to total protein.

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Abbreviations

HEC:

hydroxyethylcellulose

HPC:

hydroxypropylcellulose

HPMC:

hydroxypropyl-methylcellulose

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Authors and Affiliations

  1. University of Antwerp (UIA), Belgium

    A. Ludwig & M. Van Ooteghem

  2. The Netherlands Ophthalmic Research Institute, Amsterdam, The Netherlands

    N. J. van Haeringen & V. M. W. Bodelier

Authors
  1. A. Ludwig
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  2. N. J. van Haeringen
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  3. V. M. W. Bodelier
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  4. M. Van Ooteghem
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Ludwig, A., van Haeringen, N.J., Bodelier, V.M.W. et al. Relationship between precorneal retention of viscous eye drops and tear fluid composition. Int Ophthalmol 16, 23–26 (1992). https://doi.org/10.1007/BF00917068

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  • DOI: https://doi.org/10.1007/BF00917068

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